• Thumbnail for Beta thalassemia
    Beta-thalassemia (β-thalassemia) is an inherited blood disorder, a form of thalassemia resulting in variable outcomes ranging from clinically asymptomatic...
    35 KB (6,224 words) - 14:27, 9 May 2025
  • Alpha-thalassemia (α-thalassemia, α-thalassaemia) is an inherited blood disorder and a form of thalassemia. Thalassemias are a group of inherited blood...
    33 KB (4,411 words) - 08:38, 21 March 2025
  • Thumbnail for Thalassemia
    of hemoglobin, while beta thalassemia is a deficiency in the beta globin component. The severity of alpha and beta thalassemia depends on how many of the...
    75 KB (7,679 words) - 03:28, 23 April 2025
  • Thumbnail for Delta-beta thalassemia
    Delta-beta thalassemia is a rare form of thalassemia in which there is a reduced production of hemoglobin subunit delta and hemoglobin subunit beta and...
    8 KB (672 words) - 17:41, 28 January 2025
  • Thumbnail for Hemoglobin subunit beta
    haemoglobin. Beta thalassemia is an inherited genetic mutation in one (Beta thalassemia minor) or both (Beta thalassemia major) of the Beta globin alleles...
    19 KB (1,953 words) - 08:43, 5 April 2025
  • blood. Hemoglobin A2 may be increased in beta thalassemia or in people who are heterozygous for the beta thalassemia gene. HbA2 exists in small amounts in...
    9 KB (1,220 words) - 16:12, 24 September 2024
  • Thumbnail for Hemoglobin A
    cardiovascular deformities that could lead to cardiac failure. Beta-thalassemia (β-thalassemia) is an inherited mutation of the β-globulin gene which causes...
    17 KB (2,067 words) - 20:33, 28 December 2024
  • Sickle cell-beta thalassemia is an inherited blood disorder. The disease may range in severity from being relatively benign and like sickle cell trait...
    4 KB (341 words) - 13:46, 21 March 2024
  • Thumbnail for Hemoglobinopathy
    variants are HbS, HbE and HbC. The main types of thalassemia are alpha-thalassemia and beta thalassemia. Hemoglobin is a protein containing iron that facilitates...
    27 KB (2,682 words) - 20:24, 14 March 2025
  • Thumbnail for Fetal hemoglobin
    adult forms of hemoglobin begin to be produced. Diseases such as beta thalassemias, which affect components of the adult hemoglobin, can delay this process...
    38 KB (4,538 words) - 10:54, 4 March 2025
  • Thumbnail for Transfusion-dependent anemia
    advice after experiencing symptoms of anemia. Beta-thalassemia is a genetic disease mostly caused by beta-globin gene mutations. Clinical diagnosis is...
    25 KB (2,854 words) - 16:14, 19 November 2024
  • for the treatment of sickle cell disease and transfusion-dependent beta thalassemia. It was developed by Vertex Pharmaceuticals and CRISPR Therapeutics...
    21 KB (1,480 words) - 00:48, 27 December 2024
  • Thumbnail for Anisopoikilocytosis
    to various anemias, most often; beta thalassemia major, a form of microcytic anemia. In β thalassemia major the beta hemoglobin chain is completely absent...
    2 KB (132 words) - 19:19, 1 December 2023
  • Thumbnail for Microcytic anemia
    alpha thalassemia or beta thalassemia, respectively. Diagnosis is made by DNA analysis for alpha thalassemia and hemoglobin electrophoresis for beta thalassemia...
    16 KB (1,710 words) - 10:01, 17 March 2025
  • Treatment of the inherited blood disorder thalassemia depends upon the level of severity. For mild forms of the condition, advice and counseling are often...
    41 KB (4,621 words) - 16:57, 13 January 2025
  • Thumbnail for Gene therapy
    in France with beta thalassemia major had been successfully treated. Beta thalassemia major is an inherited blood disease in which beta haemoglobin is...
    179 KB (18,470 words) - 23:16, 20 May 2025
  • Thumbnail for CRISPR gene editing
    approved for use in the United Kingdom, to cure sickle-cell disease and beta thalassemia. Casgevy was approved for use in the United States on December 8, 2023...
    176 KB (20,510 words) - 18:56, 14 May 2025
  • under the brand name Zynteglo, is a gene therapy for the treatment for beta thalassemia. It was developed by Bluebird Bio and was given breakthrough therapy...
    21 KB (1,463 words) - 07:11, 6 August 2024
  • said to be helpful in differentiating iron deficiency anemia from beta thalassemia trait. Mentzer Index = MCV (fL) RBC (millions/ μ L ) {\displaystyle...
    3 KB (315 words) - 04:40, 18 March 2025
  • commercialize medicines for various diseases including sickle cell disease, beta thalassemia, various cancers, type 1 diabetes, and cardiovascular diseases. The...
    11 KB (918 words) - 07:47, 12 February 2025
  • name Reblozyl, is a medication used for the treatment of anemia in beta thalassemia and myelodysplastic syndromes. The US Food and Drug Administration...
    12 KB (819 words) - 22:00, 28 April 2025
  • individuals born with sickle-cell disease and another severe blood disorder, beta-thalassemia. In 2019, Victoria Gray enrolled in a groundbreaking clinical trial...
    3 KB (319 words) - 04:58, 10 February 2024
  • Kalyan Mansukhbhai (2017). "Co-Inheritance of Haemoglobin D-Punjab and Beta Thalassemia - A Rare Variant". Journal of Clinical and Diagnostic Research. 11...
    32 KB (3,699 words) - 23:45, 22 March 2025
  • betibeglogene autotemcel (Zynteglo), which treats transfusion-dependent beta thalassemia (TDT), a rare genetic blood disorder, and has been approved for use...
    15 KB (1,408 words) - 21:01, 17 October 2024
  • Thumbnail for Vertex Pharmaceuticals
    transfusion-dependent beta thalassemia and from the European Medicines Agency for sickle cell disease and transfusion-dependent beta thalassemia. In 2016, the...
    42 KB (4,060 words) - 15:34, 26 March 2025
  • mutations, such as alpha thalassemia. Like in sickle cell anemia, there is no one mutation responsible for beta thalassemia; several mutations or combinations...
    37 KB (4,564 words) - 12:53, 24 April 2025
  • Thumbnail for Hepcidin
    with beta thalassemia also have low hepcidin levels. The observations led researchers to hypothesize that more iron is absorbed in beta thalassemia than...
    24 KB (2,599 words) - 11:02, 22 May 2025
  • Thumbnail for Hemoglobin electrophoresis
    levels are typically elevated in beta-thalassemia minor and hemoglobin F may be slightly increased. In beta-thalassemia major, hemoglobin A is decreased (or...
    5 KB (540 words) - 13:30, 12 July 2024
  • Thumbnail for Hemoglobin Lepore syndrome
    and hematological findings bear close resemblance to those of the beta-thalassemia trait; a blood disorder that reduces the production of the iron-containing...
    11 KB (1,230 words) - 02:11, 7 July 2024
  • "Hemolytic Anemia: Overview - eMedicine Hematology". Retrieved 2009-02-07. "Beta thalassemia". Genetics Home Reference. U.S. National Library of Medicine, NIH....
    70 KB (2,600 words) - 15:39, 12 May 2025