The solute carrier family 18 member 2 (SLC18A2) also known as vesicular monoamine transporter 2 (VMAT2) is a protein that in humans is encoded by the...
29 KB (3,347 words) - 14:46, 25 May 2025
The vesicular monoamine transporter (VMAT) is a transport protein integrated into the membranes of synaptic vesicles of presynaptic neurons. It transports...
43 KB (4,993 words) - 04:26, 10 March 2025
Phenethylamine (redirect from 2-phenylethylamin)
amine-associated receptor 1 (TAAR1) and inhibiting vesicular monoamine transporter 2 (VMAT2) in monoamine neurons. To a lesser extent, it also acts as a neurotransmitter...
56 KB (5,429 words) - 21:17, 19 June 2025
Monoamine transporters (MATs) are proteins that function as integral plasma-membrane transporters to regulate concentrations of extracellular monoamine...
21 KB (2,342 words) - 15:34, 14 September 2024
Vesicular monoamine transporter 1 (VMAT1), also known as chromaffin granule amine transporter (CGAT) or solute carrier family 18 member 1 (SLC18A1), is...
16 KB (1,962 words) - 20:13, 1 May 2025
Deutetrabenazine (category Monoamine-depleting agents)
Deutetrabenazine (trade name Austedo) is a vesicular monoamine transporter 2 inhibitor which is used for the treatment of chorea associated with Huntington's...
10 KB (712 words) - 16:51, 25 May 2025
with human trace amine-associated receptor 1 (hTAAR1) and vesicular monoamine transporter 2 (VMAT2) in neurons. Dextroamphetamine is a more potent CNS...
63 KB (22,964 words) - 19:47, 17 June 2025
Dopaminergic (section Monoamine oxidase inhibitors)
For example, certain proteins such as the dopamine transporter (DAT), vesicular monoamine transporter 2 (VMAT2), and dopamine receptors can be classified...
28 KB (2,813 words) - 13:26, 17 June 2025
the direction of the vesicular monoamine transporter 2 (VMAT2), thereby additionally resulting in efflux of vesicular monoamine neurotransmitter into...
264 KB (22,158 words) - 03:06, 21 June 2025
inhibition of the serotonin transporter and PDE4. It promotes monoamine release through vesicular monoamine transporter-2 upregulation, with serotonin...
20 KB (2,126 words) - 10:15, 7 June 2025
"Novel N-1,2-dihydroxypropyl analogs of lobelane inhibit vesicular monoamine transporter-2 function and methamphetamine-evoked dopamine release". Journal...
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Reuptake inhibitor (redirect from Vesicular transporter blocker)
irreversible inhibitor of the vesicular monoamine transporter 2 (VMAT2), and is a prototypical example of a vesicular reuptake inhibitor. Two of the...
19 KB (1,917 words) - 07:07, 23 November 2024
is influenced by heredity and that a specific gene, called vesicular monoamine transporter 2 (VMAT2), predisposes humans towards spiritual or mystic experiences...
9 KB (1,046 words) - 17:46, 25 May 2025
Amphetamine (redirect from 1-Phenyl-2-Aminopropane)
of DAT, NET, trace amine-associated receptor 1 (TAAR1) and vesicular monoamine transporter 2 (SLC18A2), among other targets, therefore regulating the reuptake...
311 KB (32,780 words) - 19:16, 17 June 2025
which is a selective inhibitor of vesicular monoamine transporter 2 (VMAT2) also known as solute carrier family 18 member 2 (SLC18A2). VMAT2 is a protein...
22 KB (2,003 words) - 18:24, 19 June 2025
Phentermine (section Monoamine releasing agent)
amphetamines and MRAs, phentermine is completely inactive at the vesicular monoamine transporter 2 (VMAT2). Due to its actions on the catecholamines, phentermine...
44 KB (4,028 words) - 15:33, 30 May 2025
of DAT, NET, trace amine-associated receptor 1 (TAAR1) and vesicular monoamine transporter 2 (SLC18A2), among other targets, therefore regulating the reuptake...
84 KB (9,204 words) - 02:53, 2 June 2025
attenuates methamphetamine-induced changes in vesicular monoamine transporter 2 immunoreactivity and monoamine depletions in the striatum". The Journal of...
13 KB (1,257 words) - 00:43, 10 May 2025
Dextroamphetamine (redirect from (S)-1-phenylpropan-2-amine)
concentrations of the monoamine neurotransmitters and it releases these neurotransmitters from synaptic vesicles via vesicular monoamine transporter 2 (VMAT2). It...
66 KB (22,103 words) - 02:24, 2 June 2025
Valbenazine (category Monoamine-depleting agents)
medication used to treat tardive dyskinesia. It acts as a vesicular monoamine transporter 2 (VMAT2) inhibitor. Valbenazine is used to treat tardive dyskinesia...
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Tetrabenazine, deutetrabenazine, and valbenazine are all vesicular monoamine transporter 2 (VMAT2) inhibitors, which work by depleting dopamine in the...
144 KB (15,024 words) - 23:22, 17 June 2025
medications are used to treat tardive dyskinesia. These include the vesicular monoamine transporter 2 inhibitors tetrabenazine and deutetrabenazine. Extrapyramidal...
13 KB (1,359 words) - 06:00, 24 March 2024
human dopamine neurons, as both compounds induce efflux from vesicular monoamine transporter 2 (VMAT2) and activate TAAR1 with comparable efficacy. Like...
20 KB (2,301 words) - 06:14, 3 May 2025
Phenmetrazine (redirect from 2-Phenyl-3-methylmorpholine)
contrast to many other monoamine releasing agents (MRAs), phenmetrazine is inactive in terms of vesicular monoamine transporter 2 (VMAT2) actions. A few...
36 KB (3,428 words) - 10:46, 2 June 2025
MDMA (redirect from (RS)-1-(1,3-Benzodioxol-5-yl)-N-methylpropan-2-amine)
also acts on the vesicular monoamine transporter 2 (VMAT2) on synaptic vesicles to increase the cytosolic concentrations of the monoamine neurotransmitters...
240 KB (22,951 words) - 13:25, 14 June 2025
releasing agent (SNDRA). It has much less activity at the vesicular monoamine transporter 2 (VMAT2) than MDMA and may have less serotonergic neurotoxicity...
49 KB (4,251 words) - 06:25, 2 June 2025
serotonin transporter (SERT), and the norepinephrine transporter (NET) in the outer cell membrane and the vesicular monoamine transporter (VMAT1 and...
7 KB (1,409 words) - 21:17, 11 March 2024
Dopamine (redirect from 2-(3,4-dihydroxyphenyl)ethylamine)
small and large dense core vesicles by a solute carrier—a vesicular monoamine transporter, VMAT2. Dopamine is stored in these vesicles until it is ejected...
140 KB (14,357 words) - 03:16, 14 June 2025
Dysdiadochokinesia has been linked to a mutation in SLC18A2, which encodes vesicular monoamine transporter 2 (VMAT2). "dysdiadochokinesia". Merriam-Webster.com Dictionary...
6 KB (533 words) - 11:23, 12 July 2024
TAAR1 agonists and vesicular monoamine transporter 2 inhibitors that can enter monoamine neurons; this allows them to release monoamine neurotransmitters...
48 KB (15,358 words) - 02:43, 16 June 2025