• Thumbnail for Γ-Aminobutyric acid
    γ-Aminobutyric acid (gamma-aminobutyric acid) /ˈɡæmə əˈmiːnoʊbjuːˈtɪrɪk ˈæsɪd/, or GABA /ˈɡæbə/, is the chief inhibitory neurotransmitter in the developmentally...
    51 KB (5,563 words) - 23:57, 21 March 2024
  • Cutting G, Uhl GR (April 1992). "gamma-Aminobutyric acid A or C receptor? gamma-Aminobutyric acid rho 1 receptor RNA induces bicuculline-, barbiturate-...
    16 KB (1,639 words) - 05:16, 7 November 2023
  • Thumbnail for Gamma-Hydroxybutyric acid
    acid (or γ-hydroxybutyric acid (GHB), also known as 4-hydroxybutanoic acid) is a naturally occurring neurotransmitter and a depressant drug. It is a precursor...
    80 KB (8,754 words) - 18:02, 9 April 2024
  • Thumbnail for GABA receptor agonist
    and muscle relaxant effects. There are three receptors of the gamma-aminobutyric acid. The two receptors GABA-α and GABA-ρ are ion channels that are permeable...
    8 KB (740 words) - 19:39, 11 March 2024
  • Thumbnail for Gamma-Amino-beta-hydroxybutyric acid
    γ-Amino-β-hydroxybutyric acid (GABOB), also known as β-hydroxy-γ-aminobutyric acid (β-hydroxy-GABA), and sold under the brand name Gamibetal among others...
    8 KB (688 words) - 09:14, 5 December 2023
  • Thumbnail for GABAA receptor
    The GABAA receptor (GABAAR) is an ionotropic receptor and ligand-gated ion channel. Its endogenous ligand is γ-aminobutyric acid (GABA), the major inhibitory...
    54 KB (5,992 words) - 15:58, 28 March 2024
  • Thumbnail for Phenibut
    neurotransmitter γ-aminobutyric acid (GABA), and hence is a GABA analogue. Phenibut is thought to act as a GABAB receptor agonist, similarly to baclofen and γ-hydroxybutyrate...
    31 KB (2,541 words) - 22:24, 17 April 2024
  • (April 2002). "Tranexamic Acid, a Widely Used Antifibrinolytic Agent, Causes Convulsions by a γ-Aminobutyric AcidA Receptor Antagonistic Effect". Journal...
    3 KB (315 words) - 21:55, 14 April 2024
  • Thumbnail for Gamma-Hydroxyvaleric acid
    γ-Hydroxyvaleric acid (GHV), also known as 4-methyl-GHB, is a designer drug related to γ-hydroxybutyric acid (GHB). It is sometimes seen on the grey market...
    3 KB (234 words) - 21:19, 10 March 2024
  • Thumbnail for Gamma-Butyrolactone
    Gamma-butyrolactone (GBL) or γ-butyrolactone is a hygroscopic, colorless, water-miscible liquid with a weak, characteristic odor. It is the simplest 4-carbon...
    29 KB (2,914 words) - 01:31, 27 March 2024
  • Thumbnail for GABA analogue
    GABA analogue (category GABA receptor agonists)
    A GABA analogue is a compound which is an analogue or derivative of the neurotransmitter gamma-Aminobutyric acid (GABA) (the IUPAC of which is 4-aminobutanoic...
    8 KB (754 words) - 04:40, 27 January 2024
  • Thumbnail for Γ-Valerolactone
    and is a potential fuel and green solvent. GVL behaves as a prodrug to γ-hydroxyvaleric acid (GHV), a drug with similar effects to those of γ-hydroxybutyric...
    12 KB (1,075 words) - 04:41, 4 December 2023
  • Thumbnail for Muscimol
    Muscimol (redirect from Ibonetic acid)
    (rho-like) gamma-aminobutyric acid receptors expressed in Xenopus oocytes. II. Pharmacology of gamma-aminobutyric acidA and gamma-aminobutyric acidB receptor...
    26 KB (2,462 words) - 12:17, 23 March 2024
  • Thumbnail for Progabide
    Progabide (category GABAA-rho receptor agonists)
    trade name Gabrene, Sanofi-Aventis) is an analogue and prodrug of γ-aminobutyric acid (GABA) used in the treatment of epilepsy. Via conversion into GABA...
    6 KB (506 words) - 01:37, 4 February 2024
  • neurotransmitter γ-aminobutyric acid (GABA). They are closely related and similar to GABAA receptor antagonists. The effects of GABAA receptor NAMs are functionally...
    10 KB (934 words) - 07:32, 16 September 2023
  • Thumbnail for Picamilon
    Picamilon (category GABAA-rho receptor agonists)
    N-nicotinoyl-GABA, pycamilon, and pikamilon) is a drug formed by a synthetic combination of niacin and γ-aminobutyric acid (GABA). It was developed in the Soviet...
    9 KB (776 words) - 08:59, 3 December 2023
  • Ionotropic GABA receptors (iGABARs) are ligand-gated ion channel of the GABA receptors class which are activated by gamma-aminobutyric acid (GABA), and include:...
    7 KB (687 words) - 19:31, 11 February 2023
  • Thumbnail for 4-Fluorophenibut
    4-Fluorophenibut (category GABAB receptor agonists)
    β-(4-fluorophenyl)-γ-aminobutyric acid or β-(4-fluorophenyl)-GABA) is a GABAB receptor agonist which was never marketed. It is selective for the GABAB receptor over...
    3 KB (181 words) - 20:18, 8 April 2024
  • Thumbnail for GABA receptor
    The GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA), the chief inhibitory compound in the...
    35 KB (3,884 words) - 20:11, 11 February 2024
  • Thumbnail for Hopantenic acid
    pantothenic acid. While pantothenic acid is the amide of D-pantoate and β-alanine, hopantenic acid is the amide of D-pantoate and γ-aminobutyric acid (GABA)...
    3 KB (133 words) - 16:21, 18 September 2023
  • Thumbnail for Ibotenic acid
    acts as a non-selective glutamate receptor agonist. Because of this, ibotenic acid can be a powerful neurotoxin in high doses, and is employed as a "brain-lesioning...
    16 KB (1,473 words) - 07:42, 26 February 2024
  • Thumbnail for Aceburic acid
    4-hydroxybutanoic acid), and based on its structural relation to GHB, is likely to behave as a prodrug to it. 1,4-Butanediol (1,4-BD) 1,6-Dioxecane-2,7-dione γ-Butyrolactone...
    3 KB (141 words) - 09:29, 18 September 2023
  • Thumbnail for Flumazenil
    Flumazenil (category GABAA receptor negative allosteric modulators)
    the human gamma-aminobutyric acid type A receptor alpha 6 subunit and characterization of the pharmacology of alpha 6-containing receptors". Molecular Pharmacology...
    23 KB (2,416 words) - 16:54, 24 March 2024
  • gamma-aminobutyric acid (GABA). For example, a synapse is GABAergic if it uses GABA as its neurotransmitter, and a GABAergic neuron produces GABA. A substance...
    2 KB (139 words) - 10:42, 29 October 2023
  • Thumbnail for GABRA2
    Gamma-aminobutyric acid receptor subunit alpha-2 is a protein in humans that is encoded by the GABRA2 gene. GABRA2 is an alpha subunit that is part of...
    15 KB (1,827 words) - 12:10, 4 April 2024
  • Thumbnail for Oenanthotoxin
    Oenanthotoxin (category GABAA receptor negative allosteric modulators)
    nervous system poison, and acts as a noncompetitive antagonist of the neurotransmitter gamma-aminobutyric acid. A case has been made for the presence...
    11 KB (999 words) - 15:41, 13 April 2024
  • Thumbnail for Cicutoxin
    Cicutoxin (category GABAA receptor negative allosteric modulators)
    the central nervous system. It is a potent, noncompetitive antagonist of the gamma-aminobutyric acid (GABA) receptor. In humans, cicutoxin rapidly produces...
    28 KB (2,937 words) - 10:01, 18 August 2023
  • Thumbnail for Gamma-aminobutyric acid receptor subunit alpha-1
    Gamma-aminobutyric acid receptor subunit alpha-1 is a protein that in humans is encoded by the GABRA1 gene. GABA is the major inhibitory neurotransmitter...
    8 KB (1,048 words) - 22:35, 22 December 2023
  • Thumbnail for Tolibut
    Tolibut (category Gamma-Amino acids)
    3-(p-tolyl)-4-aminobutyric acid (or β-(4-methylphenyl)-GABA), is drug that was developed in Russia. It is an analogue of γ-aminobutyric acid (GABA) and is...
    4 KB (247 words) - 16:13, 21 March 2024
  • Isonipecotic acid is a heterocyclic compound which acts as a GABAA receptor partial agonist. It consists of a piperidine ring with a carboxylic acid moiety...
    2 KB (90 words) - 20:07, 27 December 2022