Nondisjunction is the failure of homologous chromosomes or sister chromatids to separate properly during cell division (mitosis/meiosis). There are three...

called nondisjunction, in which normal cell division is interrupted and produces gametes with too many or too few chromosomes. Nondisjunction is a random...

II. A failure to separate properly is known as nondisjunction. There are two main types of nondisjunction that occur: trisomy and monosomy. Trisomy is caused...

diagnosis is reached. Pentasomy X is not inherited but rather occurs via nondisjunction, a random event in gamete development. In rare cases, it may be related...

nondisjunction event during paternal meiosis I, maternal meiosis I, or maternal meiosis II, also known as gametogenesis. The relevant nondisjunction in...

designation (46,XX). Trisomy 21 (47,XY,+21) is caused by a meiotic nondisjunction event. A typical gamete (either egg or sperm) has one copy of each chromosome...

not caused by characteristics of the parents, but rather occurs via nondisjunction, a random event in gamete development. The karyotype observed in the...

generally not inherited, but rather occurs via a random event called nondisjunction during gamete or zygote development. The formal term for the karyotype...

caused by nondisjunction of chromosomes during meiosis (the mosaic form is caused by nondisjunction during mitosis). Like all nondisjunction conditions...

than two. Trisomy 18 (47,XX,+18) is caused by a meiotic nondisjunction event. In nondisjunction, a pair of chromosomes fails to separate during cell division;...

reproductive cells (eggs and sperm). An error in cell division called nondisjunction results in a reproductive cell with an abnormal number of chromosomes...

when the chromosomes do not separate properly between the two cells (nondisjunction). Most cases of aneuploidy in the autosomes result in miscarriage, and...

termed disjunction. When the segregation is not normal, it is called nondisjunction. This results in the production of gametes which have either too many...

mosaicism can result from many different mechanisms including chromosome nondisjunction, anaphase lag, and endoreplication. Anaphase lagging is the most common...

two X chromosomes and one Y chromosome. This would be caused by two nondisjunction events in spermatogenesis, both meiosis I and meiosis II. The duplicated...

Freeman, S; Sherman, S (1995). "Recombination and maternal age-dependent nondisjunction: molecular studies of trisomy 16". American Journal of Human Genetics...

Medical genetics Usual onset Prenatal Duration Lifelong Causes Cellular nondisjunction during meiosis Diagnostic method Karyotype Frequency 1 in 85,000 to...

ending with the destruction of B cyclin. In order to prevent deleterious nondisjunction events, a key cell cycle checkpoint, the spindle checkpoint, verifies...

successful chromosome segregation. If this does not occur it can result in nondisjunction and aneuploidy. There are several factors that contribute towards failed...

segregation Genetic disorder List of genetic disorders Gene therapy Nondisjunction Obstetrical complications "Chromosomal Abnormalities", Understanding...

can arise due to a number of causes, some of the most common being nondisjunction in parental germ cells or Mendelian inheritance of deleterious alleles...

known as a 'translocation Downs'. This is due to a mis-segregation (nondisjunction) during gametogenesis. The mother has a higher (10%) risk of transmission...

mitosis), resulting in severe errors in their chromosomal complements. In nondisjunction, sister chromatids fail to separate during anaphase. One daughter cell...

taxa result in abnormal pairing between homoeologous chromosomes or nondisjunction during meiosis. In this case, allopolyploidy can actually restore normal...

enjoinment, injunction, injunctive, join, junction, juncture, junta, junto, nondisjunction, nonjoinder, rejoin, rejoinder, sejoin, sejungible, subjoin, subjoinder...

begins to regress and the cells merge. This is thought to be caused by nondisjunction in chromosomes but the mechanism by which it occurs is not well understood...

produce Y gametes, or gametes devoid of any sex chromosome, through nondisjunction. Outside of the rodents, the black muntjac, Muntiacus crinifrons, evolved...

in chromosome separation during anaphase II (of meiosis II) called nondisjunction can result in sperm cells with an extra copy of the Y-chromosome. If...

responsible for maintaining the microtubule system. See anatomy of sperm Nondisjunction—a failure of proper homolog separation in meiosis I, or sister chromatid...

meiosis signalling to germ cells during embryogenesis may result in nondisjunction and monosomy X from not occurred separation of chromosomes in either...