protein-coupled receptor 55 also known as GPR55 is a G protein-coupled receptor that in humans is encoded by the GPR55 gene. GPR55, along with GPR119 and GPR18, have...
14 KB (1,699 words) - 20:29, 27 March 2024
"orphan" receptor GPR18. Another possible target of abnormal cannabidiol is GPR55, which has also received much attention as a putative cannabinoid receptor...
9 KB (903 words) - 19:08, 12 April 2024
Other molecular biology studies have suggested that the orphan receptor GPR55 should in fact be characterised as a cannabinoid receptor, on the basis...
32 KB (3,086 words) - 01:45, 9 May 2024
GPR55. Unlike older GPR55 antagonists such as O-1918, PSB-SB-487 has good selectivity over the related receptor GPR18, with an IC50 of 113nM at GPR55...
2 KB (175 words) - 04:24, 25 March 2024
(PPAR-α). PEA also has affinity to cannabinoid-like G-coupled receptors GPR55 and GPR119. PEA cannot strictly be considered a classic endocannabinoid...
51 KB (5,586 words) - 05:10, 1 March 2024
lysophosphatidylinositol (2-ALPI), have been proposed as the endogenous ligands of GPR55. Phosphatidylinositol Cannabinoid receptor Li X, Wang L, Fang P, et al....
3 KB (244 words) - 02:11, 28 March 2024
orphan receptor GPR55, and may be the first selective inverse agonist characterised for this receptor. It was found to block a number of GPR55 mediated responses...
5 KB (518 words) - 07:55, 25 March 2024
Ki values of 0.58 nM and 0.68 nM respectively, but is an antagonist at GPR55, the putative "CB3" receptor. CP 55,940 binding has been detected in the...
6 KB (565 words) - 04:10, 3 January 2024
lessens the psychoactive effects of THC. THCV also acts as an agonist of GPR55 and l-α-lysophosphatidylinositol (LPI), and beyond the endocannabinoid system...
16 KB (1,463 words) - 07:27, 30 April 2024
was found to be an antagonist at the putative new cannabinoid receptor, GPR55, a GPCR expressed in the caudate nucleus and putamen. Cannabidiol has also...
73 KB (7,813 words) - 07:19, 29 April 2024
the extract that contains THCA, and is mediated, at least partially, via GPR55 receptor. The cytotoxic activity of the C. sativa extract was increased...
15 KB (1,623 words) - 23:19, 24 March 2024
CB1Tooltip Cannabinoid receptor type 1 CB2Tooltip Cannabinoid receptor type 2 NAGly (GPR18) GPR55 GPR119...
165 KB (17,217 words) - 11:53, 6 June 2024
CB1Tooltip Cannabinoid receptor type 1 CB2Tooltip Cannabinoid receptor type 2 NAGly (GPR18) GPR55 GPR119...
123 KB (12,044 words) - 22:11, 24 May 2024
receptor that in humans is encoded by the GPR119 gene. GPR119, along with GPR55 and GPR18, have been implicated as novel cannabinoid receptors. GPR119 is...
11 KB (1,172 words) - 04:13, 12 May 2024
(over 36x selectivity vs CB1 and GPR55, and 14x vs CB2.) As all previously known antagonists for GPR18 also antagonise GPR55, it has been difficult to separate...
3 KB (244 words) - 04:24, 25 March 2024
CB1Tooltip Cannabinoid receptor type 1 CB2Tooltip Cannabinoid receptor type 2 NAGly (GPR18) GPR55 GPR119...
123 KB (12,173 words) - 07:22, 23 May 2024
psychoactive, while the others retain activity at targets such as GPR18 and GPR55. Abeo-HHC acetate Abn-CBD CBD-DMH Exo-THC Iso-THC HU-211 Perrottetinene...
5 KB (393 words) - 05:15, 15 January 2024
encoded by the GPR18 gene. Along with the other previously "orphan" receptors GPR55 and GPR119, GPR18 has been found to be a receptor for endogenous lipid neurotransmitters...
10 KB (1,148 words) - 00:02, 3 December 2023
CB1Tooltip Cannabinoid receptor type 1 CB2Tooltip Cannabinoid receptor type 2 NAGly (GPR18) GPR55 GPR119...
70 KB (7,917 words) - 17:29, 2 June 2024
CB1Tooltip Cannabinoid receptor type 1 CB2Tooltip Cannabinoid receptor type 2 NAGly (GPR18) GPR55 GPR119...
95 KB (9,705 words) - 11:51, 6 June 2024
CB1Tooltip Cannabinoid receptor type 1 CB2Tooltip Cannabinoid receptor type 2 NAGly (GPR18) GPR55 GPR119...
24 KB (1,974 words) - 17:08, 16 May 2024
modulator on the CB1 cannabinoid receptor Cannabidiol may be an antagonist of GPR55, a G protein-coupled receptor and putative cannabinoid receptor shown by...
120 KB (11,150 words) - 19:23, 5 May 2024
receptors are known to bind endocannabinoids as well, including GPR18, GPR55 (a regulator of neuroimmune function), and GPR119. CB1 has also been noted...
67 KB (7,709 words) - 06:15, 27 May 2024
a CB2 Ki of 49nM. It is also a weak antagonist at the related receptor GPR55, with an IC50 of 6350nM, but has no significant affinity for GPR18. PSB-SB-487...
2 KB (147 words) - 04:24, 25 March 2024
CB1Tooltip Cannabinoid receptor type 1 CB2Tooltip Cannabinoid receptor type 2 NAGly (GPR18) GPR55 GPR119...
57 KB (5,382 words) - 08:40, 25 May 2024
three novel human G protein-coupled receptor genes GPR52, PsiGPR53 and GPR55: GPR55 is extensively expressed in human brain". Brain Res Mol Brain Res. 64...
3 KB (358 words) - 06:16, 25 April 2024
CB1Tooltip Cannabinoid receptor type 1 CB2Tooltip Cannabinoid receptor type 2 NAGly (GPR18) GPR55 GPR119...
11 KB (985 words) - 23:02, 19 February 2024
CB1Tooltip Cannabinoid receptor type 1 CB2Tooltip Cannabinoid receptor type 2 NAGly (GPR18) GPR55 GPR119...
12 KB (1,160 words) - 16:26, 11 March 2024
CB1Tooltip Cannabinoid receptor type 1 CB2Tooltip Cannabinoid receptor type 2 NAGly (GPR18) GPR55 GPR119...
18 KB (1,783 words) - 01:07, 4 April 2024
CB1Tooltip Cannabinoid receptor type 1 CB2Tooltip Cannabinoid receptor type 2 NAGly (GPR18) GPR55 GPR119...
21 KB (2,059 words) - 07:45, 3 June 2024