A molecular glue is a type of small molecule that modulates protein–protein interactions in cells by enhancing the affinity between proteins. These compounds...

(kolla), meaning 'glue'. These proteins form a molecular bond with the glued object.[citation needed] Conventionally, keratin glues, while made from animal...

Adhesive, also known as glue, cement, mucilage, or paste, is any non-metallic substance applied to one or both surfaces of two separate items that binds...

announced a $1.64bn partnership with Neomorph aimed at developing new molecular glue degraders for multiple targets across oncology and immunology. In the...

AION Labs unveiled TenAces Biosciences, a venture in the field of molecular glue discovery using machine learning. Formed from AION Labs' initiative...

able to execute their functions normally. In addition to serving as "molecular glue", CAMs play important roles in the cellular mechanisms of growth, contact...

known as wood glue (a term that may also refer to other types of glues), PVA glue, white glue, carpenter's glue, school glue, or Elmer's Glue in the US,...

Molecular glues often have been discovered through serendipity, though various methodologies have been explored to expedite the discovery of molecular glues. Biologic...

When TIR1/ AFB proteins bind to auxin, the auxin molecule acts as a 'molecular glue', a term coined by Ning Zheng, that allows these proteins to then bind...

protein biochemist known for his pioneering work in the fields of molecular glues and targeted protein degradation. He is currently a professor in the...

Hot-melt adhesive (HMA), also known as hot glue, is a form of thermoplastic adhesive that is commonly sold as solid cylindrical sticks of various diameters...

the G12D mutation in KRAS dependent cancers. RMC-9805 functions as molecular glue that forms a non-covalent ligand-mediated protein-protein interaction...

increasing their stability and long-term reliability with a form of "molecular glue".[importance?] 21 May – The first industrial commercial production line...

reliability of perovskite solar cells was improved with a new kind of "molecular glue". As of 2021, the existing stability tests for solar panels and solar...

Coagulation reinforces the platelet plug with fibrin threads that act as a "molecular glue". Platelets are a large factor in the hemostatic process. They allow...

applications such as with PROTACs. Derivatized VHL ligands that act as molecular glue degraders have also been discovered through high-throughput screening...

an experimental cereblon E3 ligase modulator, or thalidomide analog (molecular glue) that was discovered and studied by Celgene to see if it was effective...

Casein glue is also used in transformer manufacturing (specifically transformer board) due to its oil permeability. Elmer's Glue-All, Elmer's School Glue and...

interest. Notable recent discoveries include an inhibitor of mTORC1, a molecular glue between UBR7 and p53 that activates p53 tumor suppressor activity, a...

Molecular gastronomy is the scientific approach of cuisine from primarily the perspective of chemistry. The composition (molecular structure), properties...

advances include the discovery that small molecules can function as “molecular glues” that promote protein–protein interactions, the co-discovery of mTOR...

weak acids. The name collagen comes from the Greek κόλλα (kólla), meaning "glue", and suffix -γέν, -gen, denoting "producing". As of 2011, 28 types of human...

required for the production of extracellular virus. Tecovirimat acts as a molecular glue that promotes the dimerization of VP37. The drug prevents the virus...

small‑molecule and protein therapeutic discovery, chemoproteomics, molecular glues, covalent drug design, high‑throughput screening, protein and antibody...

damage. When DNA damage occurs, SUMO protein has been shown to act as a molecular glue to facilitate the assembly of large protein complexes in repair foci...

increasing their stability and long-term reliability with a form of "molecular glue".[importance?] 21 May – The first industrial commercial production line...

RL, Ronau JA, et al. (February 2023). "CRISPR Screen Reveals BRD2/4 Molecular Glue-like Degrader via Recruitment of DCAF16". ACS Chemical Biology. 18 (2):...

'jugular,' Biden briefed". Reuters. 8 May 2021. Retrieved 13 June 2021. ""Molecular glue" strengthens the weak point in perovskite solar cells". New Atlas. 10...

act as adhesives. The term is sometimes used more loosely to describe a glue formed synthetically from biological monomers such as sugars, or to mean...

laboratory advanced the understanding of how the molecular glue thalidomide and its analogues function at the molecular level. To date, thalidomide derivatives...