Sickle cell trait describes a condition in which a person has one abnormal allele of the hemoglobin beta gene (is heterozygous), but does not display...
26 KB (2,894 words) - 19:29, 25 May 2025
Sickle cell disease (SCD), also simply called sickle cell, is a group of haemoglobin-related blood disorders that are typically inherited. The most common...
131 KB (14,191 words) - 13:43, 27 May 2025
hemoglobin from healthy individuals and those with sickle-cell anemia, with those with sickle cell trait having a mixture of the two types. The paper suggests...
8 KB (996 words) - 13:52, 30 October 2024
Hemoglobin A (section Sickle cell disease)
with the sickle cell trait and about 100 million of those are in sub-Saharan Africa. There is also a higher prevalence of sickle cell trait in areas that...
17 KB (2,067 words) - 20:33, 28 December 2024
relatively benign and like sickle cell trait to being similar to sickle cell disease. Patients with sickle cell-beta thalassemia may present with painful...
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individuals with this type of cancer have sickle cell trait or rarely sickle cell disease, suggesting that the sickle cell trait may be a risk factor for this type...
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Thalassemia (section Red blood cell transfusions)
in common with those who have sickle-cell trait, have some protection against malaria, explaining why sickle-cell trait and thalassemia are historically...
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needed] Sickle-cell disease: 53 Sanfilippo syndrome[citation needed] Tay–Sachs disease: 53 Wet (dominant) or dry (recessive) earwax Most traits (including...
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samples he collected that there was an unusually high occurrence of sickle-cell trait in its less harmful (heterozygous) condition. He conceived the idea...
25 KB (2,887 words) - 20:24, 26 May 2025
Ryan Clark (American football) (category People with sickle-cell disease)
Steelers in Super Bowl XLIII, and made a Pro Bowl in 2011. Clark has a sickle cell trait condition which made it dangerous for him to play at high altitudes...
28 KB (2,392 words) - 23:41, 21 May 2025
"sickle cell crisis" is a sickle cell disease—not the same as sickle cell trait. By itself, the sickle cell trait is not harmful. People with sickle cell...
56 KB (6,715 words) - 05:46, 16 January 2025
Human genetic resistance to malaria (category Cell biology)
by the sickle cell trait". PLOS Medicine. 2 (5): e128. doi:10.1371/journal.pmed.0020128. PMC 1140945. PMID 15916466. Hebbel RP (2003). "Sickle hemoglobin...
75 KB (9,634 words) - 14:30, 23 May 2025
Pleiotropy (section Sickle cell anemia)
provides the fitness benefit of malaria resistance to heterozygotes as sickle cell trait, while homozygotes have significantly lowered life expectancy—what...
50 KB (5,954 words) - 15:15, 25 May 2025
Heterozygote advantage (section Sickle-cell anemia)
sickle cell anaemia. Often, the advantages and disadvantages conveyed are rather complicated, because more than one gene may influence a given trait or...
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However, these heterozygote individuals, known as carriers of the sickle cell trait, may suffer problems from time to time. The heterozygote is resistant...
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accepted into training. During the training, he was diagnosed with sickle cell trait and was removed from training temporarily. Goggins instead participated...
24 KB (1,654 words) - 11:41, 27 May 2025
16, 2025. Portero, Lou (January 20, 2023). "Freshman Dies From Acute Sickle Cell Crisis". Urban Health Today. Retrieved February 16, 2025. "North Carolina...
106 KB (4,210 words) - 11:57, 27 May 2025
Vence L. Bonham Jr. (section Sickle cell disease)
Brody, Lawrence C. (2010-09-09). "Screening student athletes for sickle cell trait--a social and clinical experiment". The New England Journal of Medicine...
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Smokey? Because you are fast?’ But no.” Brown was diagnosed with sickle cell trait in 2016 after suffering from soreness in his hamstrings. He insisted...
37 KB (2,881 words) - 03:04, 17 May 2025
excrete water based on the body's hydration status. Sickle-cell trait, the heterozygous form of sickle-cell disease, presents with a normal hematological picture...
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of sickle cell trait on malaria immunity illustrates some evolutionary trade-offs that have occurred because of endemic malaria. Sickle cell trait causes...
255 KB (26,978 words) - 06:52, 28 May 2025
nose width, in favor of examining blood factors, the presence of the sickle cell trait, lactose intolerance in adults, and other genotype expressions. Excoffier...
18 KB (2,163 words) - 23:14, 25 May 2025
previous exposure or vaccination, or through genetic immunity, such as sickle cell trait conferring resistance to malaria. Other exceptions to Koch's postulates...
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the sickle cell disease to be less severe. In essence the HbF inhibits polymerization of HbS. A similar mechanism occurs with persons who have sickle cell...
5 KB (474 words) - 15:47, 20 September 2021
Plasmodium falciparum (redirect from Plasmodium falciparum cell biology)
including sickle cell trait, thalassaemia traits, glucose-6-phosphate dehydrogenase deficiency, and the absence of Duffy antigens on red blood cells. E. A...
93 KB (10,477 words) - 05:03, 23 May 2025
compared to their mother's cells, which carried the disease trait. Later, it was noted that patients with sickle cell trait as well as hereditary persistence...
38 KB (4,538 words) - 10:54, 4 March 2025
on September 27, 2010. House (Hugh Laurie) treats a patient with sickle cell trait, while dealing with the effects of his burgeoning relationship with...
5 KB (572 words) - 06:50, 4 January 2025
blood cells (e.g., anemia of chronic disease, aplastic anemia); an increased production of HbS as seen in sickle cell disease (not sickle cell trait); an...
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hemoglobin. The test can detect hemoglobin S, the form associated with sickle cell disease, as well as other abnormal types of hemoglobin, such as hemoglobin...
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it may be a symptom of kidney disease, such as IgA nephropathy or Sickle cell trait, or bladder pathology which should be monitored by a doctor. The American...
3 KB (256 words) - 02:58, 21 May 2025