• Thumbnail for Chromosomal translocation
    two healthy pairs of chromosomes, one of each pair "sticks" and blends together homogeneously. Each type of chromosomal translocation can result in disorders...
    46 KB (4,503 words) - 05:23, 23 May 2025
  • Thumbnail for Robertsonian translocation
    Robertsonian translocation (ROB) is a chromosomal abnormality where the entire long arms of two different chromosomes become fused to each other. It is...
    13 KB (1,368 words) - 08:21, 25 May 2025
  • Thumbnail for Philadelphia chromosome
    mixed-phenotype acute leukemia. The chromosomal abnormality in the Philadelphia chromosome from the reciprocal translocation t(9;22)(q34;q11), is the result...
    52 KB (5,746 words) - 03:46, 31 May 2025
  • defined endpoints." By combining chromosomal translocation, chromosomal inversion, and chromosomal deletion, chromosome engineering has been shown to identify...
    3 KB (281 words) - 02:49, 29 September 2022
  • Thumbnail for Chronic myelogenous leukemia
    to a clear genetic abnormality, the chromosomal translocation known as the Philadelphia chromosome. This chromosomal abnormality is so named because it...
    34 KB (3,880 words) - 20:21, 29 May 2025
  • A chromosomal abnormality, chromosomal anomaly, chromosomal aberration, chromosomal mutation, or chromosomal disorder is a missing, extra, or irregular...
    43 KB (4,583 words) - 11:56, 25 May 2025
  • Thumbnail for B-cell lymphoma
    Küppers, R; Dalla-Favera, R (10 September 2001). "Mechanisms of chromosomal translocations in B cell lymphomas" (PDF). Oncogene. 20 (40): 5580–94. doi:10...
    11 KB (975 words) - 14:43, 5 December 2024
  • Look up translocation in Wiktionary, the free dictionary. Translocation may refer to: Chromosomal translocation, a chromosome abnormality caused by rearrangement...
    771 bytes (132 words) - 23:51, 4 January 2022
  • chromosomal translocation between what were once identical chromosomes in pair 1, or by these chromosomes historically functioning as sex chromosomes...
    18 KB (2,268 words) - 03:33, 27 May 2025
  • Thumbnail for Eosinophilia
    syndrome. These include gene mutations in JAK2, ABL1, and FLT2 and chromosomal translocations that create the ETV6-ACSL6 fusion gene. Chronic eosinophilic leukemia...
    50 KB (5,526 words) - 11:15, 30 May 2025
  • Thumbnail for Sarcoma
    Ewing sarcoma are associated with a chromosomal translocation in which part of chromosome 11 fuses with part of chromosome 22. This results in the EWSR1 gene...
    37 KB (4,140 words) - 20:59, 6 May 2025
  • Thumbnail for Acute promyelocytic leukemia
    called promyelocytes. The disease is characterized by a t(15;17) chromosomal translocation involving the retinoic acid receptor alpha (RARA) gene and is...
    33 KB (3,500 words) - 20:36, 20 March 2025
  • Thumbnail for Fusion protein
    mutant proteins occur naturally when a complex mutation, such as a chromosomal translocation, tandem duplication, or retrotransposition creates a novel coding...
    19 KB (2,305 words) - 05:22, 15 May 2024
  • Thumbnail for Mantle cell lymphoma
    aggressive course of MCL. Chromosomal assessment using fluorescence in situ hybridization shows the characteristic chromosomal translocation t(11;14)(q13;q32)...
    43 KB (4,654 words) - 21:25, 29 May 2025
  • result of a chromosomal translocation or chromosomal inversion. In a translocation, genetic material is transferred from one chromosome to another, either...
    5 KB (528 words) - 17:44, 13 January 2024
  • Emanuel syndrome (category Chromosomal abnormalities)
    constitutional chromosomal translocation t(11;22)(q23;q11), owing to a 3:1 meiotic malsegregation event resulting in partial trisomy of chromosomes 11 and 22...
    9 KB (816 words) - 18:13, 25 March 2024
  • Thumbnail for Janet Rowley
    American human geneticist and the first scientist to identify a chromosomal translocation as the cause of leukemia and other cancers, thus proving that...
    18 KB (1,699 words) - 12:02, 23 March 2025
  • Thumbnail for Karyotype
    Karyotype (redirect from Chromosome banding)
    These differences probably came about through translocations. Differences in relative size of chromosomes. These differences probably arose from segmental...
    59 KB (7,006 words) - 17:53, 23 May 2025
  • Thumbnail for Multiple myeloma
    overproduction.[citation needed] A chromosomal translocation between the immunoglobulin heavy chain gene (on chromosome 14, locus q32) and an oncogene (often...
    129 KB (13,217 words) - 21:35, 29 May 2025
  • Thumbnail for Oncogene
    type of chromosome abnormality), resulting in an increased amount of protein in the cell A chromosomal translocation (another type of chromosome abnormality)...
    28 KB (3,162 words) - 09:06, 29 May 2025
  • Thumbnail for T(11:14)
    is a chromosomal translocation which essentially always involves the immunoglobulin heavy locus, also known as IGH in the q32 region of chromosome 14,...
    3 KB (322 words) - 04:39, 30 December 2024
  • Thumbnail for Acute myeloid leukemia
    people with AML; the types of chromosomal abnormalities often have prognostic significance. The chromosomal translocations encode abnormal fusion proteins...
    79 KB (7,941 words) - 23:40, 12 May 2025
  • Thumbnail for Sex chromosome
    their chromosomal arms. The 23rd pair of chromosomes are called allosomes. These consist of two X chromosomes in females, and an X chromosome and a Y...
    31 KB (3,693 words) - 04:20, 4 February 2025
  • to form through chromosomal inversions, which are rotations in regions of a chromosome due to chromosomal breakages or intra-chromosomal recombinations...
    13 KB (1,347 words) - 07:43, 23 April 2025
  • Thumbnail for Y chromosome
    (STR) Y linkage Y-chromosomal Aaron Y-chromosomal Adam Y-chromosome haplogroups in populations of the world "Homo sapiens Y chromosome genes". CCDS Release...
    81 KB (8,045 words) - 12:04, 1 June 2025
  • Thumbnail for Cytogenetics
    characterized by an acquired chromosomal abnormality, whose prognostic value is crucial. The identification of these chromosomal abnormalities has led to...
    26 KB (2,925 words) - 17:05, 12 January 2025
  • Thumbnail for Minimal residual disease
    as a way of measuring MRD in leukemias that do not contain a chromosomal translocation or other leukemic specific marker. In this case, the leukemic-specific...
    30 KB (3,699 words) - 23:29, 30 May 2025
  • Thumbnail for Chromosome
    little to no effect. Some chromosome abnormalities do not cause disease in carriers, such as translocations, or chromosomal inversions, although they...
    64 KB (6,606 words) - 06:59, 2 June 2025
  • of white and red sectors. These phenotypes are often due to a chromosomal translocation such that the color gene is now close to a region of heterochromatin...
    2 KB (253 words) - 12:45, 22 October 2021
  • Thumbnail for Genetics of Down syndrome
    meiosis, the chromosomal arrangement interferes with normal separation of chromosomes. Possible gametic arrangements are (see translocation karyotype figure):...
    9 KB (1,068 words) - 04:24, 25 June 2024