• Thumbnail for Small interfering RNA
    Small interfering RNA (siRNA), sometimes known as short interfering RNA or silencing RNA, is a class of double-stranded non-coding RNA molecules, typically...
    60 KB (7,300 words) - 14:35, 22 July 2025
  • Thumbnail for Small RNA
    including piwi-interacting RNA (piRNA) and its subspecies repeat associated small interfering RNA (rasiRNA). Small RNA "is unable to induce RNAi alone...
    18 KB (1,916 words) - 17:51, 18 July 2025
  • Thumbnail for RNA interference
    ribonucleic acid (RNA) molecules, microRNA (miRNA) and small interfering RNA (siRNA), are central to components to the RNAi pathway. Once mRNA is degraded,...
    140 KB (15,435 words) - 18:06, 31 July 2025
  • rasi/piRNA biogenesis.) Double-stranded RNAs capable of silencing repeat elements, then known as repeat associated small interfering RNA (rasiRNA), were...
    44 KB (5,243 words) - 05:19, 29 October 2024
  • Thumbnail for Telomerase
    means of interfering with telomerase in cancer cells. Most of the harmful cancer-related effects of telomerase are dependent on an intact RNA template...
    50 KB (5,791 words) - 07:29, 19 July 2025
  • example is RNA interference (RNAi), in which endogenously expressed microRNA (miRNA) or exogenously derived small interfering RNA (siRNA) induces the...
    48 KB (5,498 words) - 13:11, 28 December 2024
  • Inclisiran (category Small interfering RNA)
    and heterozygous familial hypercholesterolemia (HeFH). It is a small interfering RNA (siRNA) that acts as an inhibitor of a proprotein convertase, specifically...
    23 KB (1,937 words) - 11:44, 3 June 2025
  • levels. Using single-stranded RNA (ssRNA) fragments, such as microRNA (miRNA), or double-stranded small interfering RNA (siRNA), the complex functions as...
    36 KB (3,842 words) - 17:13, 25 November 2024
  • RNA polymerase IV (RNAP IV) is an enzyme that synthesizes small interfering RNA (siRNA) in plants, which silence gene expression. RNAP IV belongs to a...
    15 KB (1,820 words) - 15:32, 18 July 2025
  • Thumbnail for Messenger RNA
    triggers mRNA degradation by 5' decapping, 3' poly(A) tail removal, or endonucleolytic cleavage. In metazoans, small interfering RNAs (siRNAs) processed...
    52 KB (6,275 words) - 14:39, 28 July 2025
  • Trans-acting siRNA (abbreviated "ta-siRNA" or "tasiRNA") are a class of small interfering RNA (siRNA) that repress gene expression through post-transcriptional...
    9 KB (1,153 words) - 05:22, 31 January 2024
  • and regulate RNA modification. It has been observed that small interfering RNA (siRNA) and micro RNA (miRNA) are generally used as target RNA sequences,...
    30 KB (3,629 words) - 22:56, 17 July 2025
  • Gene silencing (category RNA)
    by an enzyme called Dicer. These small fragments, which include small interfering RNAs (siRNA) and microRNA (miRNA), are approximately 21–23 nucleotides...
    49 KB (5,674 words) - 17:24, 16 July 2025
  • Thumbnail for Zilebesiran
    Zilebesiran (category Small interfering RNA)
    being evaluated for the treatment of high blood pressure. It is small interfering RNA that is administered subcutaneously twice annually to lower blood...
    7 KB (227 words) - 13:15, 21 January 2025
  • Lepodisiran (category Small interfering RNA)
    Lepodisiran (LY3819469) is a small interfering RNA that was developed to reduce lipoprotein(a) in people at risk of cardiovascular disease. It was developed...
    4 KB (208 words) - 15:45, 27 June 2025
  • Olpasiran (category Antisense RNA)
    Olpasiran (AMG890) is an experimental siRNA (short interfering RNA) therapy designed to lower the level of lipoprotein(a), which is believed to be a causal...
    2 KB (234 words) - 20:21, 28 June 2025
  • Thumbnail for Haemophilia B
    Antibodies Fitusiran: An investigational therapy that utilizes small interfering RNA (siRNA) technology to reduce antithrombin levels, thereby increasing...
    23 KB (2,535 words) - 23:00, 17 July 2025
  • Natural antisense short interfering RNA (natsiRNA) is a type of siRNA. They are endogenous RNA regulators which are between 21 and 24 nucleotides in length...
    3 KB (319 words) - 05:05, 31 January 2024
  • Thumbnail for RNA
    transfer RNA (tRNA), microRNA (miRNA), small interfering RNA (siRNA), small nucleolar RNA (snoRNAs), Piwi-interacting RNA (piRNA), tRNA-derived small RNA (tsRNA)...
    66 KB (7,680 words) - 17:02, 22 July 2025
  • Thumbnail for Patisiran
    Patisiran (category Small interfering RNA)
    is estimated to affect 50,000 people worldwide. It is the first small interfering RNA-based drug approved by the U.S. Food and Drug Administration (FDA)...
    15 KB (952 words) - 21:49, 29 May 2025
  • in vitro or in vivo. small interfering RNA (siRNA) small nuclear RNA (snRNA) small nucleolar RNA (snoRNA) A class of small RNA molecules whose primary...
    302 KB (26,849 words) - 21:18, 31 July 2025
  • Thumbnail for Arcturus Therapeutics
    nanoparticle RNA therapeutics for nucleic acid medicines including small interfering RNA (siRNA), messenger RNA (mRNA), gene editing RNA, DNA, antisense...
    19 KB (1,801 words) - 02:20, 29 June 2025
  • Thumbnail for Long non-coding RNA
    ncRNAs from small non-coding RNAs, such as microRNAs (miRNAs), small interfering RNAs (siRNAs), Piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs)...
    99 KB (10,625 words) - 11:19, 19 July 2025
  • Vutrisiran (category Small interfering RNA)
    adults. It is a double stranded small interfering RNA (siRNA; also called RNA interference or RNAi therapeutic) that interferes with the expression of the...
    26 KB (2,601 words) - 17:51, 28 July 2025
  • for the different types of RNA are listed and explained. List of cis-regulatory RNA elements RNA: Types of RNA Non-coding RNA Gribaldo S, Brochier-Armanet...
    20 KB (1,022 words) - 07:09, 12 July 2025
  • Thumbnail for RNA silencing suppressor p19
    double-stranded RNAs that function as small interfering RNA (siRNA) in the RNA silencing system. By sequestering siRNA, p19 suppresses RNA silencing and...
    11 KB (1,172 words) - 03:13, 29 January 2023
  • Thumbnail for Argonaute
    Argonaute (category RNA-binding proteins)
    as RNA interference (RNAi). Argonaute proteins bind different classes of small non-coding RNAs, including microRNAs (miRNAs), small interfering RNAs (siRNAs)...
    17 KB (2,024 words) - 13:42, 17 July 2025
  • Thumbnail for MicroRNA
    the mRNA. miRNAs resemble the small interfering RNAs (siRNAs) of the RNA interference (RNAi) pathway, except miRNAs derive from regions of RNA transcripts...
    147 KB (16,651 words) - 18:23, 28 July 2025
  • the gene silencing typically associated with small interfering RNAs (siRNAs) in RNA interference. saRNAs offer a novel approach to upregulate genes of...
    19 KB (2,085 words) - 17:08, 23 July 2025
  • Thumbnail for Nucleic acid
    Nucleic acid (redirect from DNA and RNA)
    biological nucleic acid molecules range in size from 21 nucleotides (small interfering RNA) to large chromosomes (human chromosome 1 is a single molecule that...
    24 KB (2,848 words) - 22:04, 15 July 2025