α-Catenin (alpha-catenin) functions as the primary protein link between cadherins and the actin cytoskeleton. It has been reported that the actin binding...

identified became known as α-catenin and β-catenin. α-Catenin can bind to β-catenin and can also bind filamentous actin (F-actin). β-Catenin binds directly to...

Catenin beta-1, also known as β-catenin (beta-catenin), is a protein that in humans is encoded by the CTNNB1 gene. β-Catenin is a dual function protein...

the actomyosin cytoskeleton. p120-catenin controls E-cadherin membrane localization, while β-catenin and α-catenin provide the link that connect AJs to...

junctions. α-catenin and β-catenin are integral components of adherens junctions, which bind together to produce cadherin-α-catenin-β-catenin complexes...

catenin) binds the juxtamembrane region of the cadherin. γ-catenin or gamma-catenin (plakoglobin) binds the catenin-binding region of the cadherin. α-catenin...

intracellular catenin proteins, specifically the three different subtypes, α-catenins, β-catenins, and p120ctn family catenins. β-catenins and p120ctns...

Catenin alpha-2, also known as αN-catenin, is a type of α-catenin protein that in humans is encoded by the CTNNA2 gene. Claverie JM, Hardelin JP, Legouis...

Catenin alpha-3, also known as αT-catenin, is a α-catenin protein that in humans is encoded by the CTNNA3 gene. Janssens B, Goossens S, Staes K, Gilbert...

CL, Nelson WJ, Smith SJ (Dec 1996). "Quantitative analysis of cadherin-catenin-actin reorganization during development of cell-cell adhesion". The Journal...

of the cell. This allows for homophilic cell–cell adhesion. The β-catenin–α-catenin linked complex at the adherens junctions allows for the formation...

its sequence is 20%–30% similar to α-catenin, which serves a similar function. Binding alternately to talin or α-actinin, vinculin's shape and, as a...

T, Weiss TM, Stanley CB, Heller WT, Martel A, et al. (August 2018). "α-Catenin Structure and Nanoscale Dynamics in Solution and in Complex with F-Actin"...

HTR2B a serotonin receptor gene. CTNNA2 encodes for a brain-expressed α-catenin that has been associated with Excitement-Seeking in a genome-wide association...

Toksoz D (2004). "Distinct Activities of the α-Catenin Family, α-Catulin and α-Catenin, on β-Catenin-Mediated Signaling". Mol. Cell. Biol. 24 (6): 2410–22...

αE-catenin, also known as Catenin alpha-1 is a protein that in humans is encoded by the CTNNA1 gene. αE-catenin is highly expressed in cardiac muscle...

forming an adhesion complex. This adhesion complex is formed by β-catenin and α-catenin, and p120CAS is essential for its stabilization and regulation....

usually composed of α-, β-, and γ-catenins, bind to the cytoplasmic portion of the cadherin. Regulatory proteins include p-120 catenin, α {\displaystyle \alpha...

nomenclature is the gap junction protein system, where connexins are sorted by their α (GJA) and β (GJB) forms, with additional connexins grouped into the C, D and...

phosphorylated β-catenin through its interactions with α-catenin. Moreover, loss of Jak3-mediated phosphorylation sites in β-catenin abrogated its AJ...

integral part of the Wnt canonical pathway (β-catenin dependent) and non-canonical pathway (β-catenin-independent). In either of these, DVL acts downstream...

by followers ensures long-range coordination of cell migration through α-catenin mechanoperception". Developmental Cell. 57 (12): 1529–1544.e5. doi:10...

of globular proteins, or one of the member proteins of that superfamily. α- and β-tubulins polymerize into microtubules, a major component of the eukaryotic...

cadherin/ catenin complex in the cytoskeleton. As EpCAM expression increases, the total amount of α-catenin decreases, whereas cellular β-catenin levels...

transitions by regulating the cell adhesion proteins E-cadherin, α-catenin and γ-catenin expression in epithelial cells. Studies have shown that in highly...

Examples of proteins that contain armadillo repeats include β-catenin, Sarm1 (SARM1), α-importin, plakoglobin, adenomatous polyposis coli (APC), and many...

regulation of cell adhesion and actin cytoskeleton via E-cadherin and α-catenin". Proc. Natl. Acad. Sci. U.S.A. 103 (28): 10672–7. Bibcode:2006PNAS..10310672H...

PTPkappa interacts by co-immunoprecipitation with E-cadherin, α-catenin and β-catenin in pancreatic acinar cells prior to the dissolution of adherens...

been suggested that O-GlcNAc plays a role in the interaction of α-catenin and β-catenin. Co-translational O-GlcNAc has been identified on Sp1 and Nup62...

including cancer targets such as p53, MCL-1 BH3, PUMA BH3, Notch, and beta-Catenin, as well as other therapeutic targets ranging from infectious diseases...