Arachidonate 5-lipoxygenase, also known as ALOX5, 5-lipoxygenase, 5-LOX, or 5-LO, is a non-heme iron-containing enzyme (EC 1.13.11.34) that in humans...
61 KB (7,553 words) - 16:29, 17 August 2024
are as follows: Arachidonate 5-lipoxygenase (ALOX5) (EC 1.13.11.34; InterPro: IPR001885), also termed 5-lipoxygenase, 5-LOX, and 5-LO. Major products:...
32 KB (3,886 words) - 12:01, 29 November 2024
Arachidonate 5-lipoxygenase inhibitors are compounds that slow or stop the action of the arachidonate 5-lipoxygenase (5-lipoxygenase or 5-LOX) enzyme...
11 KB (1,292 words) - 23:19, 22 January 2025
medication which functions as a leukotriene-related enzyme inhibitor (arachidonate 5-lipoxygenase) or leukotriene receptor antagonist (cysteinyl leukotriene receptors)...
10 KB (1,015 words) - 05:18, 11 April 2025
Arachidonate 5-lipoxygenase-activating protein also known as 5-lipoxygenase activating protein, or FLAP, is a protein that in humans is encoded by the...
14 KB (1,738 words) - 02:52, 16 December 2023
ALOX15 (redirect from Arachidonate 15-lipoxygenase-1)
ALOX15 (also termed arachidonate 15-lipoxygenase, 15-lipoxygenase-1, 15-LO-1, 15-LOX-1) is, like other lipoxygenases, a seminal enzyme in the metabolism...
44 KB (5,708 words) - 18:03, 29 November 2024
arachidonate-5-lipoxygenase, 5-lipoxygenase, 5-LO, and 5-LOX). ALOX5 metabolizes arachidonic acid to its hydroperoxide derivative, arachidonic acid 5-hydroperoxide...
48 KB (6,107 words) - 08:55, 31 December 2024
fatty acid found primarily in seed oils. When acting on GLA, arachidonate 5-lipoxygenase produces no leukotrienes and the conversion by the enzyme of...
10 KB (976 words) - 18:51, 15 September 2024
Leukotriene (redirect from Leukotriene-5)
essential fatty acid eicosapentaenoic acid (EPA) by the enzyme arachidonate 5-lipoxygenase. Leukotrienes use lipid signaling to convey information to either...
17 KB (1,895 words) - 16:42, 21 April 2025
ALOX12 (redirect from Arachidonate 12-lipoxygenase)
13.11.31), also known as arachidonate 12-lipoxygenase, 12-lipoxygenase, 12S-Lipoxygenase, 12-LOX, and 12S-LOX is a lipoxygenase-type enzyme that in humans...
32 KB (3,928 words) - 09:06, 1 September 2023
metabolized to the 3 double bond-containing analog of 5-HETE viz., 5-HETrE (see Arachidonate 5-lipoxygenase § Mead acid). Hydroxyeicosatetraenoic acids, leukotrienes...
86 KB (9,651 words) - 06:41, 2 November 2024
activated arachidonate 5-lipoxygenase (ALOX5) to form 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HpETE); c) reduction of this 5(S)-HpETE...
34 KB (4,378 words) - 00:56, 27 February 2025
agents which function as leukotriene-related enzyme inhibitors (arachidonate 5-lipoxygenase) or leukotriene receptor antagonists (cysteinyl leukotriene receptors)...
7 KB (816 words) - 17:47, 21 March 2025
co-localization of cytosolic phospholipase A2 (cPLA2), arachidonate 5-lipoxygenase (5-LO), 5-lipoxygenase-activating protein (FLAP) and LTC4 synthase (LTC4S)...
7 KB (563 words) - 02:22, 11 November 2023
metabolites of arachidonate 5-lipoxygenase (5-LOX): 5-hydroxyeicosatetraenoic acid (5-(S)-HETE), and its 5-keto analog 5-oxo-eicosatetraenoic acid (5-oxo-ETE)...
12 KB (1,777 words) - 01:49, 24 September 2024
Leukotriene A4 synthase may refer to: Arachidonate 5-lipoxygenase, an enzyme Arachidonate 12-lipoxygenase, an enzyme This set index page lists enzyme...
446 bytes (49 words) - 15:14, 5 February 2015
6817–9. PMID 12460891. Ghosh J, Myers CE (1998). "Inhibition of arachidonate 5-lipoxygenase triggers massive apoptosis in human prostate cancer cells". Proc...
26 KB (3,256 words) - 08:25, 23 December 2023
Arachidonic acid (redirect from Arachidonate acid)
'peanut', although peanut oil does not contain any arachidonic acid. Arachidonate is the name of the derived carboxylate anion (conjugate base of the acid)...
21 KB (1,886 words) - 23:50, 7 April 2025
Arachidonate 15-lipoxygenase type II is an enzyme that in humans is encoded by the ALOX15B gene. ALOX15B, also known as 15-lipoxygenase-2 (15-LO-2 or...
8 KB (1,036 words) - 02:50, 11 September 2022
protein Leukemia, acute lymphocytic, susceptibility to, 1 ALOX5: Arachidonate 5-Lipoxygenase (processes essential fatty acids to leukotrienes, which are important...
29 KB (1,977 words) - 08:58, 1 February 2025
Gab-1. Grb2 has been shown to interact with: ADAM15, Abl gene, Arachidonate 5-lipoxygenase, B-cell linker, BCAR1, BCR gene, Beta-2 adrenergic receptor,...
82 KB (9,365 words) - 09:44, 2 March 2025
responses to disturbances. In humans, arachidonate 12-lipoxygenase (12-LO, 12-LOX, ALO12, or platelet type 12-lipoxygenase) is encoded by the ALOX12 gene and...
63 KB (6,990 words) - 07:38, 5 February 2025
450 – lipoxygenase MeSH D12.776.556.579.374.450.025 – arachidonate lipoxygenases MeSH D12.776.556.579.374.450.025.020 – arachidonate 5-lipoxygenase MeSH D12...
133 KB (7,397 words) - 16:43, 9 February 2024
ethanol amide metabolites has not been reported. Arachidonate 5-lipoxygenase Arachidonate 15-lipoxygenase Leukotriene 15-Hydroxyicosatetraenoic acid Greene...
16 KB (1,853 words) - 07:49, 28 May 2024
Arachidonate 12-lipoxygenase, 12R type, also known as ALOX12B, 12R-LOX, and arachidonate lipoxygenase 3, is a lipoxygenase-type enzyme composed of 701...
13 KB (1,704 words) - 02:13, 17 June 2024
to montelukast, zafirlukast and pranlukast. Antileukotriene Arachidonate 5-lipoxygenase inhibitor Antihistamines Hooper NM (2013). Membrane dipeptidase...
19 KB (1,849 words) - 19:17, 27 March 2025
of Medicine. "Entrez Gene: ALOXE3 arachidonate lipoxygenase 3". Schneider C, Brash AR (August 2002). "Lipoxygenase-catalyzed formation of R-configuration...
20 KB (2,593 words) - 04:15, 27 February 2024
medications or herbal agents such as skull cap or green tea. Arachidonate 5-lipoxygenase "Flavocoxid". livertox.nlm.nih.gov. Archived from the original...
4 KB (556 words) - 13:52, 15 April 2024
Hartmut; Walther, Matthias; Kuban, Ralf Jürgen (2002). "Mammalian arachidonate 15-lipoxygenases". Prostaglandins & Other Lipid Mediators. 68–69: 263–290. doi:10...
67 KB (7,853 words) - 21:38, 20 April 2025
14Z-eicosatetraenoic acid) and concurrently the 11Z double bond in this arachidonate moves to the 10E position to form the intermediate product, 12S-hydroperoxy-5Z...
34 KB (3,965 words) - 03:36, 16 January 2025