Squalene monooxygenase (also called squalene epoxidase) is a eukaryotic enzyme that uses NADPH and diatomic oxygen to oxidize squalene to 2,3-oxidosqualene...
10 KB (1,146 words) - 01:30, 22 December 2023
Squalene is an organic compound. It is a triterpene with the formula C30H50. It is a colourless oil, although impure samples appear yellow. It was originally...
19 KB (1,793 words) - 09:46, 25 April 2025
2,3-Oxidosqualene (redirect from 2,3-squalene oxide)
cycloartenol, as well as saponins. It is formed when squalene is oxidized by the enzyme squalene monooxygenase. 2,3-Oxidosqualene is the substrate of various...
3 KB (97 words) - 06:26, 12 July 2024
Hopanoids (section Squalene synthesis)
reacts with squalene in a reaction catalyzed by squalene monooxygenase during sterol biosynthesis. Furthermore, squalene binds to squalene-hopene cyclases...
42 KB (4,595 words) - 07:38, 5 April 2025
transferred from eukaryotes. Sterol synthesis depends on two key enzymes: squalene monooxygenase and oxidosqualene cyclase. Phylogenetic analyses of oxidosqualene...
84 KB (8,672 words) - 05:14, 5 May 2025
List of EC numbers (EC 1) (section EC 1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases))
unspecific monooxygenase EC 1.14.1.2: now EC 1.14.13.9, kynurenine 3-monooxygenase EC 1.14.1.3: deleted, covered by EC 1.14.99.7, squalene monooxygenase and...
189 KB (24,619 words) - 20:16, 13 April 2025
biosynthesis starts with mevalonate to create squalene. Squalene monooxygenase in the next step oxidases the squalene and forms an epoxide resulting in 2,3-oxidosqualene...
12 KB (913 words) - 04:33, 12 January 2025
farnesyltransferase and squalene synthase (ERG9) and oxidation of NADPH to NADP+. This is then further oxygenated by the squalene monooxygenase (ERG1) to squalene 2,3-epoxide...
19 KB (1,916 words) - 09:50, 25 April 2025
reduction by NADPH to form squalene squalene synthase Squalene is oxidized to 2,3-oxidosqualene (squalene epoxide) squalene monooxygenase 2,3-Oxidosqualene is...
6 KB (305 words) - 03:31, 19 August 2024
cellular retinol-binding protein. The encoded protein stimulates squalene monooxygenase which is a downstream enzyme in metabolism of cholesterol. GRCh38:...
8 KB (932 words) - 17:25, 3 December 2023
prostaglandin-endoperoxide synthases MeSH D08.811.682.690.708.749 – squalene monooxygenase MeSH D08.811.682.690.708.783 – steroid hydroxylases MeSH D08.811...
158 KB (15,232 words) - 06:41, 8 March 2024
biosynthetic enzymes, thus the CPD gene encodes for the cytochrome P450 monooxygenase, which in the late C6 oxidation pathway oxidizes 6-deoxo-cathasterone...
15 KB (1,757 words) - 05:42, 12 March 2024
R)-tartaric acid derivatives. Detailed explanation of the mechanism of squalene epoxidase inhibition by terbinafine and elucidation of a fully atomic three-dimensional...
28 KB (2,981 words) - 12:55, 19 February 2025
also commonly known as cholesterol 24S-hydroxylase, cholesterol 24-monooxygenase, CYP46, or CYP46A1, is an enzyme that catalyzes the conversion of cholesterol...
19 KB (2,008 words) - 00:53, 15 January 2025
pathway, are derived from farnesyl diphosphate through intermediates like squalene and lanosterol, which are precursors to cholesterol and other steroid molecules...
116 KB (12,419 words) - 12:19, 7 May 2025
2.1.1.261: 4-dimethylallyltryptophan N-methyltransferase EC 2.1.1.262: squalene methyltransferase EC 2.1.1.263: botryococcene C-methyltransferase EC 2...
215 KB (21,664 words) - 05:19, 27 April 2025