• Bone marrow suppression also known as myelotoxicity or myelosuppression, is the decrease in production of cells responsible for providing immunity (leukocytes)...
    8 KB (831 words) - 04:05, 28 February 2024
  • myelosuppression. ++ means 30-70% of patients exhibit significant myelosuppression. + means 10-30% of patients exhibit significant myelosuppression....
    23 KB (742 words) - 04:57, 30 December 2023
  • Thumbnail for Chemotherapy
    follicles. This results in the most common side-effects of chemotherapy: myelosuppression (decreased production of blood cells, hence that also immunosuppression)...
    154 KB (17,496 words) - 07:54, 6 June 2024
  • Thumbnail for Scleroderma
    lymphocyte proliferation via conversion to mercaptopurine PO, IV D (Au) Myelosuppression and rarely malignancy, hepatitis, infection, hepatic sinusoidal obstruction...
    38 KB (3,291 words) - 01:18, 9 May 2024
  • Myelodysplastic syndromes, acute myeloid leukaemia and chronic myeloid leukaemia Myelosuppression, kidney failure (uncommon/rare), renal tubular acidosis and hypokalaemia...
    52 KB (708 words) - 00:21, 11 April 2024
  • Thumbnail for Thalidomide
    substantially more powerful and have fewer side effects — except for greater myelosuppression. In 2005, Celgene received FDA approval for lenalidomide (Revlimid)...
    76 KB (7,473 words) - 17:46, 5 June 2024
  • Thumbnail for Capecitabine
    Hair loss Dermatitis Indigestion Shortness of breath Eye irritation Myelosuppression Notes on adverse effects: Includes: anaemia, lymphopenia, neutropenia...
    14 KB (1,103 words) - 04:38, 5 April 2024
  • part of SCLC treatment frequently experience chemotherapy-induced myelosuppression. In three randomized, placebo-controlled SCLC trials, trilaciclib,...
    20 KB (2,065 words) - 01:40, 29 December 2023
  • mycobacterium avium complex (MAC) – mycosis – myelin – myelopathy – myelosuppression – myelotoxic – myocardial – myopathy NAT – National Cancer Institute...
    23 KB (1,720 words) - 22:45, 3 January 2023
  • Thumbnail for Atovaquone
    TMP-SMX. In addition, atovaquone has the advantage of not causing myelosuppression, which is an important issue in patients who have undergone bone marrow...
    11 KB (880 words) - 06:06, 11 May 2024
  • Thumbnail for SN-38
    the bile and intestines. It can cause the symptoms of diarrhoea and myelosuppression experienced by ~25% of the patients administered irinotecan. Click...
    3 KB (225 words) - 16:48, 11 January 2024
  • Thumbnail for Tyrosine kinase inhibitor
    treatment of refractory solid tumors. However, toxicities such as myelosuppression, diarrhea, and supraventricular tachyarrhythmia have arisen while attempting...
    9 KB (1,081 words) - 04:46, 16 June 2022
  • Thumbnail for Carboplatin
    sometimes as low as 10% of its usual production levels. The nadir of this myelosuppression usually occurs 21–28 days after the first treatment, after which the...
    15 KB (1,438 words) - 02:57, 10 May 2024
  • Thumbnail for Azathioprine
    metabolites and an increased risk of severe bone marrow suppression (myelosuppression) when receiving azathioprine. In many ethnicities, TPMT polymorphisms...
    54 KB (5,481 words) - 17:52, 29 April 2024
  • failure 2% Neuroendocrine hormonal crisis Hypotension 1% Bronchospasm Myelosuppression 1% Lymphopenia 44% Anemia Thrombocytopenia Leukopenia Neutropenia Cardiac...
    17 KB (1,540 words) - 20:14, 20 August 2022
  • Diarrhea (see below for details) Mucositis Headache Hand-foot syndrome Myelosuppression (see below for details) Alopecia (hair loss) Photosensitivity Maculopapular...
    31 KB (2,770 words) - 04:10, 13 February 2024
  • Thumbnail for Lenalidomide
    bone marrow toxicity resulting in neutropenia and thrombocytopenia. Myelosuppression is the major dose-limiting toxicity, which is not the case with thalidomide...
    28 KB (2,346 words) - 06:09, 6 May 2024
  • Angioedema Drug fever Periarteritis nodosa Hepatic necrosis Pancreatitis Myelosuppression Haemolysis Stevens–Johnson syndrome Drug reaction with eosinophilia...
    5 KB (355 words) - 07:21, 19 May 2024
  • Thumbnail for Multiple myeloma
    effects of thalidomide and lenalidomide. Lenalidomide causes more myelosuppression, and thalidomide causes more sedation. Chemotherapy-induced peripheral...
    131 KB (13,418 words) - 12:28, 5 June 2024
  • Thumbnail for Dasatinib
    swelling in the legs and arms and in the face, fever. Neutropenia and myelosuppression were common toxic effects. Fifteen people (of 84, i.e. 18%) in the...
    22 KB (1,994 words) - 04:41, 3 January 2024
  • Thumbnail for Enhancer (genetics)
    been shown to be involved in certain medical conditions, for example, myelosuppression. Since 2022, scientists have used artificial intelligence to design...
    51 KB (5,914 words) - 03:06, 4 June 2024
  • Thumbnail for Donkey-hide gelatin
    collagen in the hide. This effect may benefit cancer patients with myelosuppression due to radiotherapy or chemotherapy. Animal glue / Hide glue Jing-Nuan...
    11 KB (1,216 words) - 04:20, 6 May 2024
  • Thumbnail for Omacetaxine mepesuccinate
    omacetaxine. By frequency: Very common (>10% frequency): Diarrhoea Myelosuppression† Injection site reactions Nausea Fatigue Fever Muscle weakness Joint...
    9 KB (778 words) - 09:37, 2 June 2023
  • Thumbnail for Tegafur
    major side effects of tegafur are similar to fluorouracil and include myelosuppression, central neurotoxicity and gastrointestinal toxicity (especially diarrhoea)...
    8 KB (621 words) - 12:45, 8 December 2023
  • Chemotherapy frequently causes vomiting, nausea, alopecia, mucositis, myelosuppression particularly neutropenia, sometimes resulting in septicaemia. Some...
    37 KB (4,655 words) - 16:47, 30 May 2024
  • Thumbnail for Vincristine
    diabetes mellitus were disappointing, the discovery that it caused myelosuppression (decreased activity of the bone marrow) led to its study in mice with...
    31 KB (2,816 words) - 15:19, 16 May 2024
  • Thumbnail for Bortezomib
    can be worse in people with pre-existing neuropathy. In addition, myelosuppression causing neutropenia and thrombocytopenia can also occur and be dose-limiting...
    24 KB (2,176 words) - 20:17, 26 January 2024
  • Thumbnail for Anthracycline
    anthracyclines include myelosuppression and cardiotoxicity. Fortunately, the introduction of therapeutic cytokines allows management of myelosuppression. Hence, cardiac...
    46 KB (5,057 words) - 13:18, 23 May 2024
  • Hypersensitivity reactions (e.g. itchiness, contact dermatitis, and hives) Myelosuppression Gastrointestinal effects (e.g. nausea, vomiting, and diarrhoea) Headache...
    13 KB (1,034 words) - 23:41, 23 March 2024
  • Thumbnail for Cyclin-dependent kinase
    during cancer treatment by reducing the risk of chemotherapy-induced myelosuppression, a common side effect that can lead to treatment delays and dose reductions...
    35 KB (3,829 words) - 23:39, 22 April 2024