DNA repair protein XRCC3 is a protein that in humans is encoded by the XRCC3 gene. This gene encodes a member of the RecA/Rad51-related protein family...
13 KB (1,745 words) - 09:33, 2 March 2025
including RAD51B (RAD51L1), RAD51C (RAD51L2), RAD51D (RAD51L3), XRCC2 and XRCC3. They each share about 25% amino acid sequence identity with RAD51 and each...
24 KB (2,984 words) - 09:42, 2 March 2025
frequently hypermethylated promoters; these genes are XRCC1, MLH3, PMS1, RAD51B, XRCC3, RAD54B, BRCA1, SHFM1, GEN1, FANCE, FAAP20, SPRTN, SETMAR, HUS1, and PER1...
51 KB (5,459 words) - 15:10, 5 April 2025
Albanes, Demetrius (2003). "Polymorphisms in the DNA repair genes XPD, XRCC1, XRCC3, and APE/ref-1, and the risk of lung cancer amongmale smokers in Finland"...
21 KB (2,529 words) - 20:56, 29 May 2025
hospital-based case-control histological studies of gene variants of both XRCC4 and XRCC3 and their possible association with risk for urothelial bladder cancer....
43 KB (5,681 words) - 00:50, 14 June 2024
genes have been identified: Rad51, Rad51L1/B, Rad51L2/C, Rad51L3/D, XRCC2, XRCC3, and DMC1/Lim15. All of these proteins, with the exception of meiosis-specific...
48 KB (5,526 words) - 19:40, 22 May 2025
Q9UBH6 18402 XRCC1 HGNC:12828 P18887 18403 XRCC2 HGNC:12829 O43543 18404 XRCC3 HGNC:12830 O43542 18405 XRCC4 HGNC:12831 Q13426 18406 XRCC5 HGNC:12833 P13010...
242 KB (17 words) - 18:43, 6 October 2024
N-terminal, and has two main functions: the prevention of t-loop excision by XRCC3, and the inhibition of SLX4. The final domain of TERF2 is called the hinge...
27 KB (3,340 words) - 22:06, 22 December 2023
next year, in separate reports, Jasin's group discovered that BRCA1 and XRCC3 are, respectively, required for and involved in homologous recombination...
12 KB (924 words) - 18:52, 24 September 2023
contributes to DNA double-strand break repair via the expression of Rad54B and XRCC3 genes". Biochemical Journal. 431 (2): 179–187. doi:10.1042/BJ20100988. ISSN 0264-6021...
15 KB (1,889 words) - 13:44, 16 September 2021
further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and...
9 KB (1,132 words) - 23:02, 21 October 2024
transcription (AIB1), to DNA damage response pathways (CHEK2, HRAS1, XRCC1, XRCC3, XRCC5). Sequence variants of these genes that are relatively common in...
92 KB (10,823 words) - 09:51, 26 January 2025
frequently hypermethylated promoters; these genes are XRCC1, MLH3, PMS1, RAD51B, XRCC3, RAD54B, BRCA1, SHFM1, GEN1, FANCE, FAAP20, SPRTN, SETMAR, HUS1, and PER1...
19 KB (2,390 words) - 22:58, 3 December 2023
Schild D (2002). "Interactions involving the Rad51 paralogs Rad51C and XRCC3 in human cells". Nucleic Acids Res. 30 (4): 1001–8. doi:10.1093/nar/30.4...
11 KB (1,334 words) - 11:51, 30 July 2024
including RAD51B (RAD51L1), RAD51C (RAD51L2), RAD51D (RAD51L3), XRCC2 and XRCC3. They each share about 25% amino acid sequence identity with RAD51 and each...
15 KB (1,849 words) - 09:37, 2 March 2025
Saxena, Sneha; Kaushal, Anjali; Nagaraju, Ganesh (1 February 2018). "RAD51C/XRCC3 Facilitates Mitochondrial DNA Replication and Maintains Integrity of the...
10 KB (798 words) - 11:10, 24 May 2025
1997). "Rare microsatellite polymorphisms in the DNA repair genes XRCC1, XRCC3 and XRCC5 associated with cancer in patients of varying radiosensitivity"...
23 KB (2,856 words) - 20:57, 6 March 2024
protein-protein interactions with UQCRC1, OPTN, ERCC8, GRINL1A, Dctn1, K8.1, XRCC3, PML, RAB7A, HNRNPA1L2, CDC73, NLRP3, HAUS2, TMEM248, and GOLT1B. GRCh38:...
6 KB (811 words) - 00:39, 2 September 2023