methods of RNA splicing occur in nature; the type of splicing depends on the structure of the spliced intron and the catalysts required for splicing to occur...

Alternative splicing, alternative RNA splicing, or differential splicing, is an alternative splicing process during gene expression that allows a single...

Small nuclear RNA (snRNA) is a class of small RNA molecules that are found within the splicing speckles and Cajal bodies of the cell nucleus in eukaryotic...

Exon mRNA Eukaryotic chromosome fine structure Small t intron Splicing: Alternative splicing Exitron Minor spliceosome Outron Function MicroRNA Others:...

3'-polyadenylation, and alternative splicing. In particular, alternative splicing directly contributes to the diversity of mRNA found in cells. The modifications...

chemical structure of the RNA molecule: the addition of a 5' cap, the addition of a 3' polyadenylated tail, and RNA splicing. Such processing is vital...

hESCs by ensuring genes undergo RNA splicing to create a mature RNA transcript. The SON gene is required for RNA splicing of transcripts encoding the cell-cycle...

process, RNA splicing removes the non-coding RNA introns leaving behind the exons, which are then spliced and joined together to form the mature mRNA. Splicing...

will form a part of the final mature RNA produced by that gene after introns have been removed by RNA splicing. The term exon refers to both the DNA...

process of RNA splicing, leaving only exons, regions that will encode the protein. This exon sequence constitutes mature mRNA. Mature mRNA is then read...

generally not considered. (For that, see Proteoforms.) Through RNA splicing mechanisms, mRNA has the ability to select different protein-coding segments...

(ribonucleic acid enzymes) are RNA molecules that have the ability to catalyze specific biochemical reactions, including RNA splicing in gene expression, similar...

either sites of mRNA splicing or storage sites of mRNA splicing factors. It is now understood that nuclear speckles help concentrate splicing factors near...

of Cis-acting RNA elements that influence exons inclusion or exclusion during splicing. These sites are referred to as exonic splicing enhancers (ESEs)...

(ATP) or guanosine triphosphate (GTP). Normally, splicing is associated only with pre-mRNA splicing. This precursor protein contains three segments—an...

the protein product. The spliceosome, a protein-RNA complex located in the nucleus, catalyzes splicing in the following manner: The spliceosome recognizes...

to be removed after transcription through a process termed RNA splicing. Splicing of RNA transcripts requires a highly precise and coordinated sequence...

Serine/arginine-rich splicing factor 1 (SRSF1) also known as alternative splicing factor 1 (ASF1), pre-mRNA-splicing factor SF2 (SF2) or ASF1/SF2 is a...

an exonic splicing enhancer (ESE) is a DNA sequence motif consisting of 6 bases within an exon that directs, or enhances, accurate splicing of heterogeneous...

organization of the gene-expression machinery splicing snRNPs and other splicing proteins necessary for pre-mRNA processing. Because of a cell's changing requirements...

alternative pre-mRNA splicing, mRNA export, genome stabilization, nonsense-mediated decay, and translation. SR proteins alternatively splice pre-mRNA by preferentially...

U2 snRNA has been theorized to serve a catalytic role in the chemistry of pre-RNA splicing as well. Similar to ribosomal RNAs (rRNAs), Sm snRNAs must...

mRNA transcripts, RNA-Seq can look at different populations of RNA to include total RNA, small RNA, such as miRNA, tRNA, and ribosomal profiling. RNA-Seq...

Moreau-Gachelin F (March 2001). "Identification of an RNA binding specificity for the potential splicing factor TLS". J. Biol. Chem. 276 (9): 6807–16. doi:10...

pre-mRNA, and various other proteins to assemble a spliceosome, a large RNA-protein molecular complex upon which splicing of pre-mRNA occurs. Splicing, or...

molecule. RNA editing is relatively rare, with common forms of RNA processing (e.g. splicing, 5'-capping, and 3'-polyadenylation) not usually considered...

fellowship, she was instrumental in the research that led to the discovery of RNA splicing and split genes, which awarded Sharp the 1993 Nobel Prize in Physiology...

initiate RNA splicing. These genes have the DNA base pairs AC and TG as repeated sequences at the ends of each intron. On the 3'ss (3' splicing site), the...

important in splicing activity, where its role is to bring the catalytic site to the splice site. Base-pair specificity of the U6 snRNA allows the U6...

tRNAs. Whereas "normal" (cis-)splicing processes a single molecule, trans-splicing generates a single RNA transcript from multiple separate pre-mRNAs....