The mitochondrial permeability transition pore (mPTP or MPTP; also referred to as PTP, mTP, or MTP) is a protein pore complex that forms in the inner...
32 KB (3,472 words) - 23:00, 17 June 2025
shown that the compound inhibits mitochondrial permeability transition pore (MPTP) by inhibiting the activity of the pore regulator, cyclophilin D (CyP-D)...
6 KB (696 words) - 13:05, 10 November 2024
change of permeability is considered a cellular catastrophe, leading to cell death. However, brief mitochondrial permeability transition pore openings...
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Mitochondrion (redirect from Mitochondrial membrane)
hostile conditions. Anti-mitochondrial antibodies Mitochondrial metabolic rates Mitochondrial permeability transition pore Mitophagy Nebenkern Oncocyte...
172 KB (18,906 words) - 16:53, 20 June 2025
structural component of the mitochondrial permeability transition pore. The pore opening raises the permeability of the mitochondrial inner membrane, allows...
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protein, a liver protein linked to LDL release Mitochondrial permeability transition pore Mitochondrial trifunctional protein, a protein which catalyzes...
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an ischemic event is termed “reperfusion injury”. The mitochondrial permeability transition pore (mPTP) is normally closed during ischemia, but calcium...
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c-subunit has been indicated as a critical component of the mitochondrial permeability transition pore. ATPase, Vo complex, proteolipid subunit C, InterPro: IPR000245...
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the tissues. Examples of mitochondrial transport proteins include the following: The mitochondrial permeability transition pore, which opens in response...
30 KB (3,434 words) - 03:54, 2 December 2024
mitochondrial permeability transition pore (MPTP) and, thus, highly involved in mitochondrial metabolism and apoptosis, as well as in mitochondrial diseases...
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so-called mitochondrial permeability transition pore (MPT pore) in the mitochondrial membrane of cardiac cells. The opening of the MPT pore leads to the...
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pore to release of apoptogenic factors such as cytochrome c. However, VDAC are not essential components of the mitochondrial permeability transition pore...
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the mitochondrial electron transport chain leads to additional mitochondrial damage and opening of the mitochondrial permeability transition pore, which...
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important modulatory and possible structural component of the Mitochondrial Permeability Transition Pore, a channel involved in various pathologies whose function...
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Y (December 1998). "Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria"...
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The first involves the mitochondrial permeability transition pore (mPTP), which opens in response to elevated mitochondrial Ca2+ levels and oxidative...
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involved in regulation of the mitochondrial permeability transition pore (mPTP). Mutations in this gene can cause mitochondrial phosphate carrier deficiency...
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oxidative stress, p53 accumulates in the mitochondrial matrix and triggers mitochondrial permeability transition pore (PTP) opening. To the end of this, necrosis...
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excess calcium in the cytosol is the opening of the mitochondrial permeability transition pore, a pore in the membranes of mitochondria that opens when the...
25 KB (2,853 words) - 18:04, 18 June 2025
intermediates, and regulate cell death through activation of the mitochondrial permeability transition pore (mtPTP). When they fail, less and less energy is generated...
79 KB (8,674 words) - 10:08, 13 June 2025
internal membrane channel of the mitochondrial permeability transition pore, known as MPTP. Bongkrek acid is permeable through this membrane and binds...
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into mitochondria, which can prevent the opening of the mitochondrial permeability transition pore, it has been investigated as a therapeutic treatment for...
4 KB (328 words) - 15:33, 20 June 2022
suggests that activated BAX and/or Bak form an oligomeric pore, MAC in the MOM (mitochondrial outer membrane). This results in the release of cytochrome...
18 KB (2,092 words) - 13:58, 29 November 2024
response can be exploited for detecting the opening of the mitochondrial permeability transition pore (mPTP) and for measuring cell volume changes. Calcein...
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Mitochondrial outer membrane permeabilization (MOMP), also known as the mitochondrial outer membrane permeability, is one of two ways apoptosis (a type...
4 KB (478 words) - 23:32, 24 April 2025
ATP-sensitive potassium channel, the mitochondrial ATP-sensitive potassium channel, the mitochondrial permeability transition pore, reactive oxygen species generation...
10 KB (1,235 words) - 05:41, 26 May 2025
coupled with outer mitochondrial membrane destabilization that is opportunistically employed during the mitochondrial permeability transition. Mutations in...
21 KB (2,552 words) - 21:33, 5 June 2025
with the mitochondrial permeability transition pore (MPTP), a non-selective, high conductance channel spanning the inner and outer mitochondrial membrane...
23 KB (2,645 words) - 23:33, 27 May 2025
genetic control of necrosis-like cell death through the mitochondrial permeability transition pore". Molecular and Cellular Biology. 20 (15): 5454–68. doi:10...
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may refer to: Peak-to-peak, an amplitude of a signal Permeability transition pore, a mitochondrial channel protein complex Post-tetanic potentiation, a...
2 KB (248 words) - 06:34, 25 November 2024