• In enzymology, a 1-methyladenosine nucleosidase (EC 3.2.2.13) is an enzyme that catalyzes the chemical reaction 1-methyladenosine + H2O ⇌ {\displaystyle...
    1 KB (117 words) - 12:23, 26 August 2023
  • Thumbnail for N6-Methyladenosine
    N6-Methyladenosine (m6A) was originally identified and partially characterised in the 1970s, and is an abundant modification in mRNA and DNA. It is found...
    52 KB (5,572 words) - 01:58, 8 April 2024
  • most common and well-understood mRNA modification at present is N6-Methyladenosine (m6A), which has been observed to occur an average of three times in...
    62 KB (7,732 words) - 05:51, 25 April 2024
  • Thumbnail for Tears
    carboxy- methyl cellulose or hemi-cellulose in strengths of either 0.5% or 1% depending upon the severity of drying up of the cornea.[citation needed]...
    23 KB (1,896 words) - 11:57, 4 January 2024
  • β-aspartyl-N-acetylglucosaminidase EC 3.2.2.12: inosinate nucleosidase EC 3.2.2.13: 1-methyladenosine nucleosidase EC 3.2.2.14: NMN nucleosidase EC 3.2.2.15: DNA-deoxyinosine...
    119 KB (15,553 words) - 03:35, 27 April 2024
  • In enzymology, a mRNA (2'-O-methyladenosine-N6-)-methyltransferase (EC 2.1.1.62) is an enzyme that catalyzes the chemical reaction S-adenosyl-L-methionine...
    2 KB (174 words) - 15:00, 26 August 2023
  • (October 2010). "New archaeal methyltransferases forming 1-methyladenosine or 1-methyladenosine and 1-methylguanosine at position 9 of tRNA". Nucleic Acids...
    2 KB (180 words) - 16:07, 26 August 2023
  • P Xie, E He, B Shen#, C He#. YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs. elife 2017,6, e31311 H Shi*, X Wang*, Z Lu, B S Zhao...
    6 KB (594 words) - 22:35, 22 January 2024
  • PMID 27572442. Tirumuru, Nagaraja; Wu, Li (March 2019). "HIV-1 envelope proteins up-regulate N6-methyladenosine levels of cellular RNA independently of viral replication"...
    13 KB (1,527 words) - 14:26, 7 May 2024
  • Thumbnail for Chuan He
    discovered the first RNA demethylase that oxidatively reverses N6-methyladenosine (m6A) methylation in mammalian messenger RNA (mRNA) in 2011. The existence...
    12 KB (1,145 words) - 06:22, 16 February 2024
  • 2000). "The Gcd10p/Gcd14p complex is the essential two-subunit tRNA(1-methyladenosine) methyltransferase of Saccharomyces cerevisiae". Proceedings of the...
    2 KB (231 words) - 16:06, 26 August 2023
  • (October 2010). "New archaeal methyltransferases forming 1-methyladenosine or 1-methyladenosine and 1-methylguanosine at position 9 of tRNA". Nucleic Acids...
    2 KB (139 words) - 16:06, 26 August 2023
  • Thumbnail for Theacrine
    Theacrine (redirect from 2309-49-1)
    locomotor activity in rats". Pharmacology, Biochemistry, and Behavior. 47 (1): 89–94. doi:10.1016/0091-3057(94)90115-5. ISSN 0091-3057. PMID 7906891. S2CID 23508010...
    6 KB (547 words) - 21:35, 5 April 2024
  • Thumbnail for Epitranscriptomic sequencing
    major classes of chemical modifications found in RNA molecules: N6-methyladenosine, 2'-O-methylation, N6,2'-O-dimethyladenosine, 5-methylcytidine,...
    51 KB (6,385 words) - 15:50, 26 April 2024
  • Thumbnail for Phenolphthalein
    were found to be 9.05, 9.50 and 12 while those of phenolsulfonphthalein are 1.2 and 7.70. Phenolphthalein's pH sensitivity is exploited in other applications:...
    20 KB (1,809 words) - 12:54, 22 December 2023
  • Thumbnail for Purine
    bonded to a different one of the four nitrogen atoms. These are identified as 1-H, 3-H, 7-H, and 9-H (see image of numbered ring). The common crystalline...
    24 KB (2,510 words) - 13:01, 6 February 2024
  • 1.1.43: Now described by EC 2.1.1.354, EC 2.1.1.355, EC 2.1.1.356, EC 2.1.1.357, EC 2.1.1.358, EC 2.1.1.359, EC 2.1.1.360, EC 2.1.1.361 and EC 2.1.1.362...
    215 KB (21,664 words) - 23:41, 8 May 2024
  • Thumbnail for Caffeine
    History of the Behavioral Sciences. 27 (1): 42–55. doi:10.1002/1520-6696(199101)27:1<42::AID-JHBS2300270105>3.0.CO;2-1. PMID 2010614. "The Rise and Fall of...
    199 KB (19,813 words) - 06:55, 7 May 2024
  • before DNA methylation in the early forms of life evolving on earth. N6-methyladenosine (m6A) is the most common and abundant methylation modification in RNA...
    28 KB (3,051 words) - 02:03, 23 April 2024
  • Thumbnail for Guanosine triphosphate
    phosphates on their ribose sugar. GTP has the guanine nucleobase attached to the 1' carbon of the ribose and it has the triphosphate moiety attached to ribose's...
    8 KB (607 words) - 16:16, 2 May 2023
  • Thumbnail for Nucleoside
    broken down inside the cell into nitrogenous bases, and ribose-1-phosphate or deoxyribose-1-phosphate. In medicine several nucleoside analogues are used...
    10 KB (851 words) - 01:58, 1 December 2023
  • Thumbnail for Pentoxifylline
    com drugs.com international listings for Pentoxifylline. Page accessed Feb 1, 206 "PRODUCT INFORMATION TRENTAL® 400" (PDF). TGA eBusiness Services. sanofi-aventis...
    19 KB (1,801 words) - 07:08, 22 April 2024
  • Thumbnail for YTHDF2
    YTHDF2 (category Genes on human chromosome 1)
    YTH N6-methyladenosine RNA binding protein 2 is a protein that in humans is encoded by the YTHDF2 gene. This gene encodes a member of the YTH (YT521-B...
    4 KB (672 words) - 00:04, 30 November 2023
  • Thumbnail for Epigenetics
    even cytoplasmic (structural) heritable states. RNA methylation of N6-methyladenosine (m6A) as the most abundant eukaryotic RNA modification has recently...
    161 KB (18,430 words) - 14:05, 5 May 2024
  • Thumbnail for Theophylline
    absorbs maximally at 277 nm with an extinction coefficient of 10,200 (cm−1 M−1). The characteristic signals, distinguishing theophylline from related methylxanthines...
    24 KB (2,233 words) - 16:40, 28 April 2024
  • Thumbnail for Adenosine diphosphate
    to the 5’ carbon of the sugar backbone, while the adenine attaches to the 1’ carbon. ADP can be interconverted to adenosine triphosphate (ATP) and adenosine...
    14 KB (1,299 words) - 01:54, 25 September 2023
  • Thumbnail for Rhein (molecule)
    protein, an enzyme responsible for removing the methylation from N6-methyladenosine in nucleic acids. The pharmacokinetics of rhein have not been intensively...
    7 KB (631 words) - 22:31, 9 August 2023
  • Thumbnail for Alcohol (drug)
    Alcohol (drug) (category IARC Group 1 carcinogens)
    fetal alcohol syndrome". Obstetrics and Gynecology. 106 (5 Pt 1): 1059–1064. CiteSeerX 10.1.1.537.7292. doi:10.1097/01.AOG.0000181822.91205.6f. PMID 16260526...
    209 KB (21,044 words) - 07:40, 10 May 2024
  • Thumbnail for DMPX
    DMPX (3,7-dimethyl-1-propargylxanthine) is a caffeine analog which displays affinity to A2 adenosine receptors, in contrast to the A1 subtype receptors...
    2 KB (104 words) - 16:44, 24 January 2023
  • it can be further methylated at the N6 methyl position to form N6-methyladenosine, resulting in 5′(m7Gp)(ppm6Am)[pN]n. The mechanism of capping with...
    16 KB (1,873 words) - 09:28, 17 November 2023