• Thumbnail for SDHB
    subunit, mitochondrial (SDHB) also known as iron-sulfur subunit of complex II (Ip) is a protein that in humans is encoded by the SDHB gene. The succinate...
    26 KB (3,010 words) - 19:28, 22 May 2025
  • Thumbnail for Succinate dehydrogenase
    The first two subunits, a flavoprotein (SDHA) and an iron-sulfur protein (SDHB), form a hydrophilic head where enzymatic activity of the complex takes place...
    28 KB (2,997 words) - 16:17, 14 May 2025
  • Thumbnail for Agriculture in California
    event ΔL497 (also known as MDR1h and found only in Botrytis group S); and sdhB alleles H272R, H272Y, N230I, and P225F (the only one conferring resistance...
    338 KB (33,777 words) - 23:48, 25 May 2025
  • Thumbnail for Pheochromocytoma
    diagnostic workup. Loss of SDHB staining is indicative of SDHx-related pathogenesis and is particularly noted in tumors with SDHB pathogenic variants. Inhibin...
    165 KB (17,973 words) - 21:53, 29 May 2025
  • Thumbnail for SDHD
    other transmembrane subunit is SDHC. The SDHC/SDHD dimer is connected to the SDHB electron transport subunit which, in turn, is connected to the SDHA subunit...
    21 KB (2,718 words) - 06:22, 3 June 2024
  • Thumbnail for Succinate dehydrogenase complex subunit C
    other transmembrane subunit is SDHD. The SDHC/SDHD dimer is connected to the SDHB electron transport subunit which, in turn, is connected to the SDHA subunit...
    17 KB (2,178 words) - 06:41, 3 June 2024
  • Thumbnail for Paraganglioma
    SDHC (previously PGL3) and SDHB have been identified as causing familial head and neck paragangliomas. Mutations of SDHB play an important role in familial...
    17 KB (1,800 words) - 05:36, 23 May 2025
  • Thumbnail for Mitochondrial complex II deficiency
    SDH plays a key role in metabolism; the catalytic end, made up of SDHA and SDHB oxidizes succinate to fumarate in the tricarboxylic acid (TCA) cycle. The...
    8 KB (866 words) - 15:34, 27 October 2024
  • Thumbnail for Carney triad
    gene pathway involving the succinate dehydrogenase subunits SDHD, SDHC and SDHB. OMIM - Online Mendelian Inheritance in Man. Carney Triad (OMIM 604287) [1]...
    4 KB (520 words) - 03:58, 10 March 2025
  • Thumbnail for Ganglioneuroma
    somatic mosaic origin, such as RET proto-oncogene, CDKN1B, Neurofibromin, SDHB, SDHC, SDHD, VHL, and EPAS1, in association with Pacak-Zhuang syndrome. Pathologically...
    8 KB (741 words) - 20:25, 11 May 2025
  • Thumbnail for Hereditary cancer syndrome
    (succinate:ubiquinone oxidoreductase) subunit genes (SDHD, SDHAF2, SDHC, SDHB). PGL-1 is associated with SDHD mutation, and most PGL-1 individuals with...
    52 KB (5,673 words) - 19:03, 5 April 2025
  • Thumbnail for SDHAF1
    and promotes the maturation of the SDHB subunit of the SDH catalytic dimer. The iron-sulfur (Fe-S) protein subunit SDHB is required for functional succinate...
    8 KB (941 words) - 22:23, 11 April 2024
  • Thumbnail for Oncometabolism
    patients for SDH mutation testing in early stages of cancer. The absence of SDHB in IHC staining would be linked to the presence of SDH oncogene mutations...
    32 KB (3,430 words) - 18:38, 5 April 2025
  • succinate dehydrogenase [ubiquinone] iron–sulfur subunit mitochondrial (SDHB); succinate dehydrogenase complex subunit C (SDHC); and succinate dehydrogenase...
    34 KB (4,073 words) - 21:56, 25 May 2025
  • Thumbnail for Mitochondrial myopathy
    reductase deficiency; succinate dehydrogenase deficiency) SDHA, SDHAF1, SDHD, SDHB AR PS252011 cytochrome b of complex III (MTCYB); Exercise intolerance; multisystem...
    44 KB (3,591 words) - 18:21, 23 May 2025
  • Redevelopment. In 2019 the SDHB released the official design plans for the redevelopment of Dunedin Hospital. On 17 May 2019, the SDHB announced that WSP Opus...
    12 KB (1,328 words) - 22:22, 21 February 2025
  • Thumbnail for Chromosome 1
    encoding protein Sterile alpha motif domain containing 11 SDC3: Syndecan-3 SDHB (1p36) SFPQ (1p34): encoding protein Splicing factor proline and glutamine...
    47 KB (3,307 words) - 00:15, 1 June 2025
  • Thumbnail for Dave Cull
    shock entrant in SDHB race". Otago Daily Times. Retrieved 27 August 2019. Houlahan, Mike (13 October 2019). "Cull and Chambers top SDHB poll". Otago Daily...
    13 KB (958 words) - 06:15, 28 March 2025
  • Thumbnail for SDHA
    ubiquinol). Electrons removed from succinate transfer to SDHA, transfer across SDHB through iron sulphur clusters to the SDHC/SDHD subunits on the hydrophobic...
    19 KB (2,202 words) - 14:09, 12 August 2024
  • Q9NX18 14435 SDHAF3 HGNC:21752 Q9NRP4 14436 SDHAF4 HGNC:20957 Q5VUM1 14437 SDHB HGNC:10681 P21912 14438 SDHC HGNC:10682 Q99643 14439 SDHD HGNC:10683 O14521...
    282 KB (17 words) - 09:28, 10 February 2025
  • metabolism SDHA NM_004168 Succinate Dehydrogenase subunit A SDHAF2 NM_017841 SDHB NM_002973 Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH)...
    48 KB (4,613 words) - 03:06, 27 May 2025
  • Thumbnail for Anthony Gill (professor)
    Clinicopathologic Series of 36 Tumors From 27 Patients". "Immunohistochemistry for SDHB Divides Gastrointestinal Stromal Tumors (GISTs) into 2 Distinct Types". Cancer...
    5 KB (369 words) - 05:00, 20 March 2023
  • Thumbnail for Gastrointestinal stromal tumor
    pathway involving the succinate dehydrogenase (SDH) subunits SDHD, SDHC and SDHB. Approximately 85% GISTs are associated with an abnormal c-KIT pathway. c-KIT...
    46 KB (4,782 words) - 13:48, 30 April 2025
  • Thumbnail for Fluxapyroxad
    Anastasios N.; Karaoglanidis, George S. (2013). "Differential Effect of SdhB Gene Mutations on the Sensitivity to SDHI Fungicides in Botrytis cinerea"...
    13 KB (1,081 words) - 09:15, 20 September 2024
  • to the protein via four Cys residues. 2Fe–2S: AOX1; FDX1; FDX2; NDUFS1; SDHB; XDH; 4Fe–4S: ABCE1; DPYD; NDUFS8; Mortenson LE, Valentine RC, Carnahan JE...
    32 KB (3,268 words) - 09:51, 22 May 2025
  • transfer in the succinate dehydrogenase complex due to mutations in the SDHB or SDHD genes can cause a build-up of succinate that inhibits HIF prolyl-hydroxylase...
    48 KB (4,885 words) - 05:23, 23 May 2025
  • Health Board (SDHB) also established an emergency operations centre to ensure that staff were able to travel safely to and from work. The SDHB also assisted...
    31 KB (3,445 words) - 09:30, 3 February 2025
  • Thumbnail for Moana Theodore
    Society Te Apārangi. Retrieved 17 June 2023. Houlahan, Mike (9 June 2022). "SDHB meets for last time before restructure". Otago Daily Times. Retrieved 24...
    5 KB (296 words) - 03:12, 21 April 2025
  • Thumbnail for Agriculture in Maryland
    widespread resistance to SDHIs here. They find several etiologies, with various sdhB alleles producing the resistance. H272R resistance to boscalid, H272R or...
    14 KB (1,370 words) - 20:36, 20 July 2024
  • Thumbnail for COVID-19 vaccination in New Zealand
    District Health Board (SDHB) confirmed that mass COVID-19 vaccination clinics would be opened in Dunedin and Invercargill. The SDHB also confirmed that it...
    257 KB (21,015 words) - 19:03, 7 April 2025