• Thumbnail for 17α-Hydroxyprogesterone
    17α-Hydroxyprogesterone (17α-OHP), also known as 17-OH progesterone (17-OHP), or hydroxyprogesterone (OHP), is an endogenous progestogen steroid hormone...
    13 KB (1,059 words) - 09:02, 24 January 2024
  • Thumbnail for 21-Deoxycortisol
    21-Deoxycortisol, also known as 11β,17α-dihydroxyprogesterone or as 11β,17α-dihydroxypregn-4-ene-3,20-dione, is a naturally occurring, endogenous steroid...
    14 KB (1,448 words) - 18:29, 20 February 2024
  • Thumbnail for Progestogen
    progestogens and are used in medicine. Major examples of progestins include the 17α-hydroxyprogesterone derivative medroxyprogesterone acetate and the 19-nortestosterone...
    16 KB (1,566 words) - 09:04, 13 December 2023
  • Thumbnail for Mineralocorticoid
    Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone 21-Hydroxypregnenolone 17α,21-Dihydroxypregnenolone 11β,17α,21-Trihydroxypregnenolone Corticosteroids...
    7 KB (723 words) - 11:52, 5 January 2024
  • Thumbnail for Sex hormone
    Pregnenolone → Progesterone → Allopregnanedione → Allopregnanolone 17α-Hydroxypregnenolone → 17α-Hydroxyprogesterone Androgens Dehydroepiandrosterone → Androstenedione...
    7 KB (587 words) - 01:59, 24 November 2023
  • Thumbnail for Pregnenolone
    or its derivatives. Pregnenolone can be converted to 17α-hydroxypregnenolone by the enzyme 17α-hydroxylase (CYP17A1). Using this pathway, termed Δ5 pathway...
    21 KB (2,059 words) - 19:15, 7 December 2023
  • Thumbnail for List of corticosteroids
    [2] 17α,21-Dihydroxypregnenolone = 3β,17α,21-trihydroxypregn-5-en-20-one [3] 17α-Hydroxypregnenolone = 3β,17α-dihydroxypregn-5-en-20-one 17α-Hydroxyprogesterone...
    11 KB (1,237 words) - 00:17, 3 December 2023
  • Thumbnail for Steroid hormone
    Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone 21-Hydroxypregnenolone 17α,21-Dihydroxypregnenolone 11β,17α,21-Trihydroxypregnenolone Corticosteroids...
    15 KB (1,674 words) - 02:59, 22 February 2024
  • Thumbnail for 17α-Hydroxypregnenolone
    17α-Hydroxypregnenolone is a pregnane (C21) steroid that is obtained by hydroxylation of pregnenolone at the C17α position. This step is performed by...
    5 KB (360 words) - 19:10, 8 March 2023
  • Thumbnail for Aldosterone
    the mitochondria and require adrenodoxin as a cofactor (except 21-hydroxylase and 17α-hydroxylase). Aldosterone and corticosterone share the first part...
    32 KB (3,377 words) - 13:20, 24 January 2024
  • Thumbnail for Steroid
    congenital adrenal hyperplasia a deficiency in the 21-hydroxylase enzymatic pathway leads to an excess of 17α-Hydroxyprogesterone (17-OHP) – this pathological...
    81 KB (8,329 words) - 02:06, 22 April 2024
  • Thumbnail for 11-Deoxycortisol
    also known as cortodoxone (INN), cortexolone as well as 17α,21-dihydroxyprogesterone or 17α,21-dihydroxypregn-4-ene-3,20-dione, is an endogenous glucocorticoid...
    23 KB (2,316 words) - 02:06, 26 March 2024
  • Thumbnail for List of neurosteroids
    2'-oxiran)-3β-ol – TrkA, TrkB, and p75NTR agonist BNN-27: 17α,20R-epoxypregn-5-ene-3β,21-diol – TrkA and p75NTR agonist Testosterone: androst-4-en-17β-ol-3-one...
    19 KB (2,007 words) - 23:03, 8 December 2023
  • Thumbnail for Androstadienone
    Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone 21-Hydroxypregnenolone 17α,21-Dihydroxypregnenolone 11β,17α,21-Trihydroxypregnenolone Corticosteroids...
    6 KB (442 words) - 10:40, 28 December 2023
  • Thumbnail for Androgen
    Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone 21-Hydroxypregnenolone 17α,21-Dihydroxypregnenolone 11β,17α,21-Trihydroxypregnenolone Corticosteroids...
    29 KB (3,165 words) - 22:29, 23 March 2024
  • Thumbnail for 5α-Pregnane-3α,17α-diol-20-one
    5α-Pregnane-3α,17α-diol-20-one, also known as 17α-hydroxyallopregnanolone (17-OH-allo) is an endogenous steroid. 5α-Pregnane-3α,17α-diol-20-one is a metabolite...
    14 KB (1,217 words) - 02:44, 8 March 2024
  • Thumbnail for Cortisone
    Cortisone is a pregnene (21-carbon) steroid hormone. It is a naturally-occurring corticosteroid metabolite that is also used as a pharmaceutical prodrug...
    16 KB (1,509 words) - 14:16, 24 December 2023
  • Thumbnail for Corticosteroid
    the mitochondria and require adrenodoxin as a cofactor (except 21-hydroxylase and 17α-hydroxylase). Aldosterone and corticosterone share the first part...
    41 KB (4,133 words) - 00:10, 23 March 2024
  • Thumbnail for Androstenedione
    biosynthesized in one of two ways. The primary pathway involves conversion of 17α-hydroxypregnenolone to DHEA by way of 17,20-lyase, with subsequent conversion...
    19 KB (1,899 words) - 15:35, 24 January 2024
  • Thumbnail for 17α-Estradiol
    17α-Estradiol (also known as 17α-E2, 17-epiestradiol, alfatradiol, or estra-1,3,5(10)-triene-3,17α-diol) is a minor and weak endogenous steroidal estrogen...
    10 KB (925 words) - 09:01, 24 January 2024
  • Thumbnail for Dihydrotestosterone
    bond of testosterone. DHT may also be synthesized from progesterone and 17α-hydroxyprogesterone via the androgen backdoor pathway in the absence of testosterone...
    67 KB (6,821 words) - 14:50, 18 March 2024
  • Thumbnail for Corticosterone
    adrenal glands. In the very rare case of congenital adrenal hyperplasia due to 17α-hydroxylase deficiency cortisol production is blocked. In many species, including...
    12 KB (1,193 words) - 15:46, 10 December 2023
  • Thumbnail for Testosterone
    In the next step, two additional carbon atoms are removed by the CYP17A1 (17α-hydroxylase/17,20-lyase) enzyme in the endoplasmic reticulum to yield a variety...
    149 KB (15,647 words) - 18:10, 15 April 2024
  • Thumbnail for Androstenone
    Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone 21-Hydroxypregnenolone 17α,21-Dihydroxypregnenolone 11β,17α,21-Trihydroxypregnenolone Corticosteroids...
    12 KB (1,148 words) - 01:06, 4 April 2024
  • Thumbnail for Progesterone
    hydroxylated via 17α-hydroxylase (CYP17A1) and 21-hydroxylase (CYP21A2) into 17α-hydroxyprogesterone and 11-deoxycorticosterone (21-hydroxyprogesterone)...
    123 KB (11,590 words) - 02:03, 21 April 2024
  • Thumbnail for Glucocorticoid
    emotional arousal and lasting declarative memory". Trends in Neurosciences. 21 (7): 294–299. doi:10.1016/s0166-2236(97)01214-9. PMID 9683321. S2CID 29839557...
    52 KB (5,448 words) - 13:09, 27 March 2024
  • Thumbnail for 21-Deoxycortisone
    21-Deoxycortisone, also known as 21-desoxycortisone, 11-keto-17α-hydroxyprogesterone, or 17α-hydroxypregn-4-ene-3,11,20-trione, is a naturally occurring...
    3 KB (172 words) - 16:26, 26 April 2023
  • Thumbnail for Epitestosterone
    Epitestosterone, or isotestosterone, also known as 17α-testosterone or as androst-4-en-17α-ol-3-one, is an endogenous steroid and an epimer of the androgen...
    11 KB (1,093 words) - 17:47, 23 April 2024
  • Thumbnail for 5α-Pregnan-17α-ol-3,20-dione
    5α-Pregnan-17α-ol-3,20-dione, also known as 17α-hydroxy-dihydroprogesterone (17‐OH-DHP) is an endogenous steroid, a metabolite of 17α-hydroxyprogesterone...
    11 KB (1,041 words) - 22:30, 10 April 2024
  • Thumbnail for Androstenol
    steroids acting as pheromones in humans?". Physiology & Behavior. 83 (1): 21–9. doi:10.1016/S0031-9384(04)00345-2. PMID 15501487. Johannes J, Weusten AM...
    8 KB (693 words) - 12:26, 20 March 2024