• Thumbnail for Norepinephrine transporter
    The norepinephrine transporter (NET), also known as noradrenaline transporter (NAT), is a protein that in humans is encoded by the solute carrier family...
    33 KB (3,478 words) - 15:43, 11 January 2025
  • Thumbnail for Norepinephrine–dopamine reuptake inhibitor
    competitively and/or noncompetitively inhibiting the norepinephrine transporter (NET) and dopamine transporter (DAT). NDRIs are used clinically in the treatment...
    5 KB (463 words) - 05:51, 28 January 2025
  • Thumbnail for Monoamine transporter
    three major classes are serotonin transporters (SERTs), dopamine transporters (DATs), and norepinephrine transporters (NETs) and are responsible for the...
    21 KB (2,342 words) - 15:34, 14 September 2024
  • Thumbnail for Norepinephrine
    Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and...
    60 KB (6,685 words) - 20:12, 20 May 2025
  • depression and attention deficit hyperactivity disorder (ADHD). The norepinephrine transporter (NET) serves as the fundamental mechanism for the inactivation...
    34 KB (3,816 words) - 22:08, 29 May 2025
  • Thumbnail for Norepinephrine reuptake inhibitor
    neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline) by blocking the action of the norepinephrine transporter (NET). This in turn...
    7 KB (678 words) - 15:01, 12 December 2024
  • Thumbnail for Dopamine transporter
    cortex, where evidence points to a possibly larger role of the norepinephrine transporter. DAT is implicated in a number of dopamine-related disorders,...
    84 KB (9,201 words) - 10:39, 12 December 2024
  • Thumbnail for Serotonin–norepinephrine reuptake inhibitor
    inhibitors (SSRIs) and norepinephrine reuptake inhibitors (NRIs), which act upon single neurotransmitters. The human serotonin transporter (SERT) and noradrenaline...
    84 KB (8,211 words) - 18:10, 23 May 2025
  • very selective for the dopamine transporter, with little to no effect on the norepinephrine and serotonin transporters 4-Hydroxy-1-methyl-4-(4-methylphenyl)-3-piperidyl...
    19 KB (1,930 words) - 22:33, 23 May 2025
  • simultaneous inhibition of the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT), respectively, increasing their...
    141 KB (16,545 words) - 22:09, 29 May 2025
  • Thumbnail for Norepinephrine releasing agent
    A norepinephrine releasing agent (NRA), also known as an adrenergic releasing agent, is a catecholaminergic type of drug that induces the release of norepinephrine...
    18 KB (1,747 words) - 15:13, 13 February 2025
  • Thumbnail for Monoamine reuptake inhibitor
    (MATs), which include the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT). This in turn results in an increase...
    20 KB (1,388 words) - 21:36, 30 January 2025
  • epinephrine and norepinephrine; subtypes include α1, α2, β1, β2, and β3 receptors Adrenergic transporter (norepinephrine transporter), a protein transporting...
    3 KB (286 words) - 18:10, 25 July 2024
  • Thumbnail for Serotonin–dopamine reuptake inhibitor
    exceptionally difficult to tease apart affinity for the DAT from the norepinephrine transporter (NET) and inhibit the reuptake of dopamine alone. As a result...
    16 KB (1,791 words) - 22:09, 29 May 2025
  • Thumbnail for Vesicular monoamine transporter 2
    proteins for monoamines (i.e., the dopamine transporter, norepinephrine transporter, and serotonin transporter) in monoamine neurons. Other VMAT2 inhibitors...
    29 KB (3,347 words) - 14:46, 25 May 2025
  • Thumbnail for Postural orthostatic tachycardia syndrome
    autonomic cardiac neuropathy, although reduced expression of the norepinephrine transporter may also result in impaired MIBG reuptake and has been implicated...
    99 KB (9,953 words) - 06:57, 28 May 2025
  • Thumbnail for Sertraline
    and pinoxepin. Further work on these compounds led to tametraline, a norepinephrine and weaker dopamine reuptake inhibitor. Development of tametraline was...
    104 KB (10,694 words) - 22:09, 29 May 2025
  • Thumbnail for Reuptake
    Reuptake (category Neurotransmitter transporters)
    of the transporters associated with important neurotransmitters within the body were also very similar in sequence to the GABA and norepinephrine transporters...
    15 KB (1,897 words) - 08:15, 17 July 2024
  • significant association. Attempts to find a correlation between norepinephrine transporter polymorphisms and depression have yielded negative results. One...
    128 KB (15,013 words) - 18:55, 22 May 2025
  • Thumbnail for 2,3-Methylenedioxymethamphetamine
    monoamine transporter (MAT) substrate and inhibitor similarly to 3,4-MDMA. However, while showing similar potency at the norepinephrine transporter (NET)...
    3 KB (173 words) - 13:40, 11 April 2025
  • Thumbnail for Atomoxetine
    Atomoxetine (category Serotonin–norepinephrine reuptake inhibitors)
    Atomoxetine, formerly sold under the brand name Strattera, is a selective norepinephrine reuptake inhibitor (sNRI) medication used to treat attention deficit...
    72 KB (6,250 words) - 20:03, 29 May 2025
  • Thumbnail for Methylphenidate
    Methylphenidate (category Norepinephrine–dopamine reuptake inhibitors)
    monoamine transporters when they are co-administered.[better source needed] Methylphenidate has both dopamine transporter and norepinephrine transporter binding...
    155 KB (14,239 words) - 21:30, 29 May 2025
  • Thumbnail for PCP site 2
    the monoamine transporters (SERTTooltip serotonin transporter, DATTooltip dopamine transporter, NETTooltip norepinephrine transporter). It is associated...
    6 KB (378 words) - 11:29, 28 January 2024
  • Thumbnail for Amitriptyline
    inhibits serotonin transporter (SERT) and norepinephrine transporter (NET). It is metabolized to nortriptyline, a stronger norepinephrine reuptake inhibitor...
    93 KB (8,717 words) - 12:18, 23 May 2025
  • Thumbnail for Serotonin transporter
    The serotonin transporter (SERT or 5-HTT) also known as the sodium-dependent serotonin transporter and solute carrier family 6 member 4 is a protein that...
    31 KB (3,442 words) - 04:14, 20 May 2025
  • Thumbnail for Ampreloxetine
    Ampreloxetine (category Norepinephrine reuptake inhibitors)
    (NOH). It shows high affinity for both the norepinephrine transporter (NET) and the serotonin transporter (SERT), with 4-fold selectivity for the NET...
    5 KB (335 words) - 13:52, 4 December 2024
  • Thumbnail for Trazodone
    trazodone are in the 25–100 mg range. The occupancy of the serotonin transporter (SERT) by trazodone is estimated to be 86% at 100 mg/day and 90% at 150 mg/day...
    120 KB (11,110 words) - 22:25, 29 May 2025
  • Thumbnail for Modafinil
    research, modafinil has little to no affinity for serotonin or norepinephrine transporters and does not directly interact with these systems. However, studies...
    179 KB (16,512 words) - 21:33, 29 May 2025
  • Thumbnail for Phencyclidine
    the opioid receptors, the σ1 receptor, and the dopamine and norepinephrine transporters. These results suggest that PCP is a highly selective ligand...
    57 KB (5,444 words) - 02:58, 17 May 2025
  • Thumbnail for Fluvoxamine
    affinity for the serotonin transporter over the norepinephrine transporter. It has negligible affinity for the dopamine transporter or any other site, with...
    68 KB (6,040 words) - 20:53, 29 May 2025