done mainly through its expression in the hippocampus and the amygdala. Studies supporting the role of CREB in cognition include those that knock out the...

melanogaster, in rats and in mice (see CREB in Molecular and Cellular Cognition). CREB is necessary for the late stage of long-term potentiation. CREB also has...

Molecular cellular cognition (MCC) is a branch of neuroscience that involves the study of cognitive processes with approaches that integrate molecular...

HJ, Wright PE (November 2002). "Cooperativity in transcription factor binding to the coactivator CREB-binding protein (CBP). The mixed lineage leukemia...

is upregulated by CREB, it could be hypothesized that due to tianeptine's central role in BDNF and neuronal plasticity, this CREB may be the transcription...

localizing it in the plasma membrane. AKT can have a number of downstream effects such as activating CREB, inhibiting p27, localizing FOXO in the cytoplasm...

experiences and the environment to produce individual differences in behaviour, cognition, personality, and mental health. Epigenetic gene regulation involves...

cAMP response element-binding protein (CREB). Phosphorylated CREB, together with its coactivators, p300 and CREB-binding protein (CBP) enhances the transcription...

which in turn activates various signal pathways that ultimately activate the ERK pathway which then modulates transcription factors like CREB. CREB then...

beneficial stimuli and minimizing contact with harmful stimuli. Reward cognition serves to increase the likelihood of survival and reproduction by causing...

levels in NAc postsynaptic elements where it activates CaMK (calcium/calmodulin protein kinases) signaling, which, in addition to phosphorylating CREB, also...

and fat accumulation in alcoholic fatty liver. Metadoxine may block the differentiation step of preadipocytes by inhibiting CREB phosphorylation and binding...

research at her institute and in her community. Some of Josselyn's early discoveries include discovering that CREB over-expression in the auditory thalamus increases...

protein (CREB), inducing CREB-mediated changes in gene expression. With chronic alcohol intake, consumption of ethanol similarly induces CREB phosphorylation...

in 2013 for his contributions to the molecular cellular cognition of memory, a field he pioneered with the publication of two articles in Science in 1992...

Neural Dynamics and Cognition. Priya Rajasethupathy grew up in Brockport, New York. She received her Bachelor of Arts degree in biology with a pre-medicine...

reward-sensitizing effect, CREB transcriptional activity decreases user's sensitivity to the rewarding effects of the substance. CREB transcription in the nucleus accumbens...

role in the conception, although it may be called on to help subdue a woman's unusually strong totem. In "Clan of the Cave Bear", two people, Creb and...

levels in NAc postsynaptic elements where it activates CaMK (calcium/calmodulin protein kinases) signaling, which, in addition to phosphorylating CREB, also...

The cAMP response element-binding protein (CREB) is a transcription factor which is believed to be important in consolidating short-term to long-term memories...

The cAMP response element-binding protein (CREB) is a transcription factor which is believed to be important in consolidating short- to long-term memories...

levels in NAc postsynaptic elements where it activates CaMK (calcium/calmodulin protein kinases) signaling, which, in addition to phosphorylating CREB, also...

cognition, the transcription factor cAMP response element-binding protein (CREB) Convergence and divergence between the transcriptional responses to Zika...

Sage JR, Shuman T, Anagnostaras SG (January 2014). "Psychostimulants and cognition: a continuum of behavioral and cognitive activation". Pharmacol. Rev....

transduction pathway are necessary for conditioning related plasticity. CREB is also necessary for conditioning related plasticity, and it may induce...

Academy of Science and Technology and co-director of the IBS Center for Cognition and Sociality with Changjoon Justin Lee. He is also serving as the 2025...

Capitani S (February 2001). "HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic...

upregulated by CREB, a protein thought to be involved with the development of drug addiction, and CART may be an important therapeutic target in the treatment...

wide range of functions in both the central nervous system (CNS) and also peripheral tissues. It is involved in mood, cognition, reward, learning, memory...

subtype-selective Tilorone. A-582941: partial agonist; activates ERK1/2 and CREB phosphorylation; enhances cognitive performance AR-R17779: full agonist,...