A nuclear localization signal or sequence (NLS) is an amino acid sequence that 'tags' a protein for import into the cell nucleus by nuclear transport...
15 KB (2,036 words) - 22:39, 23 May 2025
Lamin (redirect from Nuclear lamins)
the type of lamin. However, all C-terminal domains contain a nuclear localization sequence (NLS). Similar to other IF proteins, lamins self-assemble into...
18 KB (2,198 words) - 02:12, 10 March 2025
Signal peptide (redirect from Target sequence)
referred to as signal sequence, targeting signal, localization signal, localization sequence, transit peptide, leader sequence or leader peptide) is a...
15 KB (1,777 words) - 07:49, 20 May 2025
the cytoplasm and nucleus, via a conserved nuclear export sequence (NES) and a nuclear localization sequence (NLS), both necessary for proper functioning...
12 KB (1,387 words) - 06:32, 20 May 2025
Protein targeting (redirect from Protein localization)
through the addition of a nuclear localization sequence (NLS) that promotes passage through the nuclear envelope via nuclear pores. While some proteins...
53 KB (6,405 words) - 19:55, 19 June 2025
Importin (section Nuclear protein import cycle)
nucleus. It does so by binding to specific recognition sequences, called nuclear localization sequences (NLS). Importin has two subunits, importin α and importin...
18 KB (2,026 words) - 20:24, 2 April 2024
"Identification of hSRP1 alpha as a functional receptor for nuclear localization sequences". Science. 268 (5213): 1049–53. Bibcode:1995Sci...268.1049W...
13 KB (1,632 words) - 12:07, 22 December 2023
protein to study nuclear localization signals (NLSs). It is imported into the nucleus by its interaction with importin α. The NLS sequence is PKKKRKV. SV40...
12 KB (1,413 words) - 05:37, 24 June 2025
releasing the catalytic subunit. The catalytic subunit has a nuclear localization sequence which prompts it to go into the nucleus and phosphorylate other...
42 KB (5,255 words) - 08:55, 25 May 2025
mRNA in the cytoplasm. However, hnRNPs also have their own nuclear localization sequences (NLS) and are therefore found mainly in the nucleus. Though...
16 KB (1,987 words) - 08:35, 13 March 2025
state, NFAT cannot enter the nucleus as its nuclear localization sequence (NLS) cannot be recognized by nuclear transporters due to phosphorylation by GSK-3...
44 KB (5,378 words) - 07:54, 5 May 2025
Look up localization, L10n, or localize in Wiktionary, the free dictionary. Localization or localisation may refer to: Localization of function, locating...
4 KB (506 words) - 17:52, 1 May 2025
icosahedral assembly. The C-terminus also contains a basic nuclear localization sequence,: 316 while the N-terminus - which is oriented toward the center...
11 KB (1,059 words) - 00:01, 3 December 2023
dominant role in recognition of the DR sequences in the transposon. The RED subdomain overlaps with the nuclear localization signal, but its function remains...
30 KB (2,765 words) - 14:58, 16 May 2025
This protein is a karyopherin which interacts with nuclear localization sequence to target nuclear proteins to the nucleus. The classical karyopherin...
12 KB (1,531 words) - 13:22, 23 December 2023
adds a C-terminal PY type nuclear localization sequence, which presumably explains why NeuN/Fox-3 protein can be both nuclear and, in some cell types,...
8 KB (982 words) - 08:12, 6 June 2025
known life forms List of Archaea genera List of sequenced archaeal genomes Nuclear localization sequence Stirrup protein domain The Surprising Archaea (book)...
157 KB (16,967 words) - 15:01, 27 June 2025
FGF1 can also function intracellularly. The protein has a nuclear localization sequence (NLS) but the route that FGF1 takes to get to the nucleus is...
20 KB (2,311 words) - 22:01, 16 July 2024
of which nuclear localization signal (NLS) are best characterized. Several NLS sequences are known, generally containing a conserved sequence with basic...
28 KB (3,288 words) - 21:05, 23 June 2025
stable throughout the cell cycle and is localized to the nucleus due to the presence of a nuclear localization sequence (NLS). SCF-Fbw7 targets Sic1—when at...
16 KB (2,021 words) - 15:42, 12 April 2025
karyopherin proteins. Importin α is known to bind to the nuclear localization signal (NLS) sequence of nucleus targeted proteins. After this recognition,...
14 KB (1,829 words) - 04:27, 27 May 2025
Cyclin E/Cdk2 (section Localization)
typically appears as a nuclear protein in images as its nuclear import is more rapid than its export. Cyclin E's nuclear localization sequence (NLS) allows the...
11 KB (1,404 words) - 07:30, 19 November 2024
accomplished via removal of nuclear localization sequence (NLS)-obscuring phosphates and phosphorylation of the nuclear export signal. It is thought...
22 KB (2,818 words) - 07:39, 3 June 2024
nucleus from the cytoplasm carry nuclear localization signals (NLS) that are bound by importins. An NLS is a sequence of amino acids that acts as a tag...
8 KB (976 words) - 22:34, 1 July 2024
interacts with carboxyl-terminal of Hsp90 and binds to the AhR nuclear localization sequence (NLS) preventing the inappropriate trafficking of the receptor...
52 KB (5,999 words) - 06:16, 5 February 2025
predicted nuclear localization sequence, while the blue domain is the remainder of the LOC105377021 exon. According to Ali2D (a multiple sequence alignment...
15 KB (1,220 words) - 08:12, 28 May 2025
N-terminal propiece cleavage product (ppIL-1α), which contains a nuclear localization sequence (NLS), and translocates to the nucleus, functioning as a transcription...
50 KB (6,093 words) - 20:45, 19 November 2024
Nucleoplasm (redirect from Nuclear sap)
a third of these have been found to localize to the nucleoplasm via targeting by a nuclear localization sequence (NLS). Cytosolic proteins, known as importins...
17 KB (1,949 words) - 19:41, 24 May 2025
enhances the nuclear translocation of DNA cytosine-5-methyltransferase 1 (DNMT1) via phosphorylation of the nuclear localization sequence by the AKT kinase"...
63 KB (7,479 words) - 18:19, 9 June 2025
Süel KE, Louis TH, Zhang Z, Chook YM (August 2006). "Rules for nuclear localization sequence recognition by karyopherin beta 2". Cell. 126 (3): 543–58. doi:10...
4 KB (527 words) - 01:51, 17 April 2022