• c-Met inhibitors are a class of small molecules that inhibit the enzymatic activity of the c-Met tyrosine kinase, the receptor of hepatocyte growth factor/scatter...
    32 KB (3,542 words) - 19:34, 2 July 2024
  • Thumbnail for Hepatocyte growth factor receptor
    of GRB2, phospholipase C γ (PLC-γ), p85, and SHP2. GAB1 is a key coordinator of the cellular responses to MET and binds the MET intracellular region with...
    59 KB (6,731 words) - 19:27, 17 March 2025
  • Thumbnail for Met Gala
    The Met Gala, formally called the Costume Institute Benefit, is the annual haute couture fundraising festival held for the benefit of the Metropolitan...
    79 KB (6,274 words) - 06:31, 12 May 2025
  • Thumbnail for Gestational diabetes
    proposed. c-MET may interact with FoxM1, a molecule important in the cell cycle, as FOXM1 levels decrease when c-MET is not present. Additionally, c-MET may...
    92 KB (11,177 words) - 19:10, 5 May 2025
  • Thumbnail for New York Mets
    The New York Mets are an American professional baseball team based in the New York City borough of Queens. The Mets compete in Major League Baseball (MLB)...
    153 KB (14,308 words) - 01:01, 1 May 2025
  • Thumbnail for Myogenesis
    muscular defects. Associated Genetic Factors: PAX3 and c-Met Mutations in PAX3 can cause a failure in c-Met expression. Such a mutation would result in a lack...
    24 KB (2,799 words) - 10:27, 23 January 2025
  • Thumbnail for MetOp
    of MetOp-A and MetOp-B, all three MetOp spacecraft were operated simultaneously until decommissioning of MetOp-A, MetOp-B and eventually MetOp-C. MetOp...
    25 KB (2,810 words) - 03:38, 26 April 2025
  • Thumbnail for Dihexa
    hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c-Met. The compound has been found to potently improve cognitive function in animal...
    7 KB (492 words) - 16:29, 10 May 2025
  • Thumbnail for Hepatocyte growth factor
    tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by platelets, and mesenchymal...
    23 KB (2,623 words) - 08:53, 15 March 2025
  • Thumbnail for Ministry of Electronics and Information Technology
    Centre for Development of Advanced Computing (C-DAC) Centre for Materials for Electronics Technology (C-MET) National Institute of Electronics and Information...
    12 KB (518 words) - 07:58, 25 April 2025
  • Thumbnail for Motherwell F.C.
    representatives of the two main Motherwell works teams Glencairn FC and Alpha F.C. met in Baillie's pub in the town's Merry Street, and decided to merge the two...
    88 KB (6,450 words) - 23:11, 27 April 2025
  • Thumbnail for How I Met Your Mother
    How I Met Your Mother (often abbreviated as HIMYM) is an American sitcom created by Craig Thomas and Carter Bays for CBS. The series, which aired from...
    153 KB (15,878 words) - 18:32, 11 May 2025
  • The Met Office, until November 2000 officially the Meteorological Office, is the United Kingdom's national weather and climate service. It is an executive...
    36 KB (3,408 words) - 20:47, 18 April 2025
  • Thumbnail for Epithelioid sarcoma
    PMID 22701332. Kuhnen, C.; Tolnay, Edina; Steinau, Hans Ulrich; Voss, Bruno; Müller, Klaus-Michael (1998). "Expression of c-Met receptor and hepatocyte...
    52 KB (5,913 words) - 23:27, 21 February 2025
  • Thumbnail for Cabozantinib
    hepatocellular carcinoma. It is a small-molecule tyrosine-kinase inhibitor (TKI) of c-Met (HGFR) and VEGFR2, and also inhibits AXL, RET, and FLT3. It was discovered...
    24 KB (2,062 words) - 19:34, 28 March 2025
  • Thumbnail for Adam Met
    December 23, 2024. "AJR's Adam Met earns PhD". 105.7 The Point. December 10, 2021. Retrieved December 23, 2024. Jones, C. T. (September 27, 2024). "This...
    18 KB (1,379 words) - 18:22, 6 May 2025
  • Milano-Bicocca). The journal was formed by the merger of Journal of Physics C: Solid State Physics and Journal of Physics F: Metal Physics in 1989. This...
    3 KB (205 words) - 10:25, 4 August 2024
  • Thumbnail for Centre for Development of Advanced Computing
    computing C-DAC branches and training centres include: C-DAC Pune (Headquarters) C-DAC Mumbai C-DAC Bangalore C-DAC Chennai C-DAC Delhi C-DAC Kolkata C-DAC...
    27 KB (2,077 words) - 14:34, 14 April 2025
  • The name of the club was changed to Leeds Met Carnegie during the early part of the 1990s. In 2004, Leeds Met left the Northern Universities League for...
    5 KB (425 words) - 11:29, 16 April 2025
  • Tpr leucine zipper. The Tpr-Met fusion protein lacks the extracellular, transmembrane and juxtamembrane domains of c-Met receptor, and has gained the...
    6 KB (658 words) - 10:12, 27 March 2024
  • Thumbnail for Oleocanthal
    small drug inhibitor of C-Met, as well a potential monoclonal antibody against hereditary gingival fibromatosis (HGF) and C-Met. Hydroxytyrosol Oleuropein...
    12 KB (1,218 words) - 16:36, 26 February 2025
  • Thumbnail for Incyte
    (Baricitinib), and Iclusig (ponatinib). In 2013, Novartis acquired Incyte's c-Met inhibitor capmatinib (INC280, INCB028060), which is marketed under the brand...
    10 KB (713 words) - 04:38, 13 March 2025
  • Thumbnail for C. Sankaran Nair
    gathering force in those days. In 1897, when the First Provincial Conference met in Madras, he was invited to preside over it. The same year, when the Indian...
    14 KB (1,453 words) - 04:04, 11 May 2025
  • Thumbnail for Vebreltinib
    cancer. Vebreltinib selectively binds to c-Met, preventing its phosphorylation and thereby disrupting c-Met signal transduction pathways. In China, it...
    4 KB (165 words) - 11:46, 21 October 2024
  • Thumbnail for Crizotinib
    treatment of non-small cell lung carcinoma (NSCLC). Crizotinib inhibits the c-Met/Hepatocyte growth factor receptor (HGFR) tyrosine kinase, which is involved...
    22 KB (1,866 words) - 05:42, 2 November 2024
  • Thumbnail for Lockheed C-130 Hercules
    an 80 in (2.0 m) plug at the rear of the fuselage. A single C-130K was purchased by the Met Office for use by its Meteorological Research Flight, where...
    110 KB (12,413 words) - 22:53, 4 May 2025
  • owned by DiGiorgio and by C&S Wholesale Grocers) was common in all Met Foods stores along with Met Foods' less common Met Foods' Brand. Today the private...
    3 KB (185 words) - 17:14, 10 February 2025
  • Thumbnail for Savolitinib
    Savolitinib is an experimental small molecule inhibitor of c-Met. It is being investigated for the treatment of cancer by AstraZeneca. It is in phase...
    3 KB (104 words) - 03:01, 23 December 2024
  • Thumbnail for Metropolitan Museum of Art
    The Metropolitan Museum of Art, colloquially referred to as the Met, is an encyclopedic art museum in New York City. By floor area, it is the third-largest...
    184 KB (18,891 words) - 16:53, 11 May 2025
  • Thumbnail for Helixmith
    antibody pipeline including VM507, an antibody that can detect and activate c-MET, receptor of hepatocyte growth factor (HGF). Helixmith is also developing...
    9 KB (1,202 words) - 14:46, 21 March 2025