• Human germline engineering (HGE) is the process by which the genome of an individual is modified in such a way that the change is heritable. This is achieved...
    43 KB (6,483 words) - 22:07, 25 June 2025
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    Designer baby (category Genetic engineering)
    criticism and legal debates. This highlights the implications of germline engineering, which involves introducing the desired genetic material into the...
    78 KB (8,908 words) - 07:56, 18 June 2025
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    original on 5 August 2001. Smith KR, Chan S, Harris J (October 2012). "Human germline genetic modification: scientific and bioethical perspectives". Archives...
    135 KB (14,251 words) - 06:15, 28 June 2025
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    not prohibit germline engineering. A 2020 issue of the journal Bioethics was devoted to moral issues surrounding germline genetic engineering in people....
    185 KB (18,706 words) - 03:27, 28 June 2025
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    CRISPR (category Biological engineering)
    Genome-wide CRISPR-Cas9 knockout screens Glossary of genetics Human germline engineering Human Nature (2019 documentary film) MAGESTIC New eugenics Prime...
    115 KB (11,900 words) - 21:51, 4 June 2025
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    CRISPR gene editing (category Genetic engineering)
    arising from somatic mutations such as cancer. However, its use in human germline genetic modification is highly controversial. The development of this...
    177 KB (20,566 words) - 06:05, 28 June 2025
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    Human genetic enhancement or human genetic engineering refers to human enhancement by means of a genetic modification. This could be done in order to cure...
    93 KB (10,228 words) - 20:00, 16 May 2025
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    Arnadottir GA, Eiriksson O, et al. (January 2021). "Differences between germline genomes of monozygotic twins". Nature Genetics. 53 (1): 27–34. doi:10...
    266 KB (25,702 words) - 23:15, 13 June 2025
  • Thumbnail for Germline mutation
    A germline mutation, or germinal mutation, is any detectable variation within germ cells (cells that, when fully developed, become sperm and ova). Mutations...
    25 KB (3,085 words) - 03:46, 17 September 2024
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    1007/s11105-021-01286-7. S2CID 233713026. "Special Issue on Human Germline Editing". Bioethics. 34. 2020. "Customized Human Genes: New Promises and Perils". Scientific...
    79 KB (9,365 words) - 19:52, 22 May 2025
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    tested and trialed. A few of these emerging technologies include: human genetic engineering (gene therapy), neurotechnology (neural implants and brain–computer...
    31 KB (3,072 words) - 22:08, 24 May 2025
  • Thumbnail for Gregory Stock
    (1991) Metaman: The Merging of Humans and Machines into a Global Superorganism (1993) Engineering the Human Germline: An Exploration of the Science and...
    6 KB (505 words) - 16:47, 10 May 2025
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    2014. Kleiderman, Erika; Stedman, Ian Norris Kellner (April 2020). "Human germline genome editing is illegal in Canada, but could it be desirable for some...
    85 KB (5,706 words) - 21:39, 24 May 2025
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    the human genome – so-called germline gene editing." In 2017, the National Academies of Sciences, Engineering, and Medicine published a report "Human Genome...
    120 KB (12,426 words) - 00:07, 20 June 2025
  • advance a comprehensive, scientifically based position against human germline engineering. It was also the first to compile documented cases of genetic...
    9 KB (778 words) - 18:34, 21 March 2025
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    rate of both somatic and germline mutations per cell division than humans. The disparity in mutation rate between the germline and somatic tissues likely...
    119 KB (14,264 words) - 07:00, 9 June 2025
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    according to Kirkwood. Individual organisms ordinarily age and die, while the germlines which connect successive generations are potentially immortal. The basis...
    88 KB (10,517 words) - 20:14, 26 June 2025
  • Thumbnail for Convention for the Protection of Human Rights and Dignity of the Human Being with regard to the Application of Biology and Medicine
    The Convention for the Protection of Human Rights and Dignity of the Human Being with regard to the Application of Biology and Medicine, otherwise known...
    20 KB (1,868 words) - 11:19, 16 December 2024
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    that in somatic cells from the same individual. This low frequency in the germline leads to embryos that have a low frequency of point mutations in the next...
    48 KB (5,427 words) - 05:01, 2 June 2025
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    different discoveries and advancements led to the development of genetic engineering. Human-directed genetic manipulation began with the domestication of plants...
    55 KB (6,765 words) - 11:43, 11 December 2024
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    Our Posthuman Future (category Books about human rights)
    in human genetics providing the argument against unregulated modification of human germline cells. Fukuyama argues that the moral status of human embryos...
    14 KB (1,495 words) - 20:47, 4 June 2025
  • In contrast, gametes derive from meiosis within the germ cells of the germline and they fuse during sexual reproduction. Stem cells also can divide through...
    15 KB (1,793 words) - 12:56, 25 May 2025
  • Thumbnail for United Nations Declaration on Human Cloning
    The United Nations Declaration on Human Cloning was a nonbinding statement against all forms of human cloning approved by a divided UN General Assembly...
    3 KB (353 words) - 11:19, 16 December 2024
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    is the elevation of well-being in humans and other animals through biological methods, including germline engineering through screening embryos with genes...
    6 KB (644 words) - 00:33, 15 May 2025
  • does represent a form of cloning, but this is not ethically equivalent to germline genome editing, and references to Brave New World may lead some readers...
    80 KB (10,034 words) - 21:52, 26 June 2025
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    Korean biologist, Hwang Woo-suk, who claimed to have created the first human embryonic stem cells by cloning in 2004. Hwang and his research team at...
    29 KB (3,266 words) - 11:35, 24 June 2025
  • scientific research related to germline intervention and its implications to law and bioethics. Gene patents [3] Patents for human genetic material grant exclusivity...
    7 KB (827 words) - 03:40, 4 January 2025
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    development and use of human embryos. Most commonly, this controversy focuses on embryonic stem cells. Not all stem cell research involves human embryos. For example...
    59 KB (7,159 words) - 03:29, 11 June 2025
  • delivery. They can become endogenous, integrating their genome into the host germline genome, so that the virus is henceforth inherited by the host's descendants...
    17 KB (1,876 words) - 02:30, 1 April 2025
  • Thumbnail for Leon Kass
    proponent of liberal arts education via the "Great Books," as a critic of human cloning, life extension, euthanasia and embryo research, and for his tenure...
    45 KB (5,846 words) - 03:04, 11 June 2025