Pore-forming proteins (PFTs, also known as pore-forming toxins) are usually produced by bacteria, and include a number of protein exotoxins but may also...

translocation, pore formation, endocytosis, and other biochemical processes. Anthrax is a disease caused by Bacillus anthracis, a spore-forming, Gram positive...

Perivitellin-2 (PV2) is a pore-forming toxin present in the egg perivitelline fluid of the apple snails Pomacea maculata (PmPV2) and Pomacea canaliculata...

Staphylococcus aureus and the first identified member of the pore forming beta-barrel toxin family. This toxin consists mostly of beta sheets (68%) with only about...

pore-forming toxins produced by Bacillus thuringiensis species of bacteria. They are useful for their insecticidal action and are the primary toxin produced...

β-pore-forming toxins. PVL is a bicomponent pore-forming toxin composed of LukS-PV and LukF-PV subunits. These assemble into octameric β-barrel pores on...

produces a pore forming toxin Neurotoxins primarily affect the nervous systems of animals. The group neurotoxins generally consists of ion channel toxins that...

Lysenin is a pore-forming toxin (PFT) present in the coelomic fluid of the earthworm Eisenia fetida. Pore-forming toxins are a group of proteins that...

The AB toxins are two-component protein complexes secreted by a number of pathogenic bacteria, though there is a pore-forming AB toxin found in the eggs...

the pores are formed, the pore forming cytolysins fall into two categories. Those forming pores with α-helices are named α-PFTs (Pore forming toxins). Those...

depending on the toxin) is formed and inserted into the target cell membrane. The presence of cholesterol in the target membrane is required for pore formation...

intestinal wall. They are mostly pore-forming toxins (mostly chloride pores), secreted by bacteria, that assemble to form pores in cell membranes. This causes...

sphingomyelin and ultimately caused cell lysis. γ-Hemolysins are pore-forming toxins in the same family as α-hemolysin. They are unique in that they come...

the ability to reproduce quickly producing toxins relating to the cause of diseases. The pore-forming toxin perfringolysin has the ability to cause gangrene...

cholesterol. It is related to streptolysin O and the θ-toxin of Clostridium perfringens. Cytolysins form pores in the cytoplasmic membrane that allows for the...

the channel-forming toxins and toxins that function as enzymes that act on the membrane. Most channel-forming toxins, which form pores in the target...

gangrene). C. septicum alpha toxin does, however, exhibit similarities to aerolysin, another beta-pore forming toxin. Alpha toxin and aerolysin share approximately...

called coelomocytes secrete a protein called lysenin, which is a pore-forming toxin, which is able to permeabilize and lyse invading cells. It is best...

smelled or tasted and cannot be destroyed by cooking. Rapid testing for this toxin in food is not standard. Some ciguatoxins lower the threshold for opening...

for toxin-receptor complex uptake into the cell. These tubules are essential for uptake into the host cell. The Shiga toxin (a non-pore forming toxin) is...

improve the environment for further fungal proliferation. The production of toxins depends on the surrounding intrinsic and extrinsic environments and these...

created by some types of bacteria (Staphylococcus). It is a type of pore-forming toxin. Leukocidins fall into the category of bacterial invasin. Invasins...

In molecular biology, aerolysin is a cytolytic pore-forming toxin exported by Aeromonas hydrophila, a Gram-negative bacterium associated with diarrhoeal...

ROMK1. Lq2 is also known as Potassium channel toxin alpha-KTx 1.2, Charybdotoxin-2, ChTX-Lq2, ChTx-d, Toxin 18-2 or Lqh 18-2. The name Lq2 refers to the...

Diphtheria toxin is an exotoxin secreted mainly by Corynebacterium diphtheriae but also by Corynebacterium ulcerans and Corynebacterium pseudotuberculosis...

homeostasis. This toxin (CPE) causes food poisoning. It alters intracellular claudin tight junctions in gut epithelial cells. This pore-forming toxin also can...

cells. No major enzymatic activities are associated. Instead, the toxin can form pores in the lipid membranes and induce Ca2+ ion flow. The onset of effects...

are vulnerable to this pore-forming activity varies among the toxins. The acylation of lysines is required for the pore-forming cytotoxic effects of all...

metabolizes to HT-2 mycotoxin (a major metabolite). The toxicity of T-2 toxin is due to its 12,13-epoxy ring. Epoxides are in general toxic compounds;...

novel pore-forming toxin of Escherichia coli, Salmonella typhi, and Shigella flexneri. HlyE is unrelated to the well characterised pore-forming E. coli...