• Thumbnail for RNA splicing
    methods of RNA splicing occur in nature; the type of splicing depends on the structure of the spliced intron and the catalysts required for splicing to occur...
    38 KB (4,660 words) - 16:36, 26 February 2025
  • Thumbnail for Alternative splicing
    Alternative splicing, alternative RNA splicing, or differential splicing, is an alternative splicing process during gene expression that allows a single...
    62 KB (7,812 words) - 02:47, 17 February 2025
  • Small nuclear RNA (snRNA) is a class of small RNA molecules that are found within the splicing speckles and Cajal bodies of the cell nucleus in eukaryotic...
    18 KB (2,335 words) - 16:05, 28 November 2024
  • Intron (category RNA splicing)
    Exon mRNA Eukaryotic chromosome fine structure Small t intron Splicing: Alternative splicing Exitron Minor spliceosome Outron Function MicroRNA Others:...
    47 KB (5,853 words) - 21:36, 25 April 2025
  • Thumbnail for Messenger RNA
    process of RNA splicing, leaving only exons, regions that will encode the protein. This exon sequence constitutes mature mRNA. Mature mRNA is then read...
    51 KB (6,206 words) - 13:31, 24 May 2025
  • Thumbnail for Mature messenger RNA
    process, RNA splicing removes the non-coding RNA introns leaving behind the exons, which are then spliced and joined together to form the mature mRNA. Splicing...
    6 KB (596 words) - 01:14, 26 May 2025
  • Thumbnail for Post-transcriptional modification
    chemical structure of the RNA molecule: the addition of a 5' cap, the addition of a 3' polyadenylated tail, and RNA splicing. Such processing is vital...
    11 KB (1,432 words) - 23:35, 24 July 2024
  • hESCs by ensuring genes undergo RNA splicing to create a mature RNA transcript. The SON gene is required for RNA splicing of transcripts encoding the cell-cycle...
    25 KB (2,954 words) - 11:16, 11 May 2024
  • Thumbnail for Exon
    Exon (category RNA splicing)
    will form a part of the final mature RNA produced by that gene after introns have been removed by RNA splicing. The term exon refers to both the DNA...
    13 KB (1,522 words) - 13:01, 21 April 2025
  • Thumbnail for Primary transcript
    3'-polyadenylation, and alternative splicing. In particular, alternative splicing directly contributes to the diversity of mRNA found in cells. The modifications...
    22 KB (2,668 words) - 08:52, 16 December 2024
  • Thumbnail for Circular RNA
    the protein product. The spliceosome, a protein-RNA complex located in the nucleus, catalyzes splicing in the following manner: The spliceosome recognizes...
    56 KB (6,708 words) - 20:49, 30 April 2025
  • Thumbnail for Ribozyme
    Ribozyme (redirect from Catalytic RNA)
    (ribonucleic acid enzymes) are RNA molecules that have the ability to catalyze specific biochemical reactions, including RNA splicing in gene expression, similar...
    44 KB (5,382 words) - 17:57, 28 April 2025
  • Thumbnail for Protein splicing
    (ATP) or guanosine triphosphate (GTP). Normally, splicing is associated only with pre-mRNA splicing. This precursor protein contains three segments—an...
    31 KB (3,821 words) - 00:40, 26 May 2025
  • to be removed after transcription through a process termed RNA splicing. Splicing of RNA transcripts requires a highly precise and coordinated sequence...
    42 KB (4,639 words) - 22:36, 1 April 2025
  • Thumbnail for Cell nucleus
    organization of the gene-expression machinery splicing snRNPs and other splicing proteins necessary for pre-mRNA processing. Because of a cell's changing requirements...
    88 KB (10,011 words) - 10:50, 11 May 2025
  • Thumbnail for Protein isoform
    generally not considered. (For that, see Proteoforms.) Through RNA splicing mechanisms, mRNA has the ability to select different protein-coding segments...
    17 KB (2,010 words) - 02:30, 6 November 2024
  • Thumbnail for Serine/arginine-rich splicing factor 1
    Serine/arginine-rich splicing factor 1 (SRSF1) also known as alternative splicing factor 1 (ASF1), pre-mRNA-splicing factor SF2 (SF2) or ASF1/SF2 is a...
    21 KB (2,574 words) - 16:59, 7 August 2024
  • Thumbnail for Zebrafish
    initiate RNA splicing. These genes have the DNA base pairs AC and TG as repeated sequences at the ends of each intron. On the 3'ss (3' splicing site), the...
    113 KB (12,480 words) - 19:19, 23 May 2025
  • Thumbnail for SR protein
    SR protein (section Splicing)
    alternative pre-mRNA splicing, mRNA export, genome stabilization, nonsense-mediated decay, and translation. SR proteins alternatively splice pre-mRNA by preferentially...
    27 KB (3,443 words) - 03:57, 30 October 2024
  • tRNAs. Whereas "normal" (cis-)splicing processes a single molecule, trans-splicing generates a single RNA transcript from multiple separate pre-mRNAs....
    12 KB (1,369 words) - 13:56, 25 May 2025
  • Thumbnail for RNA hydrolysis
    defective RNA. Splicing ribozymes catalyze RNA splicing, removing a section of RNA that contains a mutation and replacing it with well-functioning RNA. Existing...
    6 KB (740 words) - 02:24, 6 August 2024
  • Thumbnail for RNA
    transfer RNA (tRNA), microRNA (miRNA), small interfering RNA (siRNA), small nucleolar RNA (snoRNAs), Piwi-interacting RNA (piRNA), tRNA-derived small RNA (tsRNA)...
    65 KB (7,626 words) - 20:44, 25 May 2025
  • an exonic splicing enhancer (ESE) is a DNA sequence motif consisting of 6 bases within an exon that directs, or enhances, accurate splicing of heterogeneous...
    5 KB (596 words) - 19:24, 13 August 2023
  • of Cis-acting RNA elements that influence exons inclusion or exclusion during splicing. These sites are referred to as exonic splicing enhancers (ESEs)...
    39 KB (4,540 words) - 10:50, 22 May 2025
  • Thumbnail for Spliceosome
    Spliceosome (category RNA splicing)
    either sites of mRNA splicing or storage sites of mRNA splicing factors. It is now understood that nuclear speckles help concentrate splicing factors near...
    22 KB (2,809 words) - 02:49, 20 November 2024
  • Thumbnail for RNA-Seq
    mRNA transcripts, RNA-Seq can look at different populations of RNA to include total RNA, small RNA, such as miRNA, tRNA, and ribosomal profiling. RNA-Seq...
    88 KB (9,465 words) - 02:10, 14 May 2025
  • Thumbnail for Non-coding RNA
    RNAs such as microRNAs, siRNAs, piRNAs, snoRNAs, snRNAs, exRNAs, scaRNAs and the long ncRNAs such as Xist and HOTAIR. The number of non-coding RNAs within...
    67 KB (7,183 words) - 05:31, 23 May 2025
  • Thumbnail for RNA-binding protein FUS
    Moreau-Gachelin F (March 2001). "Identification of an RNA binding specificity for the potential splicing factor TLS". J. Biol. Chem. 276 (9): 6807–16. doi:10...
    32 KB (3,968 words) - 16:01, 6 February 2025
  • Thumbnail for Minigene
    affected mature RNA and the genes it expresses. Using minigenes as a splice reporting vector to explore the effects of RNA splicing regulation naturally...
    21 KB (2,427 words) - 08:41, 10 March 2024
  • Thumbnail for U2 spliceosomal RNA
    U2 snRNA has been theorized to serve a catalytic role in the chemistry of pre-RNA splicing as well. Similar to ribosomal RNAs (rRNAs), Sm snRNAs must...
    15 KB (1,784 words) - 02:26, 23 September 2021