The insulin-like growth factors (IGFs) are proteins with high sequence similarity to insulin. IGFs are part of a complex system that cells use to communicate...
14 KB (1,689 words) - 01:31, 19 August 2024
Insulin-like growth factor 1 (IGF-1), also called somatomedin C, is a hormone similar in molecular structure to insulin which plays an important role...
34 KB (4,512 words) - 06:26, 2 May 2025
Insulin-like growth factor 2 (IGF-2) is one of three protein hormones that share structural similarity to insulin. The MeSH definition reads: "A well-characterized...
15 KB (1,901 words) - 19:51, 2 April 2025
factors Insulin-like growth factor-1 (IGF-1) Insulin-like growth factor-2 (IGF-2) Interleukins IL-1- Cofactor for IL-3 and IL-6. Activates T cells. IL-2 – T-cell...
10 KB (1,131 words) - 18:45, 6 May 2025
Insulin-like growth factor 2 receptor (IGF2R), also called the cation-independent mannose-6-phosphate receptor (CI-MPR) is a protein that in humans is...
13 KB (1,664 words) - 16:27, 25 May 2024
The insulin-like growth factor-binding protein (IGFBP) serves as a transport protein for insulin-like growth factor 1 (IGF-1). Approximately 98% of IGF-1...
4 KB (468 words) - 09:09, 29 January 2023
The insulin-like growth factor 1 (IGF-1) receptor is a protein found on the surface of human cells. It is a transmembrane receptor that is activated by...
29 KB (3,603 words) - 16:26, 25 May 2024
Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. Human EGF is 6-kDa and has...
17 KB (1,716 words) - 11:48, 25 May 2025
Transforming growth factor ([attribution needed], or TGF) is used to describe two classes of polypeptide growth factors, TGFα and TGFβ. The name "Transforming...
6 KB (596 words) - 18:46, 25 May 2025
IGFBP3 (redirect from Insulin-like growth factor binding protein 3)
Insulin-like growth factor-binding protein 3, also known as IGFBP-3, is a protein that in humans is encoded by the IGFBP3 gene. IGFBP-3 is one of six IGF...
39 KB (4,717 words) - 13:09, 2 June 2024
growth factor 2 receptor (IGF-2R) Insulin-like growth factor Insulin-like growth factor 1 Insulin-like growth factor 2 Insulin-like growth factor-binding...
608 bytes (51 words) - 12:36, 21 February 2022
leading to cell division and cell migration. Epidermal growth factor Insulin-like growth factor 1 Epithelial–mesenchymal transition Madin-Darby Canine...
23 KB (2,623 words) - 08:53, 15 March 2025
Hepatocyte growth factor receptor (HGF receptor) is a protein that in humans is encoded by the MET gene. The protein possesses tyrosine kinase activity...
59 KB (6,731 words) - 05:32, 23 May 2025
IGFBP1 (redirect from Insulin-like growth factor binding protein 1)
Insulin-like growth factor-binding protein 1 (IBP-1) also known as placental protein 12 (PP12) is a protein that in humans is encoded by the IGFBP1 gene...
8 KB (1,045 words) - 09:28, 13 August 2023
Fibroblast growth factor 8 (FGF-8) is a protein that in humans is encoded by the FGF8 gene. The protein encoded by this gene belongs to the fibroblast growth factor...
21 KB (2,532 words) - 04:01, 24 May 2025
Platelet-derived growth factor receptors (PDGF-R) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF) family...
13 KB (1,563 words) - 09:00, 13 March 2024
Fibroblast growth factor 2 (FGF-2), also known as basic fibroblast growth factor (bFGF) and FGF-β, is a growth factor and signaling protein encoded by...
22 KB (2,698 words) - 15:56, 25 May 2025
Platelet-derived growth factor (PDGF) is one among numerous growth factors that regulate cell growth and division. In particular, PDGF plays a significant...
24 KB (2,882 words) - 15:04, 24 May 2025
VEGF receptor (redirect from Receptors, vascular endothelial growth factor)
are receptors for vascular endothelial growth factor (VEGF). There are three main subtypes of VEGFR, numbered 1, 2 and 3. Depending on alternative splicing...
8 KB (754 words) - 13:03, 18 September 2024
achondroplasia. The fibroblast growth factor receptors consist of an extracellular ligand domain composed of three immunoglobulin-like domains, a single transmembrane...
8 KB (827 words) - 14:53, 16 April 2025
Fibroblast growth factor 23 (FGF-23) is a protein and member of the fibroblast growth factor (FGF) family which participates in the regulation of phosphate...
16 KB (1,840 words) - 07:12, 2 November 2024
IGFBP7 (redirect from Insulin-like growth-factor binding protein 7)
Insulin-like growth factor-binding protein 7 is a protein that in humans is encoded by the IGFBP7 gene. The major function of the protein is the regulation...
20 KB (2,520 words) - 05:21, 20 May 2025
Vascular endothelial growth factor (VEGF, /vɛdʒˈɛf/), originally known as vascular permeability factor (VPF), is a signal protein produced by many cells...
40 KB (4,578 words) - 12:30, 10 September 2024
Fibroblast growth factor receptor 1 (FGFR-1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome...
44 KB (5,003 words) - 14:24, 24 February 2025
HER2 (redirect from Human epidermal growth factor receptor 2)
(human epidermal growth factor receptor 2) or CD340 (cluster of differentiation 340). HER2 is a member of the human epidermal growth factor receptor (HER/EGFR/ERBB)...
43 KB (4,665 words) - 03:55, 7 April 2025
Placental growth factor (PlGF) is a protein that in humans is encoded by the PGF gene. Placental growth factor is a member of the VEGF (vascular endothelial...
15 KB (1,867 words) - 09:38, 20 April 2025
Fibroblast growth factor receptor 3 (FGFR-3) is a protein that in humans is encoded by the FGFR3 gene. FGFR3 has also been designated as CD333 (cluster...
17 KB (1,844 words) - 17:02, 8 May 2025
description of compounds inhibiting the catalytic activity of the epidermal growth factor receptor (EGFR). The 1988 study was the first demonstration of a systematic...
10 KB (1,179 words) - 18:31, 8 August 2024
Fibroblast growth factor 21 (FGF-21) is a protein that in mammals is encoded by the FGF21 gene. The protein encoded by this gene is a member of the fibroblast...
24 KB (3,038 words) - 23:40, 29 November 2024
C-fos-induced growth factor (FIGF) (or vascular endothelial growth factor D, VEGF-D) is a vascular endothelial growth factor that in humans is encoded...
10 KB (1,253 words) - 05:14, 9 February 2024