• Thumbnail for Nucleoside
    Nucleosides are glycosylamines that can be thought of as nucleotides without a phosphate group. A nucleoside consists simply of a nucleobase (also termed...
    10 KB (851 words) - 01:58, 1 December 2023
  • A nucleoside triphosphate is a nucleoside containing a nitrogenous base bound to a 5-carbon sugar (either ribose or deoxyribose), with three phosphate...
    24 KB (2,528 words) - 15:02, 22 February 2024
  • Thumbnail for Nucleotide
    fundamental, cellular level. They provide chemical energy—in the form of the nucleoside triphosphates, adenosine triphosphate (ATP), guanosine triphosphate (GTP)...
    32 KB (3,299 words) - 22:21, 6 May 2024
  • In enzymology, a nucleoside phosphotransferase (EC 2.7.1.77) is an enzyme that catalyzes the chemical reaction a nucleotide + a 2'-deoxynucleoside ⇌ {\displaystyle...
    2 KB (165 words) - 15:12, 26 August 2023
  • Thumbnail for Nucleoside analogue
    Nucleoside analogues are structural analogues of a nucleoside, which normally contain a nucleobase and a sugar. Nucleotide analogues are analogues of...
    7 KB (716 words) - 08:42, 17 October 2023
  • Thumbnail for Arabinosyl nucleoside
    Arabinosyl nucleosides are derivatives of the nucleosides. They contain β-D-arabinofuranose, in contrast to most nucleosides which contain β-D-ribofuranose...
    1 KB (105 words) - 16:37, 21 February 2024
  • to as polymerase inhibitors.[citation needed] RTIs come in four forms: Nucleoside analog reverse-transcriptase inhibitors (NARTIs or NRTIs) Nucleotide analog...
    25 KB (2,906 words) - 07:02, 4 April 2024
  • Thumbnail for Nucleoside transporter
    Nucleoside transporters (NTs) are a group of membrane transport proteins which transport nucleoside substrates like adenosine across the membranes of...
    3 KB (222 words) - 14:39, 11 May 2023
  • Thumbnail for Nucleoside deoxyribosyltransferase
    In enzymology, a nucleoside deoxyribosyltransferase (EC 2.4.2.6) is an enzyme that catalyzes the chemical reaction 2-deoxy-D-ribosyl-base1 + base2 ⇌ {\displaystyle...
    3 KB (259 words) - 17:58, 23 January 2024
  • Thumbnail for Purine nucleoside phosphorylase
    Purine nucleoside phosphorylase, PNP, PNPase or inosine phosphorylase (EC 2.4.2.1) is an enzyme that in humans is encoded by the NP gene. It catalyzes...
    14 KB (1,511 words) - 15:37, 26 August 2023
  • Synthesis of nucleosides involves the coupling of a nucleophilic, heterocyclic base with an electrophilic sugar. The silyl-Hilbert-Johnson (or Vorbrüggen)...
    14 KB (1,781 words) - 01:16, 25 March 2021
  • Thumbnail for Nucleoside phosphoramidite
    Nucleoside phosphoramidites are derivatives of natural or synthetic nucleosides. They are used to synthesize oligonucleotides, relatively short fragments...
    25 KB (2,992 words) - 12:18, 16 January 2024
  • showed how pyrimidine nucleosides can be synthesized from small molecules and ribose, driven solely by wet-dry cycles. Purine nucleosides can be synthesized...
    23 KB (2,105 words) - 06:11, 26 April 2024
  • Thumbnail for Nucleoside-diphosphatase
    In enzymology, a nucleoside-diphosphatase (EC 3.6.1.6) is an enzyme that catalyzes the chemical reaction a nucleoside diphosphate + H2O ⇌ {\displaystyle...
    3 KB (269 words) - 15:12, 26 August 2023
  • Nucleoside oxidase (EC 1.1.3.28) is an enzyme with systematic name nucleoside:oxygen 5'-oxidoreductase. This enzyme catalyses the following chemical reaction...
    2 KB (143 words) - 15:12, 26 August 2023
  • diphosphate-purine nucleoside kinase (EC 2.7.1.143) is an enzyme that catalyzes the chemical reaction diphosphate + a purine nucleoside ⇌ {\displaystyle...
    2 KB (158 words) - 13:52, 26 August 2023
  • Members of the Equilibrative Nucleoside Transporter (ENT) Family (TC# 2.A.57) are transport proteins that are specific to nucleosides and nucleobases, and are...
    6 KB (635 words) - 12:33, 24 January 2024
  • Thumbnail for Nucleoside-diphosphate kinase
    Nucleoside-diphosphate kinases (NDPKs, also NDP kinase, (poly)nucleotide kinases and nucleoside diphosphokinases) are enzymes that catalyze the exchange...
    20 KB (2,538 words) - 07:18, 20 September 2023
  • Thumbnail for Purine nucleosidase
    purine nucleoside + H2O ⇌ {\displaystyle \rightleftharpoons } D-ribose + a purine base Thus, the two substrates of this enzyme are purine nucleoside and...
    4 KB (405 words) - 15:37, 26 August 2023
  • Thumbnail for Nucleoside-triphosphatase
    In enzymology, a nucleoside-triphosphatase (NTPase) (EC 3.6.1.15) is an enzyme that catalyzes the chemical reaction NTP + H2O ⇌ {\displaystyle \rightleftharpoons...
    3 KB (215 words) - 20:56, 25 January 2024
  • } nucleoside diphosphate + ADP Thus, the two substrates of this enzyme are nucleoside triphosphate and AMP, whereas its two products are nucleoside diphosphate...
    2 KB (200 words) - 15:12, 26 August 2023
  • Thumbnail for Cidofovir
    Cidofovir, brand name Vistide, is a topical or injectable antiviral medication primarily used as a treatment for cytomegalovirus (CMV) retinitis (an infection...
    15 KB (1,352 words) - 23:05, 17 April 2024
  • A nucleoside-modified messenger RNA (modRNA) is a synthetic messenger RNA (mRNA) in which some nucleosides are replaced by other naturally modified nucleosides...
    24 KB (2,503 words) - 11:29, 22 February 2024
  • Thumbnail for NS5B inhibitor
    inhibitors may be categorized into three classes—nucleoside active site inhibitors (NIs), non-nucleoside allosteric inhibitors, and pyrophosphate analogues...
    33 KB (3,798 words) - 21:57, 16 May 2024
  • Thumbnail for Adenosine triphosphate
    kilograms daily. From the perspective of biochemistry, ATP is classified as a nucleoside triphosphate, which indicates that it consists of three components: a...
    48 KB (5,275 words) - 09:38, 7 May 2024
  • Human concentrative nucleoside transporters include SLC28A1, SLC28A2 and SLC28A3 proteins. SLC28A2 is a purine-specific Na+-nucleoside cotransporter localised...
    2 KB (150 words) - 02:08, 29 November 2023
  • dG, and T), ribonucleosides (A, C, G, and U), or chemically modified nucleosides, e.g. LNA or BNA. To obtain the desired oligonucleotide, the building...
    79 KB (9,462 words) - 18:31, 28 January 2024
  • Thumbnail for Nucleoside-specific porin
    Nucleoside-specific porin (the tsx gene of Escherichia coli) is an outer membrane protein, Tsx, which constitutes the receptor for colicin K and Bacteriophage...
    1 KB (125 words) - 03:02, 29 November 2023
  • Typical combinations include two nucleoside reverse-transcriptase inhibitors (NRTI) as a "backbone" along with one non-nucleoside reverse-transcriptase inhibitor...
    134 KB (15,824 words) - 14:29, 11 April 2024
  • Thumbnail for Nucleobase
    simply bases) are nitrogen-containing biological compounds that form nucleosides, which, in turn, are components of nucleotides, with all of these monomers...
    14 KB (1,376 words) - 14:57, 19 May 2024