• Thumbnail for Peroxisome proliferator-activated receptor
    field of molecular biology, the peroxisome proliferatoractivated receptors (PPARs) are a group of nuclear receptor proteins that function as transcription...
    18 KB (1,885 words) - 06:27, 15 April 2025
  • Thumbnail for Peroxisome proliferator-activated receptor alpha
    Peroxisome proliferator-activated receptor alpha (PPAR-α), also known as NR1C1 (nuclear receptor subfamily 1, group C, member 1), is a nuclear receptor...
    22 KB (2,602 words) - 18:54, 1 May 2025
  • Thumbnail for Peroxisome proliferator-activated receptor gamma
    Peroxisome proliferator-activated receptor gamma (PPAR-γ or PPARG), also known as the glitazone reverse insulin resistance receptor, or NR1C3 (nuclear...
    19 KB (2,091 words) - 16:26, 26 May 2025
  • Thumbnail for Peroxisome proliferator-activated receptor delta
    Peroxisome proliferator-activated receptor delta (PPAR-delta), or (PPAR-beta), also known as Nuclear hormone receptor 1 (NUC1) is a nuclear receptor that...
    18 KB (1,963 words) - 03:11, 2 June 2025
  • Thumbnail for PPAR agonist
    PPAR agonists are drugs which act upon the peroxisome proliferator-activated receptor. They are used for the treatment of symptoms of the metabolic syndrome...
    10 KB (1,227 words) - 21:57, 29 May 2025
  • proposed to be the peroxisome proliferator-activated receptor alpha (PPAR-α). PEA also has affinity to cannabinoid-like G-coupled receptors GPR55 and GPR119...
    47 KB (5,043 words) - 02:27, 2 June 2025
  • Thumbnail for GW501516
    expression of GLUT1 and SLC1A5. Acadesine GFT505 GW0742 Irisin Peroxisome proliferator-activated receptor Sodelglitazar SR9009 Koh B (2013-03-22). "Anti-doping...
    21 KB (2,027 words) - 03:42, 10 May 2025
  • Thumbnail for Pparg coactivator 1 alpha
    Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) is a protein that in humans is encoded by the PPARGC1A gene. PPARGC1A is...
    32 KB (3,869 words) - 08:16, 9 June 2025
  • Thumbnail for Telmisartan
    Telmisartan (category Angiotensin II receptor antagonists)
    from PPAR-γ. Telmisartan's activity at the peroxisome proliferator-activated receptor delta (PPAR-δ) receptor has prompted speculation around its potential...
    19 KB (1,702 words) - 19:58, 9 June 2025
  • Thumbnail for Thiazolidinedione
    Thiazolidinediones or TZDs act by activating PPARs (peroxisome proliferator-activated receptors), a group of nuclear receptors, specific for PPARγ (PPAR-gamma...
    20 KB (2,167 words) - 13:56, 24 May 2025
  • Thumbnail for Peroxisome
    filamentous fungi. Peroxisome proliferator-activated receptor Islinger M, Voelkl A, Fahimi HD, Schrader M (November 2018). "The peroxisome: an update on mysteries...
    33 KB (3,858 words) - 07:49, 22 April 2025
  • Another potential target of antiepileptic drugs is the peroxisome proliferator-activated receptor alpha. Some anticonvulsants have shown antiepileptogenic...
    71 KB (5,805 words) - 19:59, 29 May 2025
  • Thumbnail for Magnolia officinalis
    obesity by activating Peroxisome proliferator-activated receptor alpha/gamma to boost fat metabolism and energy use, and also enhance GABA_A receptor activity...
    6 KB (679 words) - 06:46, 19 May 2025
  • Thumbnail for Fibrate
    increased risk of rhabdomyolysis. Fibrates stimulate peroxisome proliferator activated receptor (PPAR) alpha, which controls the expression of gene products...
    10 KB (1,091 words) - 01:14, 8 October 2024
  • Thumbnail for 13-Hydroxyoctadecadienoic acid
    their 9-HODE counterparts) directly activate peroxisome proliferator-activated receptor gamma (PPARγ). This activation appears responsible for the ability...
    67 KB (7,853 words) - 21:38, 20 April 2025
  • Thumbnail for Farnesoid X receptor
    (January 2004). "Peroxisome proliferator-activated receptor-gamma coactivator 1alpha (PGC-1alpha) regulates triglyceride metabolism by activation of the nuclear...
    18 KB (2,072 words) - 23:27, 23 April 2025
  • Thumbnail for Partial agonist
    particular receptors include buspirone, aripiprazole, buprenorphine, nalmefene and norclozapine. Examples of ligands activating peroxisome proliferator-activated...
    4 KB (429 words) - 04:01, 14 February 2024
  • increasing the lipolysis in adipose tissue via activation of peroxisome proliferator-activated receptor-α. They decrease VLDL – very low density lipoprotein...
    47 KB (4,488 words) - 02:33, 25 May 2025
  • Thumbnail for 15-Hydroxyeicosatetraenoic acid
    and macrophages, detected in cystic fibrosis, and activate peroxisome proliferator-activated receptor-γ". Journal of Biological Chemistry. 287 (50): 41651–41666...
    67 KB (7,349 words) - 10:56, 9 June 2025
  • Thumbnail for GW0742
    Roberts-Thomson SJ (July 2004). "Effect of the peroxisome proliferator-activated receptor beta activator GW0742 in rat cultured cerebellar granule neurons"...
    9 KB (827 words) - 19:19, 6 May 2024
  • Thumbnail for Fatty liver disease
    "Molecular mechanisms of alcoholic fatty liver: role of peroxisome proliferator-activated receptor alpha". Alcohol. 34 (1): 35–8. doi:10.1016/j.alcohol.2004...
    38 KB (3,803 words) - 17:34, 20 June 2025
  • Thumbnail for Seladelpar
    used as the lysine dihydrate salt. It is a peroxisome proliferator-activated receptor delta (PPARδ) receptor agonist. The compound was licensed from Janssen...
    9 KB (563 words) - 22:08, 29 May 2025
  • Thumbnail for Ciglitazone
    (February 1996). "The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones"...
    6 KB (424 words) - 18:34, 28 May 2025
  • Thumbnail for Perfluorooctanoic acid
    German assessment notes that a 2005 study found PFOA to be genotoxic via a peroxisome proliferation pathway that produced oxygen radicals in HepG2 cells, and...
    125 KB (13,081 words) - 21:51, 12 June 2025
  • Thumbnail for Genistein
    Genistein (category Glycine receptor antagonists)
    the G protein-coupled estrogen receptor, and binds to and activates all three peroxisome proliferator-activated receptor isoforms, α, δ, and γ. Genistein...
    16 KB (1,473 words) - 21:27, 24 May 2025
  • Thumbnail for Pirinixic acid
    Pirinixic acid is a peroxisome proliferator-activated receptor alpha (PPARα) agonist that is under experimental investigation for prevention of severe...
    7 KB (675 words) - 00:08, 26 March 2025
  • Thumbnail for Acne
    inflammation by acting on the peroxisome proliferator-activated receptor alpha (PPARα) protein. PPARα increases the activity of activator protein 1 (AP-1) and...
    168 KB (18,257 words) - 19:51, 29 May 2025
  • Thumbnail for Ibuprofen
    cord injury. Another unusual activity is inhibition of the sweet taste receptor. After oral administration, peak serum concentration is reached after 1–2 hours...
    67 KB (6,236 words) - 17:44, 12 June 2025
  • Thumbnail for AMP-activated protein kinase
    by voluntary exercise. AMPK is required for increased peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) expression in skeletal muscle...
    65 KB (7,149 words) - 16:38, 9 June 2025
  • Thiazolidinediones (TZDs), also known as "glitazones," bind to PPARγ, peroxisome proliferator activated receptor γ, a type of nuclear regulatory protein involved in the...
    52 KB (5,601 words) - 20:35, 29 May 2025