In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose. The etymology stems from...

In biochemistry and pharmacology, receptors are chemical structures, composed of protein, that receive and transduce signals that may be integrated into...

In biochemistry and pharmacology, the Hill equation refers to two closely related equations that reflect the binding of ligands to macromolecules, as a...

rely on the concept of protein-ligand complex interaction. Dissociation constant Ligand (biochemistry) Receptor (biochemistry) Bohl CE, Gao W, Miller DD,...

A ligand binding assay (LBA) is an assay, or an analytic procedure, which relies on the binding of ligand molecules to receptors, antibodies or other...

more central atoms or ions Ligand (biochemistry), a substance that binds to a protein a 'guest' in host–guest chemistry Ligand-gated ion channel This disambiguation...

drug; the concentration of competing ligand in a competition assay which would occupy 50% of the receptors if no ligand were present. The Cheng-Prusoff equation...

for measuring dose-response relationships are organ bath preparations, ligand binding assays, functional assays, and clinical drug trials. Specific to...

Smart ligands are affinity ligands selected with pre-defined equilibrium ( K d {\displaystyle K_{d}} ), kinetic ( k o f f {\displaystyle k_{off}} , k o...

or LC-MS/MS) relevant to clinical and forensic toxicology". Clinical Biochemistry. 38 (4). Elsevier BV: 310–318. doi:10.1016/j.clinbiochem.2005.01.014...

v t e Pharmacology Ligand (biochemistry) Drug Neurotransmitter Agonist-antagonist Pharmacophore Pharmacodynamics Pharmacokinetics Compartment Bioequivalence...

systems. Ligand conduction: a general catalytic principle in chemical, osmotic and chemiosmotic reaction systems". European Journal of Biochemistry. 95 (1):...

displacement by one ligand of another ligand in a complex with the substrate. Binding selectivity is of major importance in biochemistry and in chemical separation...

morphogenetic front of SHH ligand moves and begins to grow more concentrated, cells that are exposed to higher levels of the ligand respond by switching off...

Ligand-gated ion channels (LICs, LGIC), also commonly referred to as ionotropic receptors, are a group of transmembrane ion-channel proteins which open...

(also known as ephrin ligands or Eph family receptor interacting proteins) are a family of proteins that serve as the ligands of the Eph receptor. Eph...

the intended article. Dissociation curve may refer to: Ligand (biochemistry)#Receptor/ligand binding affinity represented in a graph Oxygen-haemoglobin...

The binding partner of the macromolecule is often referred to as a ligand. Ligands may include other proteins (resulting in a protein–protein interaction)...

v t e Pharmacology Ligand (biochemistry) Drug Neurotransmitter Agonist-antagonist Pharmacophore Pharmacodynamics Pharmacokinetics Compartment Bioequivalence...

trapping, also known as ligand trapping or ligand entrapment, pertains to an inhibition mechanism in which a small molecule ligand becomes enclosed and locked...

In chemistry, biochemistry, and pharmacology, a dissociation constant (KD) is a specific type of equilibrium constant that measures the propensity of a...

have a high binding affinity when their ligand is present in high concentrations, but must also release the ligand when it is present at low concentrations...

are several ways molecules (in this case, also known as ligands) can interact with DNA. Ligands may interact with DNA by covalently binding, electrostatically...

In biochemistry, an orphan receptor is a protein that has a similar structure to other identified receptors but whose endogenous ligand has not yet been...

(1999) “Hydrogen Bonding Modulates Proximal Ligand Binding in Sperm Whale Myoglobin Mutants” Biochemistry 38:11086-92. Decatur, S.M., Franzen, S., DePillis...

In biochemistry, allosteric regulation (or allosteric control) is the regulation of an enzyme by binding an effector molecule at a site other than the...

protein kinase C beta II complexed with a bisindolylmaleimide inhibitor". Biochemistry. 45 (47): 13970–81. doi:10.1021/bi061128h. PMID 17115692. Page CS, Bates...

-methylphenyl)-5-isoxazolyl]-1-propylpyridine is a potent and selective ligand for the sigma-1 receptor, with a reported binding affinity of Ki = 0.08...

v t e Pharmacology Ligand (biochemistry) Drug Neurotransmitter Agonist-antagonist Pharmacophore Pharmacodynamics Pharmacokinetics Compartment Bioequivalence...

In biochemistry, receptor–ligand kinetics is a branch of chemical kinetics in which the kinetic species are defined by different non-covalent bindings...