U.S. Highway 8 (US 8) is a United States Numbered Highway that runs primarily east–west for 280 miles (451 km), mostly within the state of Wisconsin. It...

U.S. Route 150 (US 150) is a 571-mile (919 km) long northwest–southeast United States highway, signed as east–west. It runs from U.S. Route 6 outside...

U.S. Route 66 or U.S. Highway 66 (US 66 or Route 66) was one of the original highways in the United States Numbered Highway System. It was established...

U.S. Route 31E (US 31E) is the eastern parallel route for U.S. Highway 31 from Nashville, Tennessee, to Louisville, Kentucky. US 31E begins as the Ellington...

U.S. Route 167 is a north-south United States Highway within the U.S. states of Louisiana and Arkansas. It runs for 500 miles (800 km) from Ash Flat, Arkansas...

U.S. Route 321 (US 321) is a spur of U.S. Route 21. It runs for 516.9 miles (831.9 km) from Hardeeville, South Carolina to Lenoir City, Tennessee; with...

U.S. Route 501 (US 501) is a spur of U.S. Route 1. It runs 355 miles (571 km) from Buena Vista, Virginia at U.S. Route 60 to Myrtle Beach, South Carolina...

U.S. Route 310 (US 310) is a spur of historic U.S. Route 10, now Interstate 90. It runs for 108 miles (174 km) from Laurel, Montana, to Greybull, Wyoming...

U.S. Route 136 is an east-west U.S. highway that is a spur route of U.S. Route 36. It runs from Edison, Nebraska, at U.S. Route 6 and U.S. Route 34 to...

U.S. Route 412 is an east–west United States highway, first commissioned in 1982. U.S. 412 overlaps expressway-grade Cimarron Turnpike from Tulsa west...

U.S. Route 53, or U.S. Highway 53 (U.S. 53), is a north–south U.S. highway that runs for 404 miles (650 km) from La Crosse, Wisconsin to International...

Several special routes of U.S. Route 64 exist. In order from west to east they are as follows. U.S. Route 64 Alternate (US 64 Alt) was established in 1979...

U.S. Route 283 is a spur of U.S. Route 83. It currently runs for 731 miles (1,175 km) from Brady, Texas at U.S. Route 87 to Lexington, Nebraska at U.S...

U.S. Route 160 (US 160) is a 1,465-mile-long (2,358 km) east–west United States Numbered Highway in the Midwestern and Western United States. The western...

U.S. Route 165 is a north–south United States highway spur of U.S. Highway 65. It currently runs for 412 miles (663 km) from U.S. Route 90 in Iowa, Louisiana...

U.S. Route 371 is a north–south United States highway in the U.S. states of Arkansas and Louisiana. The highway's northern terminus is in De Queen, Arkansas...

U.S. Route 50 or U.S. Highway 50 (US 50) is a major east–west route of the U.S. Highway system, stretching 3,019 miles (4,859 km) from Interstate 80 (I-80)...

U.S. Route 277 (US 277, US-277) is a north–south United States Highway that is a spur route of U.S. Route 77. It no longer connects to its parent route...

U.S. Route 49 (US 49) is a north–south United States highway. The highway's northern terminus is in Piggott, Arkansas, at an intersection with US Route...

U.S. Route 59 (US 59) is a north–south United States highway (though it was signed east–west in parts of Texas). A latecomer to the U.S. numbered route...

U.S. Route 601 (US 601) is a north–south United States highway that runs for 316.3 miles (509.0 km) from U.S. Route 321, near Tarboro, South Carolina...

U.S. Route 380 (US 380) is an east–west United States highway. The highway's eastern terminus is in Greenville, Texas at an intersection with Interstate...

connects U.S. Route 62 U.S. Route 75 (US 62/US 75) in Henryetta with U.S. Route 64 (US 64) in Warner. The highway no longer meets the former route of its...

U.S. Route 70 or U.S. Highway 70 (US 70) is an east–west United States highway that runs for 2,381 miles (3,832 km) from eastern North Carolina to east-central...

U.S. Route 301 (US 301) is a spur of U.S. Route 1 running through the South Atlantic states. It runs 1,099 miles (1,769 km) from Biddles Corner, Delaware...

U.S. Route 140 (Pennsylvania "Legislative Route 42") was a U.S. highway connecting Gettysburg, Pennsylvania, to Baltimore, Maryland. The route was deleted...

U.S. Route 93 (US 93) is a major north–south 1,359-mile (2,187 km) U.S. Numbered Highway in the western United States, that connects U.S. Route 60 (US 60)...

U.S. Route 275 (US 275) is a north–south United States highway that is a branch of US 75. It originally terminated at US 75 in Council Bluffs, Iowa. The...

U.S. Route 1A (US 1A) is the name of several highways found in the United States. U.S. Highway 1A (US 1A) is a 9.0-mile (14.5 km) alternate route of US 1...

Several special routes of U.S. Route 29 (US 29) exist. In order from south to north, they are as follows. U.S. Route 29 Truck (US 29 Truck) is a 1.025-mile-long...