 | 11β-Hydroxysteroid dehydrogenase type 1, also known as cortisone reductase, is an NADPH-dependent enzyme highly expressed in key metabolic tissues including... 11 KB (1,336 words) - 00:18, 1 February 2024 |
11β-Hydroxysteroid dehydrogenase (HSD-11β or 11β-HSD) enzymes catalyze the conversion of inert 11 keto-products (cortisone) to active cortisol, or vice... 17 KB (1,900 words) - 21:43, 18 March 2024 |
 | stereospecific hydrogenation at carbon 11 by the enzyme 11β-Hydroxysteroid dehydrogenase type 1, particularly in the liver. The term "cortisone" is frequently... 16 KB (1,509 words) - 14:16, 24 December 2023 |
 | are four types, classified by the number of the position acted upon: Steroidogenic enzyme Steroid hydroxylase Hydroxysteroid+Dehydrogenases at the U.S... 2 KB (60 words) - 16:44, 31 December 2023 |
 | Corticosteroid 11-β-dehydrogenase isozyme 2 also known as 11-β-hydroxysteroid dehydrogenase 2 is an enzyme that in humans is encoded by the HSD11B2 gene... 11 KB (1,085 words) - 19:55, 22 September 2023 |
 | Apparent mineralocorticoid excess syndrome (redirect from 11 beta hydroxysteroid dehydrogenase type 2 deficiency) in the HSD11B2 gene, which encodes the kidney isozyme of 11β-hydroxysteroid dehydrogenase type 2. In an unaffected individual, this isozyme inactivates... 12 KB (1,131 words) - 13:21, 9 March 2024 |
 | reductase deficiency is caused by dysregulation of the 11β-hydroxysteroid dehydrogenase type 1 enzyme (11β-HSD1), otherwise known as cortisone reductase, a... 15 KB (1,506 words) - 17:59, 9 April 2023 |
 | to 4'-hydroxybupropion. The reductive pathways are by 11β-hydroxysteroid dehydrogenase type 1 in the liver and AKR7A2/AKR7A3 in the intestine leading... 111 KB (10,324 words) - 05:21, 29 April 2024 |
 | subsequently claimed by AstraZeneca as an inhibitor of the enzyme 11β-Hydroxysteroid dehydrogenase type 1. No other pharmacological data has been disclosed, though... 2 KB (153 words) - 20:35, 30 March 2024 |
 | Cortisol (section 11beta-hydroxysteroid dehydrogenases) "Expression and activity of the cortisol-activating enzyme 11β-hydroxysteroid dehydrogenase type 1 is tissue and species-specific". Chemico-Biological Interactions... 77 KB (8,516 words) - 17:35, 29 April 2024 |
 | 5α-Reductase (redirect from 3-oxo-5a-steroid 4-dehydrogenase) cortisol through the liver via 5α-reductase and kidneys via 11β-hydroxysteroid dehydrogenase type 2, longterm elevation of cortisol can lead to Cushing's... 37 KB (4,015 words) - 10:10, 11 April 2024 |
 | Carbenoxolone (category 11β-Hydroxysteroid dehydrogenase inhibitors) conversion of inactive cortisone to cortisol by blocking 11β-hydroxysteroid dehydrogenase (11β-HSD). 11β-HSD also reversibly catalyzes the conversion of 7-ketocholesterol... 5 KB (342 words) - 00:22, 1 March 2023 |
 | Congenital adrenal hyperplasia (redirect from Congenital adrenal hyperplasia type 1) in an apparent vulva. Ambiguous genitalia in XY males with 3β-hydroxysteroid dehydrogenase deficiency (3β-HSD2D). In females, hypogonadism can cause sexual... 43 KB (4,403 words) - 15:41, 30 March 2024 |
 | Fluoxymesterone (category 11β-Hydroxysteroid dehydrogenase inhibitors) Fluoxymesterone has been found to act as a potent inhibitor of 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) (IC50Tooltip Half-maximal inhibitory concentration... 27 KB (2,325 words) - 08:10, 2 February 2024 |
 | (February 2024). "The glucocorticoid-activating enzyme 11β-hydroxysteroid dehydrogenase type 1 catalyzes the activation of testosterone". J Steroid Biochem... 81 KB (8,329 words) - 02:06, 22 April 2024 |
involved in steroid metabolism, like 11β-hydroxylase or 3β-hydroxysteroid dehydrogenase. It has a prevalence between 0.1% and 2% depending on population,... 43 KB (4,673 words) - 17:06, 28 March 2024 |
 | 11α-Hydroxyprogesterone (category 11β-Hydroxysteroid dehydrogenase inhibitors) epimer 11β-hydroxyprogesterone, was identified as a very potent competitive inhibitor of both isoforms (1 and 2) of 11β-hydroxysteroid dehydrogenase (11β-HSD)... 10 KB (848 words) - 01:10, 23 July 2023 |
17)β-hydroxysteroid dehydrogenase EC 1.1.1.52: 3α-hydroxycholanate dehydrogenase (NAD+) EC 1.1.1.53: 3α(or 20β)-hydroxysteroid dehydrogenase EC 1.1.1.54: allyl-alcohol... 189 KB (24,607 words) - 23:55, 9 February 2024 |
 | Enoxolone (category 11β-Hydroxysteroid dehydrogenase inhibitors) in the kidneys. This occurs via inhibition of the enzyme 11-β-hydroxysteroid dehydrogenase.[citation needed] As a result, cortisol levels become high within... 12 KB (1,013 words) - 00:47, 27 April 2024 |
Prostaglandin F synthase (redirect from EC 1.1.1.188) is categorized as C3 (AKR1C3) because it is an isoform of 3α-hydroxysteroid dehydrogenase. The function of PGFS is to catalyze the reduction of aldehydes... 12 KB (1,352 words) - 18:44, 24 April 2024 |
 | Inborn errors of steroid metabolism (section Types) blocks production of all steroid hormones from cholesterol 3β-Hydroxysteroid dehydrogenase 2 deficiency: impairs progestogen and androgen metabolism; prevents... 9 KB (720 words) - 22:08, 23 April 2024 |
 | by 3β-hydroxysteroid dehydrogenase type I into androstenedione, and androstenedione is aromatized into estrone. Then, placental 17β-hydroxysteroid dehydrogenase... 22 KB (2,085 words) - 20:44, 16 March 2024 |
Secondary hypertension (section Types) hypertension. 11β-hydroxylase deficiency, aka apparent mineralocorticoid excess syndrome, involves a defect in the gene for 11β-hydroxysteroid dehydrogenase, an... 35 KB (3,635 words) - 05:59, 25 March 2024 |
 | Progesterone (category 11β-Hydroxysteroid dehydrogenase inhibitors) further reduction of these metabolites via 3α-hydroxysteroid dehydrogenase and 3β-hydroxysteroid dehydrogenase into the tetrahydrogenated allopregnanolone... 123 KB (11,590 words) - 02:03, 21 April 2024 |
 | overstimulation by glucocorticoids. This enzyme, 11-beta hydroxysteroid dehydrogenase type II (Protein:HSD11B2), catalyzes the deactivation of glucocorticoids... 7 KB (723 words) - 11:52, 5 January 2024 |
 | 3α-hydroxysteroid dehydrogenase (3α-HSD), i.e. by the two aldo-keto reductase isozymes: AKR1C2 and AKR1C4, and by 17β-hydroxysteroid dehydrogenase 6 (HSD17B6)... 14 KB (1,217 words) - 02:44, 8 March 2024 |
 | and inhibitors for the human 11beta-hydroxysteroid dehydrogenase type 1". J. Steroid Biochem. Mol. Biol. 105 (1–5): 159–65. doi:10.1016/j.jsbmb.2006... 3 KB (141 words) - 22:53, 27 April 2023 |
steroid hormones by the action of two enzymes, 5α-reductase and 3α-hydroxysteroid dehydrogenase (3α-HSD). These enzymes can be inhibited by 5α-reductase inhibitors... 12 KB (1,256 words) - 18:34, 6 April 2024 |
 | (respectively) similarly) are known to be potent inhibitors of 11β-hydroxysteroid dehydrogenase (11β-HSD), which is responsible for the biosynthesis of the potent... 9 KB (649 words) - 18:08, 26 December 2023 |
 | deoxycorticosterone by the action of two enzymes, 5α-reductase type I and 3α-hydroxysteroid dehydrogenase. THDOC is a potent positive allosteric modulator of the... 6 KB (524 words) - 17:33, 15 July 2022 |