α-Amanitin (alpha-Amanitin) is a cyclic peptide of eight amino acids. It is possibly the most deadly of all the amatoxins, toxins found in several species...

Amanitin may refer to several related amatoxins: α-Amanitin β-Amanitin γ-Amanitin ε-Amanitin Amatoxin, a class of toxic compounds that include the amanitins...

 virosa and A. bisporigera. Due to the presence of α-Amanitin, β-Amanitin, γ-Amanitin and epsilon-Amanitin these mushrooms are highly lethal to human beings...

the University of Munich. Of the amatoxins, α-Amanitin is the chief component and along with β-amanitin is likely responsible for the toxic effects....

transcribing polymerase. RNA polymerase II is inhibited by α-Amanitin and other amatoxins. α-Amanitin is a highly poisonous substance found in many mushrooms...

Three subtypes of amatoxin have been described: α-, β, and γ-amanitin. The principal amatoxin, α-amanitin, is readily absorbed across the intestine, and...

repair damage and the cells of the liver die off quickly. Alpha-amanitin (α-Amanitin) primarily affects the bridge helix of the RNA pol II complex, a...

about 50% on its own. The most potent toxin present in these mushrooms is α-Amanitin. The genus also contains many edible mushrooms, but mycologists discourage...

sensitive to heat and so are not broken down during cooking; in particular, α-Amanitin, the poison produced by the death cap (Amanita phalloides) and others...

hepatic and tubular necrosis. γ-Amanitin has been found to have similar levels of toxicity to other amatoxins such as α-Amanitin. Mushroom poisoning PubChem...

for several poisonings in California. Its principal toxic constituent, α-Amanitin, damages the liver and kidneys, often fatally, and has no known antidote...

the University of Munich. Of the amatoxins, α-Amanitin is the chief component and along with β-Amanitin is probably responsible for the toxic effects...

known to be synthesized by an organism in the animal kingdom. The toxin α-amanitin is found in numerous, seemingly unrelated genera fungi such as Amanita...

marginata was shown in various studies to contain the amatoxins α-amanitin and γ-amanitin, first as G. venenata, then as G. marginata and G. autumnalis...

"Identification of indocyanine green as a STT3B inhibitor against mushroom α-amanitin cytotoxicity". Nature Communications. 14 (1): 2241. doi:10.1038/s41467-023-37714-3...

C-terminal recognition sequence in addition to the N-terminal leader peptide. α-Amanitin, an amatoxin, has a number of posttranslational modifications in addition...

two side chains or more complicated arrangements, for example in alpha-amanitin. Many cyclic peptides have been discovered in nature and many others have...

chromatography column. And also combinations of the above techniques. Alpha-amanitin Primase Werner F, Grohmann D (February 2011). "Evolution of multisubunit...

αI, αII, and ω subunits of E. coli RNA polymerase. An identical ω-like subunit (RBP6) is used by all three eukaryotic polymerases, while the same α-like...

Alpha-amanitin Alpha-MSH (Melaninocyte stimulating hormone) Allantoin Allethrin α-Amanatin, see Alpha-amanitin Amino acid Amylase (also see α-amylase)...

rates are measured by means of transcription inhibitors (actinomycin D or α-Amanitin) or translation inhibitors (Cycloheximide), respectively. Artificial transcription...

Hermanowicz P, et al. (2017). "Selection and analysis of a DNA aptamer binding α-amanitin from Amanita phalloides". Acta Biochimica Polonica. 64 (3): 401–406. doi:10...

toxins, termed α, β, γ, δ and ε-latroinsectotoxins, one vertebrate-specific neurotoxin, alpha-latrotoxin, and one toxin affecting crustaceans, α-latrocrustatoxin...

Kornberg, Roger D. (5 February 2002). "Structural basis of transcription: α-Amanitin–RNA polymerase II cocrystal at 2.8 Å resolution". Proceedings of the National...

mollusks and fly larvae, some of which are even tolerant to the toxic α-amanitin found in death caps. Below ground, nematodes and springtails also consume...

a high ratio of ALT to ALP, and cholestatic injury by a lower ratio. α-amanitin, a deadly cellular toxin found in Amanita phalloides mushroom (death cap)...

cytotoxins, cardiotoxins, and postsynaptic neurotoxins (such as α-bungarotoxin and α-Cobratoxin), which bind to acetylcholine receptors at neuromuscular...

RNA polymerase from Saccharomyces cerevisiae complexed with α-Amanitin (in red). Despite the use of the term "polymerase," RNA polymerases are classified...

α-Bungarotoxin is one of the bungarotoxins, components of the venom of the elapid Taiwanese banded krait snake (Bungarus multicinctus). It is a type of...

most notably Agaricus campestris. The principal toxic constituent is α-Amanitin, an elective inhibitor of RNA polymerase II and III, which causes liver...