• Thumbnail for CRISPR
    debate. CRISPR activation Anti-CRISPR CRISPR/Cas Tools CRISPR gene editing The CRISPR Journal "Designer baby" DRACO Gene knockout Genome-wide CRISPR-Cas9...
    115 KB (11,900 words) - 21:51, 4 June 2025
  • Thumbnail for CRISPR gene editing
    Chemistry, "for the development of a method for genome editing." Biology portal Technology portal CRISPR/Cas Tools The CRISPR Journal Eugenics DRACO Zinc finger...
    177 KB (20,524 words) - 22:37, 29 May 2025
  • (gRNAs) for use with the CRISPR/Cas gene editing system. The CRISPR/Cas (clustered regularly interspaced short palindromic repeats/CRISPR associated nucleases)...
    16 KB (1,283 words) - 21:43, 2 January 2025
  • Thumbnail for Human genetic enhancement
    genetic disorders. Gene treatment employing the CRISPR/Cas genome editing method is known as CRISPR/Cas-based gene therapy. Mammalian cells can be genetically...
    93 KB (10,228 words) - 20:00, 16 May 2025
  • Thumbnail for Cas9
    Cas9 (redirect from CRISPR/Cas9)
    have evolved methods to evade and fend off predatory viruses. This includes the CRISPR system of adaptive immunity. In practice, CRISPR/Cas systems act...
    59 KB (7,257 words) - 12:01, 9 June 2025
  • Thumbnail for Kōji (food)
    irradiation or by the CRISPR/CAS method. Similarly, mutants of A. sojae with altered properties were generated by a variant of the CRISPR/Cas method or chemical...
    28 KB (3,556 words) - 14:26, 8 June 2025
  • CRISPR activation (CRISPRa) is a gene regulation technique that utilizes an engineered form of the CRISPR-Cas9 system to enhance the expression of specific...
    22 KB (2,739 words) - 08:03, 1 April 2025
  • Thumbnail for Cas12a
    Cas12a (redirect from CRISPR/Cas12a)
    the host cell from infection. Like other Cas enzymes, Cas12a binds to a "guide" RNA (termed a crRNA, or CRISPR RNA) which targets it to a DNA sequence...
    22 KB (2,638 words) - 01:38, 9 June 2025
  • Thumbnail for CRISPR interference
    adaptive immune system which incorporates CRISPR RNA (crRNA) and CRISPR-associated (cas) genes. The CRISPR interference (CRISPRi) technique was first...
    24 KB (2,898 words) - 12:08, 22 March 2024
  • enzyme CRISPR-associated (Cas) proteins, involved in the prokaryotic immune system and genome editing CAS parameters, an image analysis method typically...
    7 KB (843 words) - 13:25, 16 February 2025
  • Thumbnail for Anti-CRISPR
    in phages, that inhibit the normal activity of CRISPR-Cas, the immune system of certain bacteria. CRISPR consists of genomic sequences that can be found...
    32 KB (3,690 words) - 10:49, 25 May 2025
  • patterning that mimic loss of wingless function. CRISPR/Cas is primarily used for reverse genetic screens. CRISPR has the ability to create libraries of thousands...
    18 KB (2,199 words) - 17:53, 21 April 2024
  • Cas-proteins that cut the double-stranded DNA and thereby can be used for gene editing. In bacteria and archaea, gRNAs are a part of the CRISPR-Cas system...
    30 KB (3,644 words) - 14:03, 23 May 2025
  • Thumbnail for Genetic engineering techniques
    more complicated method of such as Golden gate cloning. In 2011, another major breakthrough technology was developed based on CRISPR/Cas (clustered regularly...
    55 KB (6,765 words) - 11:43, 11 December 2024
  • Thumbnail for Gene targeting
    engineered homing endonucleases, TALENS, or most commonly the CRISPR-Cas system. This method has been applied to species including Drosophila melanogaster...
    40 KB (4,473 words) - 03:37, 8 April 2025
  • Thumbnail for Jennifer Doudna
    February 19, 1964) is an American biochemist who has pioneered work in CRISPR gene editing, and made other fundamental contributions in biochemistry and...
    70 KB (5,988 words) - 04:17, 10 June 2025
  • Thumbnail for Genome editing
    engineered meganucleases—were selected by Nature Methods as the 2011 Method of the Year. The CRISPR-Cas system was selected by Science as 2015 Breakthrough...
    79 KB (9,365 words) - 19:52, 22 May 2025
  • Thumbnail for Francisco Mojica
    Heroes of CRISPR) Mojica, Francisco J. M.; Garrett, Roger A. (13 December 2012). "Discovery and Seminal Developments in the CRISPR Field". CRISPR-Cas Systems...
    20 KB (1,955 words) - 15:49, 15 October 2023
  • while exerting no aberrant effects on wild-type alleles. CRISPR CRISPR/Cpf1 Addgene CRISPR-Cas Guide Shah SA, Erdmann S, Mojica FJ, Garrett RA (2013)....
    12 KB (1,422 words) - 22:27, 13 June 2025
  • or CRISPRs. CRISPR-associated (cas) genes encode cellular machinery that cuts exogenous DNA into small fragments and inserts them into a CRISPR repeat...
    13 KB (1,611 words) - 03:43, 8 April 2025
  • Thumbnail for Feng Zhang
    Philippe; Magadán, Alfonso H.; Moineau, Sylvain (November 4, 2010). "The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA". Nature...
    27 KB (2,302 words) - 03:19, 3 June 2025
  • Thumbnail for Insertion (genetics)
    nucleases (TALEN), and CRISPR gene editing are the three main methods used in the former research to achieve gene insertion. And CRISPR/Cas tools have already...
    8 KB (940 words) - 02:53, 25 May 2025
  • Thumbnail for GESTALT
    labeling. There are multiple methods of delivering the CRISPR-Cas9 reagents into cells and it is an active field of research. CRISPR-Cas9 reagents can be introduced...
    23 KB (2,712 words) - 21:52, 22 May 2025
  • organism's genome. This can be done through a variety of methods, including homologous recombination, CRISPR-Cas9, and TALENs. One of the main advantages of gene...
    22 KB (2,563 words) - 23:23, 24 May 2025
  • alternatives that can limit the off-target burden when possible. CRISPR-cas13b, using a type IV CRISPR-Cas system (as opposed to the commonly used type II) can target...
    55 KB (7,122 words) - 04:03, 28 April 2025
  • Thumbnail for Genome-wide CRISPR-Cas9 knockout screens
    Genome-wide CRISPR-Cas9 knockout screens aim to elucidate the relationship between genotype and phenotype by ablating gene expression on a genome-wide...
    55 KB (6,172 words) - 00:49, 29 May 2025
  • Thumbnail for Germline mutation
    Center. Retrieved 23 September 2018. Sander JD, Joung JK (April 2014). "CRISPR-Cas systems for editing, regulating and targeting genomes". Nature Biotechnology...
    25 KB (3,085 words) - 03:46, 17 September 2024
  • Thumbnail for Designer baby
    trait. Other methods of altering a baby's genetic information involve directly editing the genome before birth, using technologies such as CRISPR. A controversial...
    78 KB (8,906 words) - 17:45, 13 June 2025
  • CRISPR-Display (CRISP-Disp) is a modification of the CRISPR/Cas9 (Clustered regularly interspaced short palindromic repeats) system for genome editing...
    16 KB (2,133 words) - 12:04, 22 March 2024
  • Thumbnail for LEAPER gene editing
    DNA and thus does not result in heritable changes, unlike methods using CRISPR Cas-9. CRISPR gene editing Gene knockout NgAgo Prime editing Murphy F, Walsh...
    7 KB (783 words) - 12:15, 22 February 2024