• Low complexity regions (LCRs) in protein sequences, also defined in some contexts as compositionally biased regions (CBRs), are regions in protein sequences...
    30 KB (3,570 words) - 13:43, 22 May 2025
  • Computational methods can study protein sequences to identify regions with low complexity, which can have particular properties regarding their function...
    13 KB (926 words) - 13:30, 18 March 2025
  • Thumbnail for Palindromic sequence
    palindromes in peptides might be related to the prevalence of low-complexity regions in proteins, as palindromes are frequently associated with low-complexity sequences...
    7 KB (825 words) - 20:55, 9 December 2024
  • Thumbnail for Intrinsically disordered proteins
    and 33.0% of eukaryotic proteins, including certain disease-related proteins. Highly dynamic disordered regions of proteins have been linked to functionally...
    55 KB (6,383 words) - 21:33, 17 June 2025
  • Thumbnail for Glycine
    Glycine (category Multiple chemicals in an infobox that need indexing)
    C, Iliopoulos I, Promponas V, et al. (November 2019). "Low complexity regions in the proteins of prokaryotes perform important functional roles and are...
    41 KB (3,833 words) - 06:06, 18 June 2025
  • Thumbnail for Palindrome
    palindromes in peptides might be related to the prevalence of low-complexity regions in proteins, as palindromes frequently are associated with low-complexity sequences...
    47 KB (5,100 words) - 07:49, 19 June 2025
  • Thumbnail for Metal-binding protein
    histidine-rich low-complexity regions are found in metal-binding and especially nickel-cobalt binding proteins. These histidine-rich low complexity regions have...
    5 KB (500 words) - 02:41, 22 June 2024
  • Thumbnail for Amino acid
    example, lysine and arginine are present in large amounts in the low-complexity regions of nucleic-acid binding proteins. There are various hydrophobicity scales...
    94 KB (10,037 words) - 18:20, 18 June 2025
  • Thumbnail for Protein tandem repeats
    leucine-rich repeat proteins, which specifically bind some globular proteins by their concave surfaces; and zinc-finger proteins, which regulate the expression...
    17 KB (1,832 words) - 03:36, 2 June 2025
  • chases lasting up to 90 minutes to allow protein turnover to occur. In contrast, proteins that are expressed in mammalian cell lines tend to me more stable...
    8 KB (1,015 words) - 23:25, 26 May 2025
  • alignment is provided. FASTA can remove complexity regions before aligning the sequences by encoding low complexity regions in lower case and using the -S option...
    11 KB (1,464 words) - 18:53, 10 January 2025
  • Thumbnail for Dot plot (bioinformatics)
    the presence of low-complexity region/regions. Low-complexity regions are regions in the sequence with only a few amino acids, which in turn, causes redundancy...
    4 KB (544 words) - 00:23, 7 November 2024
  • Thumbnail for Protein structure prediction
    (PIR). A protein family comprises proteins with the same function in different organisms (orthologous sequences) but may also include proteins in the same...
    74 KB (9,238 words) - 19:32, 18 June 2025
  • Thumbnail for Protein isoform
    the human genome project and the large diversity of proteins seen in an organism: different proteins encoded by the same gene could increase the diversity...
    17 KB (2,010 words) - 02:30, 6 November 2024
  • sequences of proteins or the nucleotides of DNA and/or RNA sequences. A BLAST search enables a researcher to compare a subject protein or nucleotide...
    39 KB (4,974 words) - 03:38, 25 May 2025
  • transmembrane protein expressed in neurons. It contains up to seven potential transmembrane domains separated by regions of low complexity. Functionally...
    3 KB (266 words) - 18:09, 24 March 2025
  • Thumbnail for Failure to thrive
    physical growth in children. FTT is usually defined in terms of weight, and can be evaluated either by a low weight for the child's age, or by a low rate of increase...
    56 KB (5,308 words) - 02:23, 2 June 2025
  • The charge of proteins is determined by the pKa of its amino acid side chains, and the terminal amino acid and carboxylic acid. Proteins with isoelectric...
    43 KB (5,248 words) - 15:07, 23 May 2025
  • Thumbnail for Nucleic acid sequence
    specific proteins. The sequence of nucleobases on a nucleic acid strand is translated by cell machinery into a sequence of amino acids making up a protein strand...
    22 KB (2,409 words) - 19:05, 21 May 2025
  • Thumbnail for String cheese
    process aligns the proteins in the cheese, making it stringy. When mozzarella is heated to 60 °C (140 °F) and then stretched, the milk proteins line up. It is...
    9 KB (846 words) - 00:46, 15 May 2025
  • NV (1 January 2004). "Gaps in structurally similar proteins: towards improvement of multiple sequence alignment". Proteins. 54 (1): 71–87. doi:10.1002/prot...
    19 KB (2,483 words) - 14:32, 2 July 2024
  • Thumbnail for Proline-rich 12
    Proline-rich 12 (category Human proteins)
    PRR12 is rich in both proline and glycine. Many of the proline residues are positioned consecutively in regions of low complexity. These regions may give this...
    12 KB (1,304 words) - 03:20, 11 November 2024
  • Protein engineering is the process of developing useful or valuable proteins through the design and production of unnatural polypeptides, often by altering...
    58 KB (7,430 words) - 23:57, 9 June 2025
  • complex organisms – although the actual level of complexity is very hard to define or measure accurately in biology, with properties such as gene content...
    32 KB (3,735 words) - 16:50, 23 May 2025
  • relationship between proteins. Proteins with the same shapes but having little sequence or functional similarity are placed in different superfamilies...
    22 KB (2,564 words) - 19:34, 16 August 2024
  • biochemistry of protein domains of low sequence complexity that are now recognized to comprise ~25% of eukaryotic proteomes and to function broadly in eukaryotic...
    25 KB (2,881 words) - 05:13, 2 June 2025
  • demonstrated that non-secreted proteins were translated by free ribosomes in the cytosol, while secreted proteins (and target proteins, in general) were translated...
    53 KB (6,405 words) - 14:47, 8 June 2025
  • have relatively long low-complexity regions in their primary sequences and appear to have large intrinsically unstructured regions. Sae2 likely forms tetramers...
    4 KB (384 words) - 14:16, 17 September 2022
  • Thumbnail for Human genome
    genome. Human genomes include both protein-coding DNA sequences and various types of DNA that does not encode proteins. The latter is a diverse category...
    99 KB (10,091 words) - 18:43, 12 June 2025
  • Thumbnail for DNA annotation
    artificially high scores due to the presence of low complexity regions, and significant variation within a protein family. Functional annotation can be performed...
    66 KB (7,339 words) - 08:09, 11 November 2024