• Thumbnail for DNA binding site
    DNA binding sites are a type of binding site found in DNA where other molecules may bind. DNA binding sites are distinct from other binding sites in that...
    21 KB (2,176 words) - 21:02, 17 August 2024
  • Thumbnail for DNA-binding protein
    DNA-binding proteins are proteins that have DNA-binding domains and thus have a specific or general affinity for single- or double-stranded DNA. Sequence-specific...
    22 KB (2,637 words) - 06:01, 3 April 2025
  • Thumbnail for Transcription factor
    sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific...
    75 KB (8,351 words) - 22:53, 24 June 2025
  • Thumbnail for Transcription (biology)
    about half of EGR1 binding sites are located in promoters and half in enhancers. The binding of EGR1 to its target DNA binding site is insensitive to cytosine...
    58 KB (6,898 words) - 13:44, 24 May 2025
  • Thumbnail for RNA polymerase
    mediator complex must be attached to a DNA binding site called a promoter region before RNAP can initiate the DNA unwinding at that position. RNAP not only...
    43 KB (5,109 words) - 13:53, 25 June 2025
  • is an enzyme that cleaves DNA into fragments at or near specific recognition sites within molecules known as restriction sites. Restriction enzymes are...
    55 KB (5,856 words) - 08:25, 13 May 2025
  • noncovalent binding of DnaG to the DnaB helicase protein. The zinc-binding domain, the domain responsible for recognizing sequence specific DNA binding sites, is...
    20 KB (2,544 words) - 14:58, 5 November 2024
  • single-stranded DNA. A DBD can recognize a specific DNA sequence (a recognition sequence) or have a general affinity to DNA. Some DNA-binding domains may...
    20 KB (2,348 words) - 08:23, 1 June 2025
  • Thumbnail for Single-stranded binding protein
    two-subunit DNA polymerase, a Helicase-primase complex and a single-stranded DNA-binding protein. The human herpesvirus 1 (HHV-1) single-strand DNA-binding protein...
    10 KB (1,016 words) - 04:21, 25 August 2024
  • Thumbnail for TAR DNA-binding protein 43
    Transactive response DNA binding protein 43 kDa (TAR DNA-binding protein 43 or TDP-43) is a protein that in humans is encoded by the TARDBP gene. TDP-43...
    40 KB (4,560 words) - 00:13, 27 May 2025
  • Thumbnail for Zinc finger
    to the CpG site. It is used in mammals for antiviral defense. Various protein engineering techniques can be used to alter the DNA-binding specificity...
    42 KB (4,897 words) - 15:55, 24 May 2025
  • Thumbnail for DNA
    articles) DNA binding site prediction on protein DNA the Double Helix Game From the official Nobel Prize web site DNA under electron microscope Dolan DNA Learning...
    169 KB (18,027 words) - 17:07, 21 June 2025
  • A ribosome binding site, or ribosomal binding site (RBS), is a sequence of nucleotides upstream of the start codon of an mRNA transcript that is responsible...
    12 KB (1,413 words) - 00:17, 20 June 2025
  • CUT&RUN sequencing (category DNA sequencing)
    DNA sequencing to identify the binding sites of DNA-associated proteins. It can be used to map global DNA binding sites precisely for any protein of interest...
    16 KB (2,049 words) - 05:08, 2 June 2025
  • Thumbnail for Sequence logo
    create sequence logos, related DNA, RNA or protein sequences, or DNA sequences that have common conserved binding sites, are aligned so that the most conserved...
    8 KB (994 words) - 20:47, 29 June 2024
  • ChIP sequencing (category DNA)
    interactions with DNA. ChIP-seq combines chromatin immunoprecipitation (ChIP) with massively parallel DNA sequencing to identify the binding sites of DNA-associated...
    27 KB (3,353 words) - 03:17, 31 July 2024
  • Thumbnail for Origin of replication
    conserved DNA repeats that are specifically recognized by DnaA (called DnaA-boxes), an AT-rich DNA unwinding element (DUE), and binding sites for proteins...
    113 KB (12,563 words) - 21:58, 15 June 2025
  • Thumbnail for Promoter (genetics)
    gene. Promoters contain specific DNA sequences such as response elements that provide a secure initial binding site for RNA polymerase and for proteins...
    55 KB (6,390 words) - 11:11, 2 June 2025
  • to occur. Most activators are DNA-binding proteins that bind to enhancers or promoter-proximal elements. The DNA site bound by the activator is referred...
    17 KB (1,959 words) - 01:17, 24 May 2025
  • Thumbnail for Binding site
    molecular biology, a binding site is a region on a macromolecule such as a protein that binds to another molecule with specificity. The binding partner of the...
    28 KB (3,147 words) - 19:04, 13 January 2025
  • Selection and amplification binding assay (SAAB) is a molecular biology technique typically used to find the DNA binding site for proteins. It was developed...
    6 KB (814 words) - 01:29, 14 June 2024
  • Thumbnail for Lac operon
    genes starts with the binding of the enzyme RNA polymerase (RNAP), a DNA-binding protein, which binds to a specific DNA binding site, the promoter, immediately...
    41 KB (5,253 words) - 08:03, 25 May 2025
  • Thumbnail for DnaA
    DnaA binding to 9-mer (9-bp) repeats upstream of oriC. Binding of DnaA leads to strand separation at the 13-mer repeats. This binding causes the DNA to...
    34 KB (4,283 words) - 13:04, 23 May 2025
  • Thumbnail for Nucleosome
    intercalates into the DNA minor groove at all 14 sites where it faces the octamer surface. The distribution and strength of DNA-binding sites about the octamer...
    56 KB (6,666 words) - 13:34, 23 May 2025
  • of DNA-binding proteins and histone modifications. The application of ChIP-seq methods has reliably discovered transcription factor binding sites and...
    10 KB (750 words) - 20:06, 22 January 2024
  • protein bound to DNA often protects it from enzymatic cleavage. This makes it possible to locate a protein binding site on a particular DNA molecule. The...
    3 KB (364 words) - 10:38, 28 February 2025
  • target site that contain transcription factor binding sites. The original definition presented cis-regulatory modules as enhancers of cis-acting DNA, which...
    30 KB (3,472 words) - 02:52, 18 February 2024
  • Thumbnail for Bacterial DNA binding protein
    molecular biology, bacterial DNA binding proteins are a family of small, usually basic proteins of about 90 residues that bind DNA and are known as histone-like...
    19 KB (2,263 words) - 01:58, 11 December 2023
  • transcription factors, their DNA binding site motifs, and motif subtypes. Transcription factors (TFs) are proteins that bind DNA and thus regulate the transcription...
    6 KB (497 words) - 07:28, 28 May 2025
  • DNA adenine methyltransferase identification, often abbreviated DamID, is a molecular biology protocol used to map the binding sites of DNA- and chromatin-binding...
    18 KB (2,212 words) - 14:17, 26 April 2024