Anaphase-promoting complex (also called the cyclosome or APC/C) is an E3 ubiquitin ligase that marks target cell cycle proteins for degradation by the...

condensation in late anaphase, to help chromosome segregation and the re-formation of the nucleus. Anaphase starts when the anaphase promoting complex marks an inhibitory...

Maturation-promoting factor (abbreviated MPF, also called mitosis-promoting factor or M-Phase-promoting factor) is the cyclin–Cdk complex that was discovered...

with the anaphase-promoting complex, SCF has important roles in the ubiquitination of proteins involved in the cell cycle. The SCF complex also marks...

of this checkpoint is the stimulation of the anaphase-promoting complex by M-phase cyclin-CDK complexes, which in turn causes the proteolytic destruction...

Anaphase-promoting complex subunit 2 is an enzyme that in humans is encoded by the ANAPC2 gene. A large protein complex, termed the anaphase-promoting...

activate the anaphase promoting complex (APC/C), a large 11-13 subunit complex that initiates chromatid separation and entrance into anaphase. The APC/CCdc20...

(cdc20 homolog 1) is one of the substrate adaptor proteins of the anaphase-promoting complex (APC) in the budding yeast Saccharomyces cerevisiae. Functioning...

triggers the abrupt shift to anaphase. This abrupt shift is caused by the activation of the anaphase-promoting complex and its function of tagging degradation...

Anaphase-promoting complex subunit 7 is an enzyme that in humans is encoded by the ANAPC7 gene. Multiple transcript variants encoding different isoforms...

cohesin complex which links the sister chromatids together. Without Cdc20, the anaphase-promoting complex (APC) cannot become activated and anaphase is not...

The anaphase- promoting complex or cyclosome (APC/C) is a highly specific ubiquitin protein ligase responsible for triggering events of late mitosis....

progression to anaphase. Any unattached or improperly attached kinetochores generate signals that prevent the activation of the anaphase promoting complex (cyclosome...

assembly checkpoint inhibits the anaphase promoting complex. Normally, activation of the anaphase promoting complex leads to the separation of sister...

checkpoint complex (MCC). Thereby it inhibits the activity of the anaphase-promoting complex/cyclosome (APC/C). Homologues of Mad1 are conserved in eukaryotes...

Anaphase-promoting complex subunit 11 is an enzyme that in humans is encoded by the ANAPC11 gene. ANAPC11 has been shown to interact with ANAPC2 and CDC27...

facilitated by the anaphase-promoting complex (APC). CDK1 is regulated by cyclin B, whose synthesis peaks at the end of meiosis I. At anaphase I, cyclin B is...

domain called a TPR domain. Proteins with such domains include the anaphase-promoting complex (APC) subunits cdc16, cdc23 and cdc27, the NADPH oxidase subunit...

Anaphase-promoting complex subunit 4 is an enzyme that in humans is encoded by the ANAPC4 gene. A large protein complex, termed the anaphase-promoting...

Anaphase-promoting complex subunit 5 is an enzyme that in humans is encoded by the ANAPC5 gene. The anaphase-promoting complex (APC) consists of at least...

of anaphase, securin is dephosphorylated by Cdc14 and other phosphatases. Dephosphorylated securin is recognized by the Anaphase-Promoting Complex (APC)...

anaphase-promoting complex". Gene. 262 (1–2): 51–9. doi:10.1016/S0378-1119(00)00511-4. PMID 11179667. "Entrez Gene: ANAPC1 anaphase promoting complex...

prior to anaphase. Bub3 and its related proteins that form the Spindle Assembly Checkpoint (SAC) inhibit the action of the Anaphase Promoting Complex (APC)...

(or APC2), part of the Anaphase-promoting complex. CUL1, 2, 3, 4A, 4B, 5 and 7 each form part of a multi-subunit ubiquitin complex. Cullin-RING ubiquitin...

of anaphase-promoting complex (APC). This controls the rate of production of cyclin, and regulates cyclin levels and controls the S-phase-promoting factor...

in vitro biochemical characterisation of the activity of the anaphase-promoting complex (APC) and used cryo-EM to study the APC structure. Passmore worked...

transcription factors downregulate expression of S phase cyclin genes; anaphase-promoting complex (APC) is activated, which targets and degrades S and M cyclins...

regulator which ensures timely mitotic entry by primarily inhibiting Anaphase-Promoting Complex/Cyclosome (APC/C) activity. This protein is present in many organisms...

Bonni S; Wrana J L; Luo K (November 2001). "Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN". Genes Dev. 15 (21)...

plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation...