Beta cells (β-cells) are specialized endocrine cells located within the pancreatic islets of Langerhans responsible for the production and release of insulin...
34 KB (3,924 words) - 20:59, 22 June 2025
Pancreatic beta cell function (synonyms Gβ or, if calculated from fasting concentrations of insulin and glucose, HOMA-Beta or SPINA-GBeta) is one of the...
17 KB (1,785 words) - 16:19, 6 November 2024
alpha cells which activates beta cells and delta cells. Somatostatin: inhibits alpha cells and beta cells. Also inhibits the secretion of pancreatic polypeptide...
24 KB (2,719 words) - 00:56, 30 July 2025
opposing view see review in ). Type 1 diabetes only occurs when pancreatic beta-cell function is impaired. Hyperinsulinemia can be seen in a variety of conditions...
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hepatectomy. Ursolic acid enhances the cellular immune system and pancreatic beta-cell function in streptozotocin-induced diabetic mice fed a high-fat diet...
17 KB (1,611 words) - 14:36, 26 July 2025
Congenital hyperinsulinism (redirect from Beta cell adenomatosis)
need for pancreatic enzyme supplements. Congenital hyperinsulinism (HI) has been referred to by a variety of names; nesidioblastosis and islet cell adenomatosis...
78 KB (7,819 words) - 04:01, 15 July 2025
Glucagon-like peptide-1 receptor (section Function)
endothelial function. Beta Cell Preservation: GLP-1 and its agonists have been found to exert protective effects on pancreatic beta cells, which are responsible...
33 KB (4,096 words) - 14:59, 28 June 2025
Neuroendocrine tumor (redirect from Functioning pancreatic endocrine tumor)
gastrointestinal tract and of the pancreatic islet cells, certain thymus and lung tumors, and medullary carcinoma of the parafollicular cells of the thyroid. Tumors...
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Pancreas (redirect from Pancreatic function)
the digestive system, it functions as an exocrine gland secreting pancreatic juice into the duodenum through the pancreatic duct. This juice contains...
51 KB (5,748 words) - 03:29, 25 May 2025
discover that alpha cells were histologically different than beta cells in 1907. Before the function of alpha cells was discovered, the function of their metabolic...
38 KB (3,984 words) - 03:43, 30 June 2025
SPINA-GBeta (category Static endocrine function tests)
is a calculated biomarker for pancreatic beta cell function. It represents the maximum amount of insulin that beta cells can produce per time-unit (e.g...
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Kerselaers, S.; et al. (31 March 2017). "Steviol glycosides enhance pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity"...
45 KB (4,186 words) - 23:29, 28 July 2025
Type 1 diabetes (section Alpha cell dysfunction)
occurs when the body's immune system destroys pancreatic cells (beta cells). In healthy persons, beta cells produce insulin. Insulin is a hormone required...
121 KB (14,237 words) - 02:13, 28 July 2025
sensitivity (SPINA-GR), which, if uncompensated by increased pancreatic beta cell function, can result in prediabetes and overt diabetes mellitus. Treatment...
62 KB (6,076 words) - 02:06, 19 July 2025
Pancreatic progenitor cells are multipotent stem cells originating from the developing fore-gut endoderm which have the ability to differentiate into the...
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Hypoglycemia (section Non-B cell tumors)
liver disease, hormone deficiency, tumors such as insulinomas or non-B cell tumors, inborn errors of metabolism, and several medications. Low blood sugar...
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into pancreatic islets. However, CD8+ cells have been shown to play an effector role, responsible for the ultimate destruction of islet beta cells. However...
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Pancreatic stellate cells (PaSCs) are classified as myofibroblast-like cells that are located in exocrine regions of the pancreas. PaSCs are mediated by...
21 KB (2,538 words) - 22:14, 19 January 2025
distinct functions, characteristics, and contributions to overall physiological processes. Cells may be classified by their physiological function, histology...
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Endocrine system (redirect from Endocrine cell)
pancreatic polypeptide. During the early stages of fetal development, the number of pancreatic alpha cells outnumbers the number of pancreatic beta cells...
39 KB (4,758 words) - 21:39, 15 July 2025
(January 2006). "The estrogenic effect of bisphenol A disrupts pancreatic beta-cell function in vivo and induces insulin resistance". Environmental Health...
101 KB (12,504 words) - 10:44, 12 July 2025
An insulinoma is a tumour of the pancreas that is derived from beta cells and secretes insulin. It is a rare form of a neuroendocrine tumour. Most insulinomas...
13 KB (1,375 words) - 17:37, 16 July 2025
Insulin resistance (section Static function tests)
shown to enhance cognitive development across various studies. Pancreatic beta cell function Chronic Somogyi rebound – Theoretical elevated blood sugar for...
60 KB (6,836 words) - 21:27, 29 July 2025
Delta cells (δ-cells or D cells) are somatostatin-producing cells. They can be found in the stomach, intestine and the pancreatic islets. Delta cells comprise...
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primary source of provitamin A, or the β cells in pancreatic islets, which produce insulin. The uppercase letter beta is not generally used as a symbol because...
13 KB (1,461 words) - 16:35, 23 July 2025
2 diabetes. Type 1 diabetes involves autoimmune destruction of pancreatic beta cells which create insulin. This occurs earlier in a person's life, leading...
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Digestive enzyme (redirect from Pancreatic enzymes)
health as its endocrine function. Two of the population of cells in the pancreatic tissue make up its digestive enzymes: Ductal cells: Mainly responsible...
20 KB (2,429 words) - 20:21, 17 July 2025
system. Insulin granules are a specific type of granule found in pancreatic beta cells. Insulin granules are secretory granules, which are responsible...
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Pancreatectomy (category Pancreatic cancer)
exocrine function. The pancreas is also made up of areas of cells known as pancreatic islets which include alpha, beta, and delta cells. Alpha cells secrete...
16 KB (1,718 words) - 22:05, 23 May 2025
et al. (2011-09-07). "Bace2 is a β cell-enriched protease that regulates pancreatic β cell function and mass". Cell Metabolism. 14 (3): 365–377. doi:10...
13 KB (1,479 words) - 15:48, 17 July 2025