springs and hydrothermal vents, and Taq polymerase was identified as an enzyme able to withstand the protein-denaturing conditions (high temperature)...

bind the RNA polymerase responsible for transcription, either directly or through other mediator proteins; this locates the polymerase at the promoter...

In molecular biology, RNA polymerase (abbreviated RNAP or RNApol), or more specifically DNA-directed/dependent RNA polymerase (DdRP), is an enzyme that...

Protein biosynthesis, or protein synthesis, is a core biological process, occurring inside cells, balancing the loss of cellular proteins (via degradation...

pairing can potentially result in dysfunctional proteins and could lead to cancer. Many DNA polymerases contain an exonuclease domain, which acts in detecting...

eukaryotic DNA polymerases and their accessory proteins". The Journal of Biological Chemistry. 266 (3): 1950–60. doi:10.1016/S0021-9258(18)52385-1. PMID 1671045...

(October 1996). "Influenza virus polymerase basic protein 1 interacts with influenza virus polymerase basic protein 2 at multiple sites". J Virol. 70...

The polymerase chain reaction (PCR) is a method widely used to make millions to billions of copies of a specific DNA sample rapidly, allowing scientists...

recombinant protein under the control of the T7 promoter is 8x faster than protein expression under the control of E. coli RNA polymerase. Basal levels...

TFIIB recruits RNA polymerase II and TFIIF to the promoter. TFIIE joins the growing complex and recruits TFIIH which has protein kinase activity (phosphorylates...

from DNA to messenger RNA. GTFs, RNA polymerase, and the mediator (a multi-protein complex) constitute the basic transcriptional apparatus that first...

Protein phosphatase 1 (PP1) belongs to a certain class of phosphatases known as protein serine/threonine phosphatases. This type of phosphatase includes...

protein to bind to DNA during the formation of the transcription preinitiation complex of RNA polymerase II (RNA Pol II). As one of the few proteins in...

real-time polymerase chain reaction (real-time PCR, or qPCR when used quantitatively) is a laboratory technique of molecular biology based on the polymerase chain...

H and N proteins in the viral envelope; for example, "H1N1" designates an IAV subtype that has a type-1 hemagglutinin (H) protein and a type-1 neuraminidase...

terminators require a large protein called a Rho factor which exhibits RNA helicase activity to disrupt the mRNA-DNA-RNA polymerase transcriptional complex...

in the PR reading frame. The N protein is an antiterminator, and functions by engaging the transcribing RNA polymerase at specific sites of the nascently...

DNA binding proteins are a family of small, usually basic proteins of about 90 residues that bind DNA and are known as histone-like proteins. Since bacterial...

alpha-1. These include the Xenopus protein importin and its yeast homolog, SRP1 (a suppressor of certain temperature-sensitive mutations of RNA polymerase I...

respectively. In the case of a repressor, the repressor protein physically obstructs the RNA polymerase from transcribing the genes. Structural genes – the...

of proteins are associated with the replication fork to help in the initiation and continuation of DNA synthesis. Most prominently, DNA polymerase synthesizes...

phosphorylate serine amino acids on the RNA polymerase II C-terminal domain and possibly other proteins involved in the cell cycle. Next to a vital function...

RNA polymerase and other proteins for the successful initiation of transcription directly upstream of the gene. Operators recognize repressor proteins that...

nuclear ribonucleoprotein K (HNRPK), transcript PABPN1 poly(A) binding protein, nuclear 1 SRSF3 splicing factor, arginine/serine-rich EIF1 aka SUI1 EIF1AD EIF1B...

RNA polymerase from binding and transcribing the DNA; an example of transcription factors up-regulating gene expression is displayed in figure 1 on the...

which RNA polymerase binds and activates transcription through protein-protein interactions with RNA polymerase's α-subunit. This protein-protein interaction...

polymerase requires a host factor, E. coli thioredoxin, in order to carry out its function. This helps stabilize the binding of the necessary protein...

Basic helix-loop-helix ARNT-like protein 1 or aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL), or brain and muscle ARNT-like 1 is...

using the TP protein (rather than RNA) as a primer, so the viral DNA polymerase replicates every base of the genome. Membrane protein E3 RID-alpha and...

Epstein-Barr virus polymerase processivity factor enhances BALF2 promoter transcription as a coactivator for the BZLF1 immediate-early protein. vol 284, iss...