• Thumbnail for Fas receptor
    The Fas receptor, also known as Fas, FasR, apoptosis antigen 1 (APO-1 or APT), cluster of differentiation 95 (CD95) or tumor necrosis factor receptor superfamily...
    23 KB (2,685 words) - 14:02, 24 May 2025
  • Thumbnail for Fas ligand
    superfamily. It binds to the Fas receptor (CD95) to induce apoptosis, and also activates non-apoptotic pathways such as NF-κB and MAPK. FasL exists in membrane-bound...
    33 KB (3,892 words) - 15:08, 31 July 2025
  • Thumbnail for Activation-induced cell death
    programmed cell death caused by the interaction of Fas receptors (Fas, CD95) and Fas ligands (FasL, CD95 ligand). AICD is a negative regulator of activated...
    4 KB (475 words) - 17:58, 21 April 2025
  • Look up FAS, Fas, or fas in Wiktionary, the free dictionary. Fas or FAS may refer to: Fez, Morocco, alternate spelling Poti, Georgia, a port city in Georgia...
    2 KB (276 words) - 08:19, 4 January 2025
  • Thumbnail for FADD
    protein that bridges members of the tumor necrosis factor receptor superfamily, such as the Fas-receptor, to procaspases 8 and 10 to form the death-inducing...
    34 KB (4,194 words) - 06:53, 2 June 2025
  • Thumbnail for Lymphoproliferative disorders
    antigen leads to coexpression of Fas and Fas receptor on the T cell surface. The engagement of Fas by Fas receptor results in apoptosis of the cell and...
    8 KB (772 words) - 04:25, 15 July 2025
  • Thumbnail for Erythropoietin receptor
    Additionally, EpoR has been implicated in suppressing expression of death receptors Fas, Trail and TNFa that negatively affect erythropoiesis. Based on current...
    29 KB (3,348 words) - 16:30, 17 July 2025
  • Thumbnail for Apoptosis
    uncontrolled cell proliferation, such as cancer. Some factors like Fas receptors and caspases promote apoptosis, while some members of the Bcl-2 family...
    94 KB (10,849 words) - 20:48, 23 July 2025
  • Thumbnail for Cell death
    interaction of Fas receptor (Fas, CD95)and Fas ligand (FasL, CD95 ligand). It occurs as a result of repeated stimulation of specific T-cell receptors (TCR) and...
    21 KB (2,738 words) - 17:32, 16 June 2025
  • Thumbnail for Thrombospondin
    to CD36, leading to the expression of FAS ligand (FasL), which activates its specific, ubiquitous receptor, Fas. This leads to the activation of caspases...
    6 KB (643 words) - 10:29, 22 May 2025
  • Thumbnail for TNF receptor superfamily
    refers to those members of the TNF receptor superfamily that contain a death domain, such as TNFR1, Fas receptor, DR4 and DR5. They were named after...
    9 KB (610 words) - 13:48, 14 January 2025
  • Thumbnail for Transforming growth factor beta
    protein 6 (DAXX) with the death receptor Fas, there is evidence of association and binding between DAXX and type 2 TGF-β receptor kinase, wherein DAXX binds...
    67 KB (8,184 words) - 21:14, 18 July 2025
  • Thumbnail for Fetal alcohol spectrum disorder
    severe to least severe) are: fetal alcohol syndrome (FAS), partial fetal alcohol syndrome (pFAS), alcohol-related neurodevelopmental disorder (ARND),...
    138 KB (15,863 words) - 02:19, 1 August 2025
  • Thumbnail for PDCD6
    to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient...
    10 KB (1,245 words) - 06:52, 19 July 2025
  • Thumbnail for Follicular atresia
    with five ligand-receptor systems involved in cell death: tumor necrosis factor alpha (TNF alpha) and receptors Fas ligand and receptors TNF-related apoptosis-inducing...
    28 KB (3,363 words) - 05:50, 19 July 2025
  • of. The other pathway is the Fas ligand pathway. In this pathway, a Fas ligand (FasL) on the CTL binds to Fas receptor (FasR) on the target cell. This pathway...
    3 KB (416 words) - 08:59, 30 June 2024
  • Thumbnail for Death-associated protein 6
    discovered through its cytoplasmic interaction with the classical death receptor Fas. It has been associated with heterochromatin and PML-NBs (Promyelocytic...
    11 KB (1,528 words) - 16:17, 17 July 2025
  • parasympathetic nervous system by selectively blocking the binding of ACh to its receptor in nerve cells. The nerve fibers of the parasympathetic system are responsible...
    28 KB (2,688 words) - 16:10, 17 July 2025
  • Thumbnail for Decoy receptor 3
    M68, is a soluble protein of the tumor necrosis factor receptor superfamily which inhibits Fas ligand-induced apoptosis. Dcr3 was identified in 1998 by...
    12 KB (1,243 words) - 05:35, 19 July 2025
  • Thumbnail for Envelope glycoprotein GP120
    proteins like caspases which may influence the upregulation of the death receptor Fas leading to apoptosis of neuronal cells, gp120 induces oxidative stress...
    21 KB (2,538 words) - 04:16, 10 July 2025
  • Thumbnail for Ligand (biochemistry)
    the function of the receptor that triggers a physiological response is called a receptor agonist. Ligands that bind to a receptor but fail to activate...
    29 KB (3,169 words) - 21:04, 9 June 2025
  • Thumbnail for Receptor (biochemistry)
    In biochemistry and pharmacology, receptors are chemical structures, composed of protein, that receive and transduce signals that may be integrated into...
    26 KB (2,673 words) - 05:54, 5 May 2025
  • Thumbnail for Natural killer cell
    cell receptors can also be differentiated based on function. Natural cytotoxicity receptors directly induce apoptosis (cell death) after binding to Fas ligand...
    75 KB (9,229 words) - 11:47, 4 July 2025
  • Thumbnail for Cytotoxic T cell
    the cell that expressed Fas. CD8 T cells can also show Activation Induced Cell Death or AICD which is mediated by CD3 receptor complex. Recently, a platelet...
    31 KB (3,853 words) - 19:57, 17 July 2025
  • Thumbnail for Death-inducing signaling complex
    complex formed by members of the death receptor family of apoptosis-inducing cellular receptors. A typical example is FasR, which forms the DISC upon trimerization...
    7 KB (942 words) - 13:54, 14 April 2025
  • proteins like caspases, which may influence the upregulation of the death receptor Fas leading to apoptosis. HIV enters the brain early on in the infection...
    32 KB (3,822 words) - 17:12, 26 May 2025
  • Interleukin-10 receptor subunit alpha precursor - Homo sapiens (Human)". www.uniprot.org. Retrieved 2015-10-13. "IL10RB - Interleukin-10 receptor subunit beta...
    96 KB (492 words) - 06:06, 25 November 2024
  • Thumbnail for Free fatty acid receptor 3
    for SC-FAs to activate cells as well as the ability of SC-FAs to activate FFAR2 or, in the case of butyric acid, hydroxycarboxylic acid receptor 2, the...
    51 KB (6,286 words) - 16:37, 17 July 2025
  • Thumbnail for 5-HT1A receptor
    The serotonin 1A receptor (or 5-HT1A receptor) is a subtype of serotonin receptors, or 5-HT receptors, that binds serotonin, also known as 5-HT, a neurotransmitter...
    59 KB (6,182 words) - 04:57, 19 July 2025
  • Thumbnail for Alternative splicing
    membrane-bound form of the Fas receptor, which promotes apoptosis, or programmed cell death. Increased expression of Fas receptor in skin cells chronically...
    62 KB (7,818 words) - 20:08, 23 July 2025