The quasispecies model is a description of the process of the Darwinian evolution of certain self-replicating entities within the framework of physical...

replicating and quasispecies, respectively); (2) they performed only a single, random simulation to test the selectability. The quasispecies model describes...

A viral quasispecies is a population structure of viruses with a large number of variant genomes (related by mutations). Quasispecies result from high...

less successful strategies decline. Unlike other models of replication—such as the quasispecies model—the replicator equation allows the fitness of each...

One of the main theoretical models applied to viral evolution is the quasispecies model, which defines a viral quasispecies as a group of closely related...

work with the German Nobel Laureate Manfred Eigen in developing the quasispecies model. His work has made great strides in the understanding of viruses and...

information increases over the course of time in a simple model of evolution known as the quasispecies model. This is demonstrably not true for the standard measure...

'w’ that incorporates natural selection and mutation, according to quasispecies model, is given by: w = [ a ⋅ Q 3 a ⋅ μ 0 0 μ Q 2 μ 0 0 2 μ Q μ 0 0 3 μ...

mutations that cause antiviral resistance. This effect, called the quasispecies model, results in immense variation in any given sample of virus, and gives...

Price – Price equation – punctuated equilibrium quantum evolution – quasispecies model race (biology) – Red Queen hypothesis – recapitulation theory – recent...

quasispecies at a low but evolutionarily neutral and highly connected (that is, flat) region in the fitness landscape will outcompete a quasispecies located...

pulses of energy. In addition, Eigen's name is linked with the theory of quasispecies, the error threshold, error catastrophe, Eigen's paradox, and the chemical...

host animal. These quasispecies do not necessarily give rise to population-wide new organisms. The rate of proliferation of quasispecies has significant...

coined by Manfred Eigen in his mathematical evolutionary theory of the quasispecies. The term is most widely used to refer to mutation accumulation to the...

hypercycle concept, propose a hypercycle theory and introduce the concept of quasispecies 1982 (1982): Discovery of ribozyme catalytic properties 2001 (2001):...

research to studying various problems in evolutionary dynamics using quasispecies models. His seminal work centered on the key question of the evolutionary...

investigation of within-host evolution, as the full diversity of an infecting quasispecies may be uncovered given enough sequencing effort. Bacterial phylodynamics...

often exist as quasispecies or swarms of viruses of the same species but with slightly different genome nucleoside sequences. Such quasispecies are a prime...

hypercycle of Manfred Eigen and Peter Schuster, which includes the concept of quasispecies, the (M,R) systems of Robert Rosen, autopoiesis (or self-building) of...

{\displaystyle 10^{-5}} per generation. Negative selection Dysgenics Viral quasispecies Crow, James F.; Kimura, Motoo (1970). An Introduction to Population Genetics...

in 1989. During his studies, he collaborated with Peter Schuster on quasispecies theory, and with Karl Sigmund on evolution of cooperation. Nowak received...

individuals are quite irrelevant. This becomes clearer when referring to Viral quasispecies, in survival of the flattest, which makes it clear to survive makes no...

response, host gene expression profiling, and viral factors such as quasispecies. Harris is also collaborating with investigators at the UC Berkeley College...

Mutational robustness is thought to be one driver for theoretical viral quasispecies formation. Natural selection can select directly or indirectly for robustness...

A, Chumakov K, Brau A (2001). "Quantitative mutant analysis of viral quasispecies by chip-based matrix-assisted laser desorption/ ionization time-of-flight...

PMID 18852697. Domingo E, Sheldon J, Perales C (June 2012). "Viral quasispecies evolution". Microbiology and Molecular Biology Reviews. 76 (2): 159–216...

T helper cells that it infects, and regulatory T cells. These three quasispecies apply selective pressure on one another and co-evolve in such a way that...

Beards G, Elias E, Pillay D (1999). "Analysis of hepatitis B virus quasispecies changes during emergence and reversion of lamivudine resistance in liver...

mutation rate produces so many variants of the virus it is considered a quasispecies rather than a conventional virus species. Entry into host cells occur...

non-equilibrium statistical mechanics to solve Eigen’s equations of molecular quasispecies for realistic fitness landscapes . He developed an ensemble approach...