• Thumbnail for 21-Hydroxypregnenolone
    21-Hydroxypregnenolone, also known as prebediolone, as well as 3β,21-dihydroxypregn-5-en-20-one, is a naturally occurring and endogenous pregnane steroid...
    3 KB (243 words) - 16:26, 26 April 2023
  • Thumbnail for 17α-Hydroxypregnenolone
    17α-Hydroxypregnenolone is a pregnane (C21) steroid that is obtained by hydroxylation of pregnenolone at the C17α position. This step is performed by...
    5 KB (360 words) - 19:10, 8 March 2023
  • Thumbnail for Androgen
    22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone 21-Hydroxypregnenolone 17α,21-Dihydroxypregnenolone 11β,17α,21-Trihydroxypregnenolone...
    29 KB (3,165 words) - 22:29, 23 March 2024
  • Thumbnail for List of corticosteroids
    pregn-4-ene-3,11,20-trione 11β-Hydroxypregnenolone = 3β,11β-dihydroxypregn-5-en-20-one [1] 11β-Hydroxyprogesterone (21-deoxycorticosterone) = 11β-hydroxypregn-4-ene-3...
    11 KB (1,237 words) - 00:17, 3 December 2023
  • Thumbnail for Aldosterone
    synthase (for aldosterone) or by the 11β-hydroxylase (for corticosterone). These enzymes are nearly identical (they share 11β-hydroxylation and 18-hydroxylation...
    32 KB (3,377 words) - 13:20, 24 January 2024
  • Thumbnail for Cortisone
    steroid cortisol by stereospecific hydrogenation at carbon 11 by the enzyme 11β-Hydroxysteroid dehydrogenase type 1, particularly in the liver. The term...
    16 KB (1,509 words) - 14:16, 24 December 2023
  • Thumbnail for Sex hormone
    Pregnenolone → Progesterone → Allopregnanedione → Allopregnanolone 17α-Hydroxypregnenolone → 17α-Hydroxyprogesterone Androgens Dehydroepiandrosterone → Androstenedione...
    7 KB (587 words) - 01:59, 24 November 2023
  • Thumbnail for List of neurosteroids
    TrkA and p75NTR agonist Anicequol (NGA0187, NGD-187): 16β-acetoxy-3β,7β,11β-trihydroxy-5α-ergost-22(E)-en-6-one – non-endogenous; fungi-derived; undefined...
    19 KB (2,007 words) - 23:03, 8 December 2023
  • Thumbnail for 11β-Hydroxyprogesterone
    11β-Hydroxyprogesterone (11β-OHP), also known as 21-deoxycorticosterone, as well as 11β-hydroxypregn-4-ene-3,20-dione, is a naturally occurring, endogenous...
    14 KB (1,490 words) - 00:15, 11 April 2024
  • Thumbnail for Steroid
    which designates unsaturation, for example, 4-pregnene-11β,17α-diol-3,20-dione (also Δ4-pregnene-11β,17α-diol-3,20-dione) or 4-androstene-3,11,17-trione...
    81 KB (8,331 words) - 12:04, 6 May 2024
  • Thumbnail for Corticosterone
    Corticosterone, also known as 17-deoxycortisol and 11β,21-dihydroxyprogesterone, is a 21-carbon steroid hormone of the corticosteroid type produced in...
    12 KB (1,193 words) - 15:46, 10 December 2023
  • Thumbnail for Cortisol
    Cortisol is a naturally occurring pregnane corticosteroid and is also known as 11β,17α,21-trihydroxypregn-4-ene-3,20-dione. In animals, cortisol is often used...
    77 KB (8,516 words) - 23:51, 30 April 2024
  • Thumbnail for Corticosteroid
    synthase (for aldosterone) or by the 11β-hydroxylase (for corticosterone). These enzymes are nearly identical (they share 11β-hydroxylation and 18-hydroxylation...
    41 KB (4,133 words) - 04:03, 1 May 2024
  • Thumbnail for Steroid hormone
    22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone 21-Hydroxypregnenolone 17α,21-Dihydroxypregnenolone 11β,17α,21-Trihydroxypregnenolone...
    15 KB (1,674 words) - 02:59, 22 February 2024
  • Thumbnail for 11β-Hydroxytestosterone
    11β-Hydroxytestosterone is an endogenous steroid, a metabolite of testosterone. Although it may not have significant androgenic activity, it may still...
    3 KB (223 words) - 23:51, 31 December 2023
  • Thumbnail for Mineralocorticoid
    22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone 21-Hydroxypregnenolone 17α,21-Dihydroxypregnenolone 11β,17α,21-Trihydroxypregnenolone...
    7 KB (723 words) - 11:52, 5 January 2024
  • Thumbnail for Estrone
    22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone 21-Hydroxypregnenolone 17α,21-Dihydroxypregnenolone 11β,17α,21-Trihydroxypregnenolone...
    38 KB (3,994 words) - 08:40, 10 March 2024
  • Thumbnail for Androstenedione
    one of two ways. The primary pathway involves conversion of 17α-hydroxypregnenolone to DHEA by way of 17,20-lyase, with subsequent conversion of DHEA...
    19 KB (1,899 words) - 15:35, 24 January 2024
  • Thumbnail for 21-Deoxycortisol
    as 11β,17α-dihydroxyprogesterone or as 11β,17α-dihydroxypregn-4-ene-3,20-dione, is a naturally occurring, endogenous steroid related to cortisol (11β,17α...
    14 KB (1,448 words) - 18:29, 20 February 2024
  • Thumbnail for Pregnenolone
    progesterone or its derivatives. Pregnenolone can be converted to 17α-hydroxypregnenolone by the enzyme 17α-hydroxylase (CYP17A1). Using this pathway, termed...
    21 KB (2,059 words) - 19:15, 7 December 2023
  • Thumbnail for Progestogen
    17α-hydroxyprogesterone. These progestogens, along with another steroid, 17α-hydroxypregnenolone, are the precursors of all other endogenous steroids, including the...
    16 KB (1,566 words) - 09:04, 13 December 2023
  • Thumbnail for Neurosteroid
    22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone 21-Hydroxypregnenolone 17α,21-Dihydroxypregnenolone 11β,17α,21-Trihydroxypregnenolone...
    41 KB (4,347 words) - 18:35, 7 April 2024
  • Thumbnail for Testosterone
    metabolism. In addition to 6β- and 16β-hydroxytestosterone, 1β-, 2α/β-, 11β-, and 15β-hydroxytestosterone are also formed as minor metabolites. Certain...
    149 KB (15,672 words) - 19:15, 8 May 2024
  • Thumbnail for Dihydrotestosterone
    22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone 21-Hydroxypregnenolone 17α,21-Dihydroxypregnenolone 11β,17α,21-Trihydroxypregnenolone...
    67 KB (6,821 words) - 14:50, 18 March 2024
  • Thumbnail for Glucocorticoid
    is prevented by rapid degradation of cortisol by 11β-hydroxysteroid dehydrogenase isoenzyme 2 (11β-HSD2) in mineralocorticoid target tissues. Mineralocorticoid...
    53 KB (5,521 words) - 14:48, 29 April 2024
  • Thumbnail for 11β-Hydroxyandrostenedione
    11β-Hydroxyandrostenedione (11β-OHA4), also known as 11β-hydroxyandrost-4-ene-3,17-dione, is an endogenous, naturally occurring steroid and androgen prohormone...
    3 KB (195 words) - 22:38, 31 January 2024
  • Thumbnail for Estradiol
    22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone 21-Hydroxypregnenolone 17α,21-Dihydroxypregnenolone 11β,17α,21-Trihydroxypregnenolone...
    72 KB (7,059 words) - 20:31, 8 March 2024
  • mutations in genes affecting other enzymes involved in steroid metabolism, like 11β-hydroxylase or 3β-hydroxysteroid dehydrogenase. It has a prevalence between...
    43 KB (4,673 words) - 17:06, 28 March 2024
  • Thumbnail for 17α-Hydroxyprogesterone
    hyperplasia as the typical enzymes that are defective, namely 21-hydroxylase and 11β-hydroxylase, lead to a build-up of 17α-OHP. In contrast, the rare patient...
    13 KB (1,059 words) - 09:02, 24 January 2024
  • Thumbnail for Dehydroepiandrosterone
    proteins via indirect, genomic mechanisms, including the enzymes CYP2C11 and 11β-HSD1 – the latter of which is essential for the biosynthesis of the glucocorticoids...
    42 KB (3,935 words) - 04:01, 30 April 2024