pregn-4-ene-3,11,20-trione 11β-Hydroxypregnenolone = 3β,11β-dihydroxypregn-5-en-20-one [1] 11β-Hydroxyprogesterone (21-deoxycorticosterone) = 11β-hydroxypregn-4-ene-3...
11 KB (1,237 words) - 00:17, 3 December 2023
17α-Hydroxypregnenolone is a pregnane (C21) steroid that is obtained by hydroxylation of pregnenolone at the C17α position. This step is performed by...
5 KB (360 words) - 19:10, 8 March 2023
synthase (for aldosterone) or by the 11β-hydroxylase (for corticosterone). These enzymes are nearly identical (they share 11β-hydroxylation and 18-hydroxylation...
32 KB (3,377 words) - 13:20, 24 January 2024
steroid cortisol by stereospecific hydrogenation at carbon 11 by the enzyme 11β-Hydroxysteroid dehydrogenase type 1, particularly in the liver. The term...
16 KB (1,516 words) - 10:47, 15 August 2024
21-Hydroxypregnenolone, also known as prebediolone, as well as 3β,21-dihydroxypregn-5-en-20-one, is a naturally occurring and endogenous pregnane steroid...
3 KB (243 words) - 16:26, 26 April 2023
22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone 21-Hydroxypregnenolone 17α,21-Dihydroxypregnenolone 11β,17α,21-Trihydroxypregnenolone...
29 KB (3,167 words) - 17:10, 11 September 2024
Pregnenolone → Progesterone → Allopregnanedione → Allopregnanolone 17α-Hydroxypregnenolone → 17α-Hydroxyprogesterone Androgens Dehydroepiandrosterone → Androstenedione...
7 KB (617 words) - 11:09, 2 September 2024
11β-Hydroxytestosterone is an endogenous steroid, a metabolite of testosterone. Although it may not have significant androgenic activity, it may still...
3 KB (223 words) - 23:51, 31 December 2023
synthase (for aldosterone) or by the 11β-hydroxylase (for corticosterone). These enzymes are nearly identical (they share 11β-hydroxylation and 18-hydroxylation...
41 KB (4,147 words) - 01:54, 20 July 2024
TrkA and p75NTR agonist Anicequol (NGA0187, NGD-187): 16β-acetoxy-3β,7β,11β-trihydroxy-5α-ergost-22(E)-en-6-one – non-endogenous; fungi-derived; undefined...
19 KB (2,007 words) - 23:03, 8 December 2023
11β-Hydroxyprogesterone (11β-OHP), also known as 21-deoxycorticosterone, as well as 11β-hydroxypregn-4-ene-3,20-dione, is a naturally occurring, endogenous...
14 KB (1,490 words) - 00:15, 11 April 2024
which designates unsaturation, for example, 4-pregnene-11β,17α-diol-3,20-dione (also Δ4-pregnene-11β,17α-diol-3,20-dione) or 4-androstene-3,11,17-trione...
83 KB (8,473 words) - 21:34, 16 September 2024
one of two ways. The primary pathway involves conversion of 17α-hydroxypregnenolone to DHEA by way of 17,20-lyase, with subsequent conversion of DHEA...
19 KB (1,899 words) - 15:35, 24 January 2024
22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone 21-Hydroxypregnenolone 17α,21-Dihydroxypregnenolone 11β,17α,21-Trihydroxypregnenolone...
37 KB (3,971 words) - 05:07, 16 August 2024
22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone 21-Hydroxypregnenolone 17α,21-Dihydroxypregnenolone 11β,17α,21-Trihydroxypregnenolone...
15 KB (1,674 words) - 08:45, 22 August 2024
Corticosterone (redirect from 11β,21-Dihydroprogesterone)
Corticosterone, also known as 17-deoxycortisol and 11β,21-dihydroxyprogesterone, is a 21-carbon steroid hormone of the corticosteroid type produced in...
12 KB (1,207 words) - 15:29, 27 June 2024
is prevented by rapid degradation of cortisol by 11β-hydroxysteroid dehydrogenase isoenzyme 2 (11β-HSD2) in mineralocorticoid target tissues. Mineralocorticoid...
53 KB (5,544 words) - 20:09, 28 July 2024
Cortisol is a naturally occurring pregnane corticosteroid and is also known as 11β,17α,21-trihydroxypregn-4-ene-3,20-dione. In animals, cortisol is often used...
78 KB (8,594 words) - 07:41, 12 September 2024
progesterone or its derivatives. Pregnenolone can be converted to 17α-hydroxypregnenolone by the enzyme 17α-hydroxylase (CYP17A1). Using this pathway, termed...
21 KB (2,059 words) - 07:45, 3 June 2024
22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone 21-Hydroxypregnenolone 17α,21-Dihydroxypregnenolone 11β,17α,21-Trihydroxypregnenolone...
41 KB (4,347 words) - 19:57, 8 August 2024
17α-hydroxyprogesterone. These progestogens, along with another steroid, 17α-hydroxypregnenolone, are the precursors of all other endogenous steroids, including the...
16 KB (1,567 words) - 13:48, 19 June 2024
22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone 21-Hydroxypregnenolone 17α,21-Dihydroxypregnenolone 11β,17α,21-Trihydroxypregnenolone...
67 KB (6,821 words) - 20:22, 2 August 2024
metabolism. In addition to 6β- and 16β-hydroxytestosterone, 1β-, 2α/β-, 11β-, and 15β-hydroxytestosterone are also formed as minor metabolites. Certain...
149 KB (15,717 words) - 14:45, 15 September 2024
22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone 21-Hydroxypregnenolone 17α,21-Dihydroxypregnenolone 11β,17α,21-Trihydroxypregnenolone...
75 KB (7,245 words) - 18:06, 26 August 2024
proteins via indirect, genomic mechanisms, including the enzymes CYP2C11 and 11β-HSD1 – the latter of which is essential for the biosynthesis of the glucocorticoids...
42 KB (3,935 words) - 04:01, 30 April 2024
hyperplasia as the typical enzymes that are defective, namely 21-hydroxylase and 11β-hydroxylase, lead to a build-up of 17α-OHP. In contrast, the rare patient...
14 KB (1,126 words) - 10:08, 7 July 2024
22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone 21-Hydroxypregnenolone 17α,21-Dihydroxypregnenolone 11β,17α,21-Trihydroxypregnenolone...
7 KB (723 words) - 17:59, 15 May 2024
21-Deoxycortisol (redirect from 11β,17α-dihydroxyprogesterone)
as 11β,17α-dihydroxyprogesterone or as 11β,17α-dihydroxypregn-4-ene-3,20-dione, is a naturally occurring, endogenous steroid related to cortisol (11β,17α...
14 KB (1,448 words) - 18:29, 20 February 2024
11β-Hydroxyandrostenedione (11β-OHA4), also known as 11β-hydroxyandrost-4-ene-3,17-dione, is an endogenous, naturally occurring steroid and androgen prohormone...
3 KB (195 words) - 22:38, 31 January 2024
mutations in genes affecting other enzymes involved in steroid metabolism, like 11β-hydroxylase or 3β-hydroxysteroid dehydrogenase. It has a prevalence between...
43 KB (4,688 words) - 16:42, 1 August 2024