by subfunctionalization, also called "function splitting". In the Duplication- Degeneration- Complementation (DDC) model of subfunctionalization both...

defects are complemented by the other copy. This leads to a neutral "subfunctionalization" (a process of constructive neutral evolution) or DDC...

families. Subfunctionalization Kleinjan DA, Bancewicz RM, Gautier P, Dahm R, Schonthaler HB, Damante G, et al. (February 2008). "Subfunctionalization of duplicated...

activities that can be passed on to the next generation (divergence) "Subfunctionalization" was also first coined by Force et al. 1999. This model requires...

specifically linked to neutrality. A case of CNE is subfunctionalization. The concept of subfunctionalization is that one original (ancestral) gene gives rise...

genes have changed through processes of neofunctionalization or subfunctionalization, meaning their functions are different from what they originally...

an ancestral function. Functional divergence can result in either subfunctionalization, where a paralog specializes one of several ancestral functions,...

evolved genomes. Duplicated genes that diverge in function may undergo subfunctionalization or can become degenerate. When two protein coding genes are degenerate...

genomes, suggesting a diversification through gene duplication and subfunctionalization. Anthozoans display less capsule diversity and a reduced number of...

other classical and recent theories including Muller's ratchet, subfunctionalization, Eigen's concept of an error catastrophe and Lynch's mutational hazard...

nucleotide substitutions cause four amino acid changes and immunological subfunctionalization, can be of one of two types: C4A and C4B. Each gene contains 41 exons...

duplication of the MRFs in invertebrate lineages, similarly followed by subfunctionalization of the expression of the genes in time and/or in space. In amphioxus...

genes may diverge but retain original function by mechanisms such as subfunctionalization, which preserves original gene function albeit by complementary action...

more polyploidization, or genome duplication events. During the subfunctionalization that ensues following gene duplication, there is potential for a...

been argued that this process should be extremely rare and that subfunctionalization better explains the observed distribution. More recently, non-toxic...

and evolution of the tRNA endonucleases of Archaea: an example of subfunctionalization". Proceedings of the National Academy of Sciences of the United States...

proB genes originate from a single gene duplication and subsequent subfunctionalization. The fusion of proA and proB was likely preceded by a deletion of...

EF-1α, on the other hand, performs all functions carried by these subfunctionalized variants. Eukaryotic translation Andersen GR, Nyborg J (2001). "Structural...

paralogous versions of the factor present in bacteria, suggesting subfunctionalization of different EF-G variants. Elongation factors exist in all three...

pressure. The duplicated genes can undergo neofunctionalization, subfunctionalization, or nonfunctionalization which could help the organism adapt to the...

nucleotide substitutions cause four amino acid changes and immunological subfunctionalization, can be of one of two types: C4A and C4B. Each gene contains 41 exons...

P-Loop which binds ATP is absent. It is thought that the MAGUKs have subfunctionalized the GUK domain for their own purposes, primarily based on its ability...

nucleotide substitutions cause four amino acid changes and immunological subfunctionalization (different functions related to the immune system), can be of one...

novo genes originating in this way may not remain overlapping, but subfunctionalize following gene duplication, contributing to the prevalence of orphan...

Freeling M, Scanlon MJ, Fowler JE (December 2015). "Fractionation and subfunctionalization following genome duplications: mechanisms that drive gene content...

P-Loop which binds ATP is absent. It is thought that the MAGUKs have subfunctionalized the GUK domain for their own purposes, primarily based on its ability...

been argued that this process should be extremely rare and that subfunctionalization better explains the observed distribution. More recently, non-toxic...

biogenesis function could be relieved by duplication of Pol II and subfunctionalization of the resulting multiple RNA polymerases. Analyses of evolutionary...

isotopic levels. ASR studies of yeast Adhs reveal that the emergence of subfunctionalized Adhs for ethanol metabolism (not just waste excretion) arose at a...