The p75 neurotrophin receptor (p75NTR) was first identified in 1973 as the low-affinity nerve growth factor receptor (LNGFR) before discovery that p75NTR...
37 KB (4,235 words) - 04:17, 19 March 2025
Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide primarily involved in the regulation of growth, maintenance, proliferation, and survival...
27 KB (3,110 words) - 06:33, 25 May 2025
neurotrophic factor receptors are the p75 and the "Trk" families of tyrosine kinase receptors. p75 is a low affinity neurotrophin receptor, to which all...
5 KB (670 words) - 10:25, 10 April 2025
responding to this growth factor, TrkB (pronounced "Track B") and the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). It may...
50 KB (5,881 words) - 13:31, 5 May 2025
Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. Human EGF is 6-kDa and has...
17 KB (1,716 words) - 11:48, 25 May 2025
Cenegermin (redirect from Recombinant human nerve growth factor)
agonist of the tropomyosin receptor kinase A (TrkA) and low-affinity nerve growth factor receptor (p75NTR). The most common side effects include eye pain...
7 KB (389 words) - 08:54, 17 February 2025
Tropomyosin receptor kinase A (TrkA), also known as high affinity nerve growth factor receptor, neurotrophic tyrosine kinase receptor type 1, or TRK1-transforming...
28 KB (3,328 words) - 15:54, 29 October 2024
High affinity neurotrophin receptors Ephrin receptors Integrins Low Affinity Nerve Growth Factor Receptor NMDA receptor Several Immune receptors Toll-like...
22 KB (2,480 words) - 14:02, 24 March 2025
is one other NT-3 receptor family besides the Trks (TrkC & TrkB), called the "LNGFR" (for "low affinity nerve growth factor receptor"). As opposed to TrkC...
30 KB (3,901 words) - 00:12, 24 May 2025
Hepatocyte growth factor receptor (HGF receptor) is a protein that in humans is encoded by the MET gene. The protein possesses tyrosine kinase activity...
59 KB (6,731 words) - 05:32, 23 May 2025
receptor for BDNF, and showed that they were sufficient to mediate signaling without the requirement of the Low affinity Nerve Growth Factor receptor...
26 KB (2,634 words) - 13:07, 26 May 2025
Neurotrophin-3 (redirect from Neurotrophic Factor-3)
binds a second-receptor type besides Trk receptors, called the LNGFR (for "low affinity nerve growth factor receptor). TrkC is a receptor tyrosine kinase...
14 KB (1,820 words) - 07:02, 1 January 2025
Tropomyosin receptor kinase B (TrkB), also known as tyrosine receptor kinase B, or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor, type...
39 KB (4,393 words) - 05:21, 26 March 2025
Neurotrophin (redirect from Neuronal growth associated protein)
of receptors for neurotrophins: p75 and the "Trk" family of Tyrosine kinases receptors. Nerve growth factor (NGF), the prototypical growth factor, is...
28 KB (3,081 words) - 12:49, 24 May 2025
This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. FGFR2 has important...
14 KB (1,745 words) - 09:02, 15 July 2024
Vascular endothelial growth factor (VEGF, /vɛdʒˈɛf/), originally known as vascular permeability factor (VPF), is a signal protein produced by many cells...
40 KB (4,578 words) - 12:30, 10 September 2024
Placental growth factor (PlGF) is a protein that in humans is encoded by the PGF gene. Placental growth factor is a member of the VEGF (vascular endothelial...
15 KB (1,867 words) - 09:38, 20 April 2025
OECs have been identified with high or low cell surface expression of low-affinity nerve growth factor receptor (p75). Neuroscience Neuroglia Olfaction...
18 KB (2,263 words) - 21:54, 8 March 2025
sufficient to mediate signaling without the requirement of the Low affinity Nerve Growth Factor receptor (LNGFR). Glass identified the E3 ubiquitin ligases, MuRF1...
11 KB (1,056 words) - 22:59, 24 May 2025
Fibroblast growth factor receptor 3 (FGFR-3) is a protein that in humans is encoded by the FGFR3 gene. FGFR3 has also been designated as CD333 (cluster...
17 KB (1,844 words) - 17:02, 8 May 2025
inhibitory factor receptor Leukocyte extravasation Leukocyte-promoting factor Linear epitope Lipid A Lipopolysaccharide binding protein Low-affinity nerve growth...
13 KB (1,237 words) - 01:24, 15 January 2024
GRB2 (redirect from Growth factor receptor-bound protein 2)
Growth factor receptor-bound protein 2, also known as Grb2, is an adaptor protein involved in signal transduction/cell communication. In humans, the GRB2...
82 KB (9,365 words) - 09:44, 2 March 2025
Somatostatin (redirect from Growth Hormone Inhibatory Hormone)
Pasireotide is somatostatin analog with a 40-fold increased affinity to somatostatin receptor 5 compared to other somatostatin analogs. Six somatostatin...
23 KB (2,531 words) - 13:11, 14 April 2025
has been shown to interact with: E2F1, HNRNPU, IL1A, Low affinity nerve growth factor receptor, NUCB2, and P53 ENSG00000288364 GRCh38: Ensembl release...
11 KB (1,275 words) - 09:54, 13 March 2025
The μ-opioid receptors (MOR) are a class of opioid receptors with a high affinity for enkephalins and beta-endorphin, but a low affinity for dynorphins...
49 KB (4,886 words) - 04:07, 28 April 2025
Pleiotrophin (redirect from Heparin affinity regulatory peptide)
heparin-binding growth factor 8 (HBGF-8) or neurite growth-promoting factor 1 (NEGF1) or heparin affinity regulatory peptide (HARP) or heparin binding growth associated...
14 KB (1,649 words) - 07:53, 21 December 2023
into co-receptors for p75, such as the sortilin co-receptor, has implicated sortilin in connection to neurotrophins, a type of nerve growth factor. The p75...
21 KB (3,129 words) - 01:57, 6 February 2025
function in keratinocytes. They are also expressed on peripheral nerve terminals. These receptors play a role in antinociception, or the relief of pain. In the...
32 KB (3,086 words) - 18:05, 24 February 2025
successful NMDA receptor antagonists for neurodegenerative diseases continued and focused on developing low affinity blockers. However the affinity could not...
109 KB (12,198 words) - 23:08, 22 May 2025
Prolactin (redirect from Receptors, prolactin)
cycle-related functions as a growth-, differentiating- and anti-apoptotic factor. As a growth factor, binding to cytokine-like receptors, it influences hematopoiesis...
58 KB (6,049 words) - 23:34, 22 May 2025