receptor antagonists (also called beta-blockers or β-blockers) were initially developed in the 1960s, for the treatment of angina pectoris but are now also...

Beta blockers, also spelled β-blockers, are a class of medications that are predominantly used to manage abnormal heart rhythms (arrhythmia), and to protect...

pneumonia (excluding VAP) and community acquired pneumonia in 12 European countries, Canada and Switzerland. Discovery and development of mTOR inhibitors Lemke...

in the elderly, and evidence is increasing that the most frequently used beta blockers at usual doses carry an unacceptable risk of provoking type 2...

specific inhibition of the pacemaker current. It operates by a mechanism different from that of beta blockers and calcium channel blockers, which are two commonly...

Nebivolol is a beta blocker used to treat high blood pressure and heart failure. As with other β-blockers, it is generally a less preferred treatment for...

blood–brain barrier, lipophilic beta blockers such as propranolol and metoprolol are more likely than other less lipophilic beta blockers to cause sleep disturbances...

events during game development and are used to track game's progress. Such milestones may be, for example, first playable, alpha, or beta game versions. Project...

cardioprotective effects without the added adrenergic block side effects seen with non-selective beta-blockers that concomitantly lower blood pressure. Nebivolol...

down the decline of kidney function compared to calcium channel blockers and beta blockers. As such, ACEis should be the drug treatment of choice for patients...

the airways. Prior to their discovery, the non-selective beta-agonist isoprenaline was used. The aim of the drug development through the years has been...

acidic environment and also better inhibition of the proton pump. Therefore, a new class of PPIs, potassium-competitive acid blockers (P-CABs) or acid pump...

beta-blockers Naphthylaminopropane Quirke V (January 2006). "Putting theory into practice: James Black, receptor theory and the development of the beta-blockers...

led to the discovery of the SSRI drugs. The SSRIs are the most significant class of antidepressants marketed in recent years and are one of the major medicinal...

Analogue-based Drug Discovery. John Wiley & Sons. p. 461. ISBN 9783527607495. Kannam JP, Gersh BJ (9 April 2019). Beta blockers in the management of chronic coronary...

Class Ib Class Ic Class II agents are conventional beta blockers. They act by blocking the effects of catecholamines at the β1-adrenergic receptors, thereby...

drugs): ACE inhibitors, angiotensin receptor blockers, beta-blockers, α blockers, calcium channel blockers, thiazide diuretics, loop diuretics, aldosterone...

Angiotensin II receptor antagonist Beta blocker Circulatory system Discovery and development of angiotensin receptor blockers Gradman AH, Schmieder RE, Lins...

calcium channel blockers. The first member was verapamil, a derivative of papaverine that was initially thought to be a beta blocker and used for angina...

possibly because of pre-existing heart failure in those people. As with other beta blockers, it may interact with calcium channel blockers, catecholamine-depleting...

Beta cells (β-cells) are specialized endocrine cells located within the pancreatic islets of Langerhans responsible for the production and release of...

one of the most popular targets in the field of antiretroviral drug development. Discovery and development of NNRTIs began in the late 1980s and in the...

albuterol (USAN) terbutaline zilpaterol (Beta blockers) butoxamine* First generation (non-selective) β-blockers ICI-118,551* Propranolol * denotes selective...

class of beta blockers, used in the treatment of high blood pressure. Penbutolol is able to bind to both beta-1 adrenergic receptors and beta-2 adrenergic...

control. The discovery and development of NK1 receptor antagonists have elicited antiemetic effect in both acute and especially in delayed phases of emesis...

hypertension. It does not cause fatigue as associated with beta-blockers. Due to the adverse drug event of causing hyperkalemia, as seen with most ACE Inhibitors...

reversing transporters in the synapses. Beta blockers, which counter some of the effects of noradrenaline by blocking beta-adrenergic receptors, are sometimes...

CAMs. There are four distinct betas named in order of discovery: SCN1B, SCN2B, SCN3B, SCN4B (table 2). Beta 1 and beta 3 interact with the alpha subunit...

on beta blockers and cimetidine, and the discovery of statins by Akira Endo. Another champion of the approach of developing chemical analogues of known...

the field of therapeutics, his discovery laid the foundation for the development of beta blockers by Sir James Black to treat heart disease and also reduce...