5-hydroxytryptamine (serotonin) receptor 1D, also known as HTR1D, is a 5-HT receptor, but also denotes the human gene encoding it. 5-HT1D acts on the...

5-HT1D receptor agonists are pharmaceutical drugs for the treatment of migraine. They include: Triptans (which additionally act as 5-HT1B receptor agonists)...

eletriptan, frovatriptan and rizatriptan) are also agonists at the 5-HT1D receptor, which contributes to their antimigraine effect caused by vasoconstriction...

5-HT1B, 5-HT1D and 5-HT1F receptors. 5-HT1B are found in meningeal arteries, agonism of 5-HT1B causes vasoconstriction in cranial nerves. The 5-HT1D receptors...

including 5-HT1A, 5-HT1B, 5-HT1D, 5-HT1E, and 5-HT1F. Receptors of the 5-HT1 type, specifically, the 5-HT1A and 5-HT1D receptor subtypes, are present on...

pressure, and dry mouth. The drug acts as a selective serotonin 5-HT1B and 5-HT1D receptor agonist. Structurally, it is a triptan and a tryptamine derivative...

pain. The drugs of this class act as agonists for serotonin 5-HT1B and 5-HT1D receptors at blood vessels and nerve endings in the brain. The first clinically...

which activates 5-HT1A, 5-HT1D, 5-HT1B, D2 and norepinephrine receptors. LSD (a psychedelic) is a 5-HT1A, 5-HT2A, 5-HT2C, 5-HT5A and 5-HT6 agonist. The...

Activation of these receptors results in vasoconstriction. The high distribution of vasoconstrictive 5-HT1B and 5-HT1D receptors around the brain makes...

generally occur within three hours. Its primary effect as a serotonin 5-HT1B/5-HT1D receptor agonist can create common side effects such as chest pressure, fatigue...

receptor agonist and 5-HT1A and 5-HT1D receptor agonist [5] Sunobinop (IMB-115, IT-1315, S-117957, V-117957) – nociceptin receptor agonist [6][7] ALKS-2680...

GR-55562 is a selective serotonin 5-HT1B and 5-HT1D receptor antagonist. It is one of several selective serotonin 5-HT1B receptor antagonists used in scientific...

antagonist for the serotonin receptor subtype 5-HT1D, with around 60x selectivity over other related receptors. The 5-HT1D receptor has a very similar pharmacology...

Alniditan is a 5-HT1D receptor agonist with migraine-preventive effects. The sizeable number of serotonergic drugs for treating migraines all incorporate...

5-HT5A, and H1 receptors, a full or near-full agonist of the 5-HT1A, 5-HT1B, and 5-HT1D receptors, and a silent antagonist of the 5-HT2B receptor and...

Maroteaux L (Oct 1994). "The human serotonin 5-HT2B receptor: pharmacological link between 5-HT2 and 5-HT1D receptors". FEBS Letters. 352 (3): 393–9. Bibcode:1994FEBSL...

5-Benzyloxytryptamine (5-BT), is a tryptamine derivative which acts as an agonist at the 5-HT1D, 5-HT2 and 5-HT6 serotonin receptors, and an antagonist...

The 5-HT2A receptor is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and functions as a G protein-coupled receptor (GPCR)...

acts as a 5-HT1B and 5-HT1D receptor agonist. Donitriptan Saxena PR, De Vries P, Wang W, et al. (February 1997). "Effects of avitriptan, a new 5-HT 1B/1D...

serotonin 5-HT1B receptor, 7,100 nM for the serotonin 5-HT1A receptor, and >10,000 nM for the serotonin 5-HT1D receptor, whereas other serotonin receptors were...

is mediated by 5-HT1D receptors, whereas the vasoconstriction effect involves 5-HT2 receptor activation. YM-348 is a highly selective 5-HT2C agonist and...

receptor (or 5-HT1A receptor) is a subtype of serotonin receptors, or 5-HT receptors, that binds serotonin, also known as 5-HT, a neurotransmitter. 5-HT1A...

identified as serotonin 5-HT1D receptor ligands, serotonin 5-HT6 receptor partial agonists, and/or serotonin 5-HT7 receptor inverse agonists. These actions...

NMDA receptor antagonist FKB-01MD (FKB01MD; TGBA-01AD; TGBA01AD) – serotonin reuptake inhibitor, serotonin 5-HT1A receptor agonist, serotonin 5-HT1D receptor...

somewhat selective 5-HT1D agonist, with a 10-fold greater affinity for the 5-HT1B receptor, and 25-fold greater affinity for the 5-HT1A receptor. When L-694247...

000-fold higher affinity for the serotonin 5-HT1A receptor over the serotonin 5-HT2A receptor. In relation to this, 5-MeO-DMT has been described as an "atypical"...

The 5-HT2C receptor is a subtype of the 5-HT2 receptor that binds the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). Like all 5-HT2...

partial agonist of the serotonin 5-HT1A receptor (EC50 = 2,300 nM; Emax = 74.7%) and of the serotonin 5-HT1D receptor (EC50 = 262 nM; Emax = 57.1%). Conversely...

selectivity for this receptor over 12 other assessed targets, including the serotonin 5-HT1D, 5-HT2A, 5-HT2C, and 5-HT3 receptors among others (Ki = ≥380–4...

sumatriptan and metergoline at the human 5-HT1D beta receptor: further evidence for a role of the 5-HT1D receptor in the action of sumatriptan". European...