The complement system, also known as complement cascade, is a part of the humoral, innate immune system and enhances (complements) the ability of antibodies...
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fixed point binary values. As with the ones' complement and sign-magnitude systems, two's complement uses the most significant bit as the sign to indicate...
46 KB (6,069 words) - 12:37, 28 July 2025
specific computer represents numbers. A ones' complement system or ones' complement arithmetic is a system in which negative numbers are represented by...
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include phagocytosis, antimicrobial peptides called defensins, and the complement system. Jawed vertebrates, including humans, have even more sophisticated...
119 KB (13,589 words) - 18:30, 24 July 2025
classical complement pathway is one of three pathways which activate the complement system, which is part of the immune system. The classical complement pathway...
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Humoral immunity (redirect from Humoral immune system)
immunity that is mediated by macromolecules – including secreted antibodies, complement proteins, and certain antimicrobial peptides – located in extracellular...
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pathway is a type of cascade reaction of the complement system and is a component of the innate immune system, a natural defense against infections. The...
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Complement deficiency is an immunodeficiency of absent or suboptimal functioning of one of the complement system proteins. Because of redundancies in the...
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formation of a membrane attack complex (MAC) and target cell lysis. Complement system is efficiently activated by human IgG1, IgG3 and IgM antibodies, weakly...
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Aggregate complementation, the separation of pitch-class collections into complementary sets Complementary color, in the visual arts Complement system (immunology)...
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involved organs/tissues. The complement system is a biochemical cascade of the immune system that helps, or "complements", the ability of antibodies to...
44 KB (4,847 words) - 17:37, 16 July 2025
Complement component 4 (C4), in humans, is a protein involved in the intricate complement system, originating from the human leukocyte antigen (HLA) system...
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the activation of the host's complement system, and as such is an effector of the immune system. Antibody-mediated complement activation leads to MAC deposition...
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characterized. In primates, CR1 serves as the main system for processing and clearance of complement opsonized immune complexes. It has been shown that...
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A complement receptor is a membrane-bound receptor belonging to the complement system, which is part of the innate immune system. Complement receptors...
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Complement control proteins are proteins that interact with components of the complement system. The complement system is tightly regulated by a network...
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C-reactive protein (redirect from Complement reactive protein)
dying cells (and some types of bacteria) in order to activate the complement system via C1q. CRP is synthesized by the liver in response to factors released...
48 KB (5,497 words) - 17:00, 16 July 2025
The complement component 1q (or simply C1q) is a protein complex involved in the complement system, which is part of the innate immune system. C1q together...
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Complement component 3, often simply called C3, is a protein of the immune system that is found primarily in the blood. It plays a central role in the...
15 KB (1,758 words) - 16:58, 16 July 2025
the complement system, acting as a multi-domain serine protease. Deficiency of C2 has been associated with certain autoimmune diseases. The Complement system...
16 KB (2,068 words) - 16:58, 16 July 2025
Anaphylatoxin (category Complement system)
Anaphylatoxins, or complement peptides, are fragments (C3a, C4a and C5a) that are produced as part of the activation of the complement system. Complement components...
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inflammatory function (C3a desarginine). C3a is an effector of the complement system with a range of functions including T cell activation and survival...
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attack, kidney failure, and death. The complement system activation may be due to mutations in the complement regulatory proteins (factor H, factor I...
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10q26 Complement Factor B/Complement Component 2 (CFB/CC2) on chromosome 6 at 6p21.3[citation needed] Polymorphisms in genes for complement system proteins:...
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complement system. It binds to iC3b (inactive derivative of C3b), C3dg, or C3d. B cells express CR2 on their surfaces, allowing the complement system...
14 KB (1,829 words) - 05:28, 19 July 2025
nocturnal hemoglobinuria, proteins known as the "complement system", which is part of the immune system, become overactive because of a genetic mutation...
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Antibody (section Activation of complement)
recognize multiple distinct (unrelated) antigens. These can work with the complement system in the earliest phases of an immune response to help facilitate clearance...
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Immunodeficiency (redirect from Immune-system deficiencies)
where there is no function of the spleen Complement deficiency is where the function of the complement system is deficient In reality, immunodeficiency...
28 KB (2,595 words) - 07:24, 9 June 2025
cleavage of complement component C5 by protease C5-convertase into C5a and C5b fragments. C5b is important in late events of the complement cascade, an...
15 KB (1,654 words) - 17:04, 22 July 2025
Inflammation (section Plasma cascade systems)
vessels moves cells in the blood into the middle of the vessel. The complement system, when activated, creates a cascade of chemical reactions that promotes...
96 KB (9,754 words) - 16:59, 17 July 2025