The angiotensin receptor blockers (ARBs), also called angiotensin (AT1) receptor antagonists or sartans, are a group of antihypertensive drugs that act...
35 KB (3,900 words) - 18:02, 3 February 2025
Renin inhibitor (redirect from Discovery and development of renin inhibitors)
renin–angiotensin–aldosterone system-interfering drugs such as angiotensin converting enzyme inhibitors (ACEIs), angiotensin receptor blockers (ARBs) and aldosterone...
45 KB (4,784 words) - 20:59, 24 November 2024
Beta blockers, also spelled β-blockers, are a class of medications that are predominantly used to manage abnormal heart rhythms (arrhythmia), and to protect...
75 KB (7,470 words) - 00:14, 23 May 2025
ACE inhibitor (redirect from Angiotensin converting enzyme inhibitor)
of taking it. In short, ACE inhibitors don't cure high ATII plasma levels. Angiotensin II receptor blocker Discovery and development of angiotensin receptor...
65 KB (7,182 words) - 03:29, 17 February 2025
too high. There are several types of drugs which include ACE inhibitors, angiotensin II receptor blockers (ARBs), and renin inhibitors that interrupt different...
22 KB (2,499 words) - 17:00, 21 May 2025
The action of AII itself is targeted by angiotensin II receptor antagonists, which directly block angiotensin II AT1 receptors. Angiotensin II is degraded...
29 KB (3,171 words) - 16:50, 15 May 2025
Candesartan (category Angiotensin II receptor antagonists)
Blopress Plus, Advantec and Ratacand Plus.[citation needed] In heart failure patients, angiotensin receptor blockers such as candesartan and valsartan may be...
25 KB (2,513 words) - 04:33, 14 May 2025
receptors (CBR) and prevents their activation by endocannabinoids. They include antagonists, inverse agonists, and antibodies of CBRs. The discovery of...
41 KB (4,204 words) - 20:10, 25 April 2025
Telmisartan (category Angiotensin II receptor antagonists)
recommended. It is an angiotensin II receptor blocker and works by blocking the effects of angiotensin II. Telmisartan was patented in 1991 and came into medical...
19 KB (1,699 words) - 20:43, 1 April 2025
control. The discovery and development of NK1 receptor antagonists have elicited antiemetic effect in both acute and especially in delayed phases of emesis...
29 KB (3,286 words) - 09:33, 2 March 2025
to as H2RAs and also called H2 blockers, are a class of medications that block the action of histamine at the histamine H2 receptors of the parietal...
21 KB (2,321 words) - 05:31, 19 May 2025
"Risk of pneumonia associated with use of angiotensin converting enzyme inhibitors and angiotensin receptor blockers: systematic review and meta-analysis"...
44 KB (5,225 words) - 09:01, 28 March 2025
Renin (category Hormones of the kidneys)
the body's renin-angiotensin-aldosterone system (RAAS)—also known as the renin-angiotensin-aldosterone axis—that increases the volume of extracellular fluid...
18 KB (2,102 words) - 07:19, 30 January 2025
types of neuromuscular-blocking drugs. Non-depolarizing blockers are reversed by acetylcholinesterase inhibitor drugs since non-depolarizing blockers are...
60 KB (6,872 words) - 07:06, 6 February 2025
Antihypertensive (redirect from Pharmacologic treatment of hypertension)
enzyme inhibitors (ACE inhibitors), angiotensin II receptor blockers or antagonists (ARBs), and beta blockers. Which type of medication to use initially for...
55 KB (6,272 words) - 21:47, 22 May 2025
Drug design (redirect from In silico drug discovery)
Acetylcholine receptor agonists Angiotensin receptor antagonists Bcr-Abl tyrosine-kinase inhibitors Cannabinoid receptor antagonists CCR5 receptor antagonists...
44 KB (5,022 words) - 12:47, 20 April 2025
Antihistamine (redirect from H1 receptor antagonist)
into these drugs led to the discovery that they were H1 receptor antagonists and also to the development of H2 receptor antagonists, where H1-antihistamines...
36 KB (3,300 words) - 13:08, 12 December 2024
Propranolol (category Beta blockers)
cardiovascular death, myocardial infarction, or stroke compared to an angiotensin receptor blocker was noted in one study. Propranolol is occasionally used to treat...
51 KB (4,699 words) - 05:15, 18 May 2025
Nicotinic agonist (redirect from Drug Discovery and Development: Nicotinic Acetylcholine Receptor Agonists)
of nicotinic acetylcholine receptor (nAChR) and their stimulation but until then the focus had mainly been on nicotine addiction. The development of nAChR...
43 KB (4,207 words) - 17:14, 3 February 2025
5-HT2A receptor is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and functions as a G protein-coupled receptor (GPCR)...
128 KB (13,435 words) - 03:57, 19 May 2025
Aldosterone (redirect from Receptors, aldosterone)
by blocking the angiotensin-converting enzyme (ACE), leading to lower aldosterone secretion. The net effect of these drugs is to reduce sodium and water...
32 KB (3,397 words) - 14:41, 25 March 2025
class of drugs that act as receptor antagonists at the 5-HT3 receptor, a subtype of serotonin receptor found in terminals of the vagus nerve and in certain...
43 KB (4,628 words) - 09:00, 16 April 2025
described; this led to the development of a number of other ACE inhibitors. More recently angiotensin receptor blockers and renin inhibitors have also...
20 KB (2,254 words) - 00:37, 19 January 2025
NMDA receptor antagonists are a class of drugs that work to antagonize, or inhibit the action of, the N-Methyl-D-aspartate receptor (NMDAR). They are commonly...
38 KB (4,196 words) - 10:43, 27 January 2025
glucocorticoid receptor modulators (SEGRMs) and selective glucocorticoid receptor agonists (SEGRAs) formerly known as dissociated glucocorticoid receptor agonists...
25 KB (2,554 words) - 22:25, 25 April 2025
H1 antagonist (redirect from H1-receptor antagonists)
H1 antagonists, also called H1 blockers, are a class of medications that block the action of histamine at the H1 receptor, helping to relieve allergic reactions...
23 KB (1,841 words) - 05:54, 18 May 2025
Forasartan (category Angiotensin II receptor antagonists)
potent than losartan. Discovery and development of angiotensin receptor blockers Bräse S, Banert K (2010). Organic Azides: Syntheses and Applications. New...
11 KB (943 words) - 12:45, 29 December 2023
Aliskiren (section Mechanism of action)
use of aliskiren with angiotensin receptor blockers (ARBs) or angiotensin-converting enzyme inhibitors (ACEIs) in patients with diabetes because of the...
13 KB (1,087 words) - 11:22, 3 June 2024
nicotinic receptor, also known as the α7 receptor, is a type of nicotinic acetylcholine receptor implicated in long-term memory, consisting entirely of α7 subunits...
28 KB (2,815 words) - 14:12, 9 May 2025
Bradykinin (section Receptors)
coupled receptor (GPCR) family. Bradykinin is also thought to be the cause of the dry cough in some patients on widely prescribed angiotensin-converting...
20 KB (2,007 words) - 22:27, 26 January 2025