cytosine. Thymine is also known as 5-methyluracil, a pyrimidine nucleobase. In RNA, thymine is replaced by the nucleobase uracil. Thymine was first isolated...
10 KB (888 words) - 00:50, 9 March 2024
Pyrimidine dimer (redirect from Thymine dimer)
Pyrimidine dimers represent molecular lesions originating from thymine or cytosine bases within DNA, resulting from photochemical reactions. These lesions...
16 KB (1,939 words) - 13:32, 25 March 2024
Thymidine (redirect from Thymine deoxyriboside)
(symbol dT or dThd), also known as deoxythymidine, deoxyribosylthymine, or thymine deoxyriboside, is a pyrimidine deoxynucleoside. Deoxythymidine is the DNA...
8 KB (778 words) - 04:54, 16 February 2024
Thymine glycol (5,6-dihydroxy-5,6-dihydrothymine) is one of the principal DNA lesions that can be induced by oxidation and ionizing radiation. The rate...
4 KB (388 words) - 07:41, 22 September 2021
In enzymology, a thymine dioxygenase (EC 1.14.11.6) is an enzyme that catalyzes the chemical reaction thymine + 2-oxoglutarate + O2 ⇌ {\displaystyle \rightleftharpoons...
3 KB (251 words) - 16:03, 26 August 2023
G/T mismatch-specific thymine DNA glycosylase is an enzyme that in humans is encoded by the TDG gene. Several bacterial proteins have strong sequence...
12 KB (1,605 words) - 21:00, 23 December 2023
5,6-Dihydro-5(α-thyminyl)thymine is a DNA pyrimidine dimer photoproduct produced when DNA in bacterial spores is exposed to ultraviolet light. In bacteria...
2 KB (198 words) - 07:43, 17 October 2022
Uracil/thymine dehydrogenase (EC 1.17.99.4, uracil oxidase, uracil-thymine oxidase, uracil dehydrogenase) is an enzyme with systematic name uracil:acceptor...
3 KB (234 words) - 13:55, 27 August 2023
deoxyribonucleic acid (DNA). Five nucleobases—adenine (A), cytosine (C), guanine (G), thymine (T), and uracil (U)—are called primary or canonical. They function as the...
14 KB (1,376 words) - 14:57, 19 May 2024
nitrogen-containing nucleobases (cytosine [C], guanine [G], adenine [A] or thymine [T]), a sugar called deoxyribose, and a phosphate group. The nucleotides...
166 KB (17,845 words) - 02:08, 24 May 2024
four nucleobases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA). It is a pyrimidine derivative, with a heterocyclic aromatic...
10 KB (903 words) - 20:23, 21 May 2024
bonds. In DNA, the uracil nucleobase is replaced by thymine (T). Uracil is a demethylated form of thymine. Uracil is a common and naturally occurring pyrimidine...
29 KB (2,942 words) - 07:58, 6 October 2023
nucleobases in DNA are guanine, adenine, cytosine, and thymine; in RNA, uracil is used in place of thymine. Nucleotides also play a central role in metabolism...
32 KB (3,299 words) - 22:21, 6 May 2024
Messenger RNA (section Uracil substitution for thymine)
uracil (U) instead of thymine (T) in DNA. uracil (U) is the complimentary base to adenine (A) during transcription instead of thymine (T). So when using...
49 KB (5,922 words) - 00:21, 9 May 2024
replication fork, can be corrected by the enzyme thymine-DNA glycosylase, which removes the thymine base in a G/T mismatch. This leaves an abasic site...
6 KB (708 words) - 19:27, 26 May 2023
three types of nucleobases are pyrimidine derivatives: cytosine (C), thymine (T), and uracil (U). The pyrimidine ring system has wide occurrence in...
23 KB (2,105 words) - 06:11, 26 April 2024
between nucleobases: adenine, thymine (uracil in RNA), guanine and cytosine. Adenine and guanine are purines, while thymine, cytosine and uracil are pyrimidines...
23 KB (2,586 words) - 20:09, 27 March 2024
reduce its fidelity. Base analog such as 5-bromouracil may substitute for thymine in replication. Metals such as cadmium, chromium, and nickel can increase...
36 KB (4,334 words) - 23:58, 15 January 2024
nucleic acids of DNA, the other three being guanine (G), cytosine (C), and thymine (T). Adenine derivatives have various roles in biochemistry including cellular...
14 KB (1,317 words) - 08:46, 14 March 2024
5-Methyluridine (redirect from Thymine riboside)
lacks a hydroxyl group at the 2' position. 5-Methyluridine contains a thymine base joined to a ribose pentose sugar. It is a white solid. m5U is one...
4 KB (250 words) - 18:21, 28 April 2024
and break certain types of pyrimidine dimers that arise when a pair of thymine or cytosine bases on the same strand of DNA become covalently linked. The...
15 KB (1,773 words) - 12:32, 2 May 2024
ultraviolet radiation. UVB causes thymine base pairs next to each other in genetic sequences to bond together into thymine dimers, a disruption in the strand...
112 KB (12,375 words) - 15:47, 22 May 2024
Endonuclease (section Thymine dimer repair)
Exposure of bacteriophage (phage) T4 to ultraviolet irradiation induces thymine dimers in the phage DNA. The phage T4 denV gene encodes endonuclease V...
25 KB (2,688 words) - 21:18, 6 April 2024
based on the letters G, A, T, and C, which stand for guanine, adenine, thymine, and cytosine, the four nucleobases of DNA. It was a 1997 nominee for the...
34 KB (3,064 words) - 16:35, 19 May 2024
lesions are general across DNA and RNA, some are specific to one, such as thymine dimers being found exclusively in DNA. Several cellular repair mechanisms...
29 KB (3,548 words) - 20:11, 30 April 2024
binds with thymine and uracil, thymine binds only with adenine, and cytosine and guanine can bind only with one another. Adenine, thymine, and uracil...
59 KB (6,459 words) - 18:28, 6 May 2024
direct DNA damage from UVB light. This damage is mainly the formation of a thymine dimer. The damage is recognized by the body, which then triggers several...
48 KB (5,069 words) - 11:08, 27 April 2024
the nucleic acids DNA and RNA, the others being adenine, cytosine, and thymine (uracil in RNA). In DNA, guanine is paired with cytosine. The guanine nucleoside...
15 KB (1,523 words) - 17:44, 24 February 2024
traditional subcloning. The technique relies on the ability of adenine (A) and thymine (T) (complementary basepairs) on different DNA fragments to hybridize and...
4 KB (477 words) - 19:36, 3 January 2023
determine the order of the four bases: adenine, guanine, cytosine, and thymine. The advent of rapid DNA sequencing methods has greatly accelerated biological...
129 KB (14,413 words) - 04:34, 7 April 2024