• get broken down. The ESCRT system is made up of five separate cytosolic protein complexes, known as ESCRT-0, ESCRT-I, ESCRT-II, ESCRT-III and Vps4. and each...
    38 KB (4,883 words) - 07:18, 2 June 2025
  • Thumbnail for SNF8
    is a protein that in humans is encoded by the SNF8 gene. It is a part of ESCRT-II complex. GRCh38: Ensembl release 89: ENSG00000159210 – Ensembl, May 2017...
    4 KB (506 words) - 22:57, 26 September 2024
  • Thumbnail for Exosome (vesicle)
    required for transport (ESCRT) dependent pathway. ESCRT machinery mediates the ubiquitinated pathway consisting of protein complexes; ESCRT-0, -I, -II, -III...
    71 KB (7,573 words) - 20:48, 29 May 2025
  • Thumbnail for Vps37b, escrt-i subunit
    VPS37B, ESCRT-I subunit is a protein that in humans is encoded by the VPS37B gene. GRCh38: Ensembl release 89: ENSG00000139722 – Ensembl, May 2017 GRCm38:...
    769 bytes (114 words) - 23:33, 8 November 2024
  • Thumbnail for VPS25
    the endosome-associated complex ESCRT-II (Endosomal Sorting Complexes Required for Transport protein II). ESCRT (ESCRT-I, -II, -III) complexes orchestrate...
    7 KB (816 words) - 02:26, 28 September 2024
  • Thumbnail for TSG101
    tumorigenesis and/or progression. The main role of TSG101 is to participate in ESCRT pathway. This pathway facilitates reverse topology budding and formation...
    16 KB (1,970 words) - 00:17, 14 August 2024
  • Thumbnail for Wesley Sundquist
    membrane remodeling by the Endosomal Sorting Complexes Required for Transport (ESCRT) pathway. Sundquist was born in Saint Paul, Minnesota on September 11, 1959...
    12 KB (1,043 words) - 03:06, 2 June 2025
  • Thumbnail for Henipavirus
    pro-inflammatory response and is also known to promote the viral budding process via a ESCRT-dependent pathway. Cell receptor ephrin-B2, which is located on epithelial...
    22 KB (2,507 words) - 21:44, 7 May 2025
  • Thumbnail for Two-domain system
    required for transport (ESCRT III), involved in eukaryotic cell division, are found in all Thermoproteati groups. The ESCRT-III-like proteins constitute...
    42 KB (4,633 words) - 20:19, 22 May 2025
  • Thumbnail for Mumps virus
    endosomal sorting complex required for transport (ESCRT) structures at the site of budding. There, ESCRT proteins form into concentric spirals and push the...
    22 KB (2,880 words) - 02:29, 15 March 2025
  • Thumbnail for VPS28
    the ESCRT-I complex (endosomal complexes required for transport) involved in the sorting of ubiquitinated protein. The two other subunits of ESCRT-I are...
    7 KB (906 words) - 06:51, 29 December 2023
  • Thumbnail for Nuclear envelope
    process dependent on "endosomal sorting complexes required for transport" (ESCRT) made up of cytosolic protein complexes. During nuclear membrane rupture...
    18 KB (2,035 words) - 14:00, 6 April 2025
  • Thumbnail for Polydactyly
    Anderson, Kathryn V.; Lacy, Elizabeth; Selleri, Licia (October 2014). "ESCRT-II/Vps25 Constrains Digit Number by Endosome-Mediated Selective Modulation...
    63 KB (7,279 words) - 00:43, 25 May 2025
  • Thumbnail for VPS24
    along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional...
    8 KB (1,026 words) - 21:54, 3 March 2023
  • nor the FtsZ mechanism. They use a primitive version of the eukaryotic ESCRT-III system (also known as Cdv) to manipulate the membrane into separating...
    20 KB (2,256 words) - 19:37, 7 March 2025
  • Thumbnail for Archaea
    Cdv fulfills a similar role. This machinery is related to the eukaryotic ESCRT-III machinery which, while best known for its role in cell sorting, also...
    155 KB (16,853 words) - 06:19, 1 June 2025
  • Thumbnail for VPS4A
    "Interaction of the mammalian endosomal sorting complex required for transport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1"....
    9 KB (1,107 words) - 16:37, 28 October 2022
  • furrow ingression. In addition, centralspindlin's interaction with the ESCRT III[broken anchor] allows for abscission to occur. Centralspindlin is a...
    6 KB (587 words) - 15:53, 11 April 2025
  • Thumbnail for CHMP6
    proteins and a part of endosomal sorting complexes required for transport-III (ESCRT-III) complex. Multivesicular body GRCh38: Ensembl release 89: ENSG00000176108...
    5 KB (640 words) - 21:34, 11 August 2024
  • Thumbnail for Archaeal virus
    complex required for transport (ESCRT) is used by some archaeal viruses, such as STIV and SIRV2, for assembly and exit. ESCRT is used by some eukaryotic viruses...
    51 KB (6,431 words) - 13:36, 28 May 2025
  • Thumbnail for CHMP2B
    one of the endosomal sorting complexes required for transport (ESCRT) - specifically ESCRT-III - which are a series of complexes involved in cell membrane...
    8 KB (1,047 words) - 05:28, 24 December 2023
  • Thumbnail for Cytoskeleton
    tubulin-like (often FtsZ-ring) proteins and sometimes (Thermoproteota) ESCRT-III, which in eukaryotes still has a role in the last step of division....
    45 KB (5,117 words) - 13:25, 26 May 2025
  • Thumbnail for Galectin
    cellular response to membrane damage are expanding, e.g. Galectin-3 recruits ESCRTs to damaged lysosomes so that lysosomes can be repaired. This occurs before...
    34 KB (3,864 words) - 01:49, 22 June 2024
  • Thumbnail for Viral entry
    Pisano, Gina; Veettil, Mohanan Valiya; Chandran, Bala (October 2016). "ESCRT-I Protein Tsg101 Plays a Role in the Post-macropinocytic Trafficking and...
    15 KB (1,843 words) - 01:53, 27 May 2025
  • Thumbnail for VPS4B
    "Ultrastructural analysis of ESCRT proteins suggests a role for endosome-associated tubular-vesicular membranes in ESCRT function". Traffic. 7 (11): 1551–66...
    8 KB (1,036 words) - 21:02, 8 January 2024
  • Thumbnail for AAA proteins
    involves the sequential action of three multiprotein complexes, ESCRT I to III (ESCRT standing for 'endosomal sorting complexes required for transport')...
    14 KB (1,588 words) - 07:52, 28 March 2025
  • Thumbnail for ATG9A
    Enzymatically, it is a lipid scramblase. ATG9A interacts with IQGAP1 and the ESCRT machinery in membrane remodeling. GRCh38: Ensembl release 89: ENSG00000198925...
    5 KB (569 words) - 20:56, 3 March 2023
  • Thumbnail for Hepatitis C virus
    reticulum through the endosomal sorting complex required for transport (ESCRT) pathway. This pathway is normally utilized to bud vesicles out of the cell...
    54 KB (6,645 words) - 21:03, 29 May 2025
  • Thumbnail for CHMP4C
    MIT domain-containing proteins bind to multiple components of the human ESCRT III complex". Genomics. 88 (3): 333–46. doi:10.1016/j.ygeno.2006.04.003...
    4 KB (513 words) - 22:43, 18 August 2023
  • Thumbnail for Endosome
    addition of ubiquitin. The endosomal sorting complexes required for transport (ESCRTs) recognise this ubiquitin and sort the protein into the forming lumenal...
    22 KB (2,647 words) - 11:03, 19 May 2025