2-Hydroxysaclofen is a GABAB receptor antagonist and an analogue of saclofen. 2-Hydroxysaclofen binds to the GABAB receptor, but this is selective for...

upright to a maximum height of 100 cm (39 in). The heart-shaped leaves are 2–8 centimetres (0.79–3.15 in) long, and have a rough, veined surface. They...

sodium is defined as 0.600 micrograms. Therefore, 2 million units (2 megaunits) of penicillin G is 1.2 g. One unit of penicillin V potassium is defined...

including C-2, C-3, and C-4. C-4 consists of RDX (91%); a plasticizer, dioctyl sebacate (5.3%); and a binder, which is usually polyisobutylene (2.1%); and...

histone deacetylase inhibitor and full agonist of free fatty acid receptor 2, free fatty acid receptor 3, and niacin receptor 1 Derivatives: butyrate (butanoate)...

with unarousable sleep, which can lead to death. Recreational doses of 1–2 g generally provide a feeling of euphoria, and larger doses create deleterious...

Dihydroergolines (e.g., ergoloid (dihydroergotoxine)) Etazepine Etifoxine 2-Substituted phenols (e.g., thymol, eugenol) Imidazoles (e.g., etomidate) Kavalactones...

increase in tendon problems. The risk increased to 3.2 in those over 60 years of age and to 6.2 in those over the age of 60 who were also taking corticosteroids...

industrially using mutants of Brevibacterium flavum, which gives ca. 40 g/L in 2 days using glucose as a carbon source. Glutamine synthesis from glutamate...

which brainwave patterns generally show a desynchronization. In higher doses (2 mg/kg via IV), the EEG will show characteristic spikes. Muscimol primarily...

Disorder: Current and Emerging Therapies". Harvard Review of Psychiatry. 23 (2): 122–133. doi:10.1097/HRP.0000000000000079. PMC 4790835. PMID 25747925. v...

CNQX, an antagonist of both the AMPA and kainate receptors, and 2-hydroxysaclofen, a GABAB receptor antagonist, do not affect quisqualamine's actions...

Experimental and pharmacokinetic studies]". Neuro-Chirurgie (in French). 49 (2-3 Pt 2): 271–5. PMID 12746702. Enserink M (May 2011). "Addiction research. Anonymous...

from Molecular Studies". Plant Signal Behav. 2 (5): 408–9. Bibcode:2007PlSiB...2..408R. doi:10.4161/psb.2.5.4335. PMC 2634229. PMID 19704616. Wikimedia...

BHFF BSPP CGP-7930 CGP-13501 GS-39783 rac-BHFF KK-92A Antagonists: 2-Hydroxysaclofen CGP-35348 CGP-46381 CGP-52432 CGP-54626 CGP-55845 CGP-64213 DAVA Homotaurine...

oxybate dose regimen for the treatment of alcohol dependence (i.e., around 3.2 g/day) is lower than the one for the treatment of narcolepsy (4.5–9 g/night)...

historical perspective on GABAergic drugs". Future Medicinal Chemistry. 3 (2): 163–175. doi:10.4155/fmc.10.285. ISSN 1756-8919. PMID 21428811. v t e...

molecular characteristics, kinetics and mechanism". Biochem. Soc. Trans. 21 (2): 522–7. doi:10.1042/bst0210522. PMID 8359524. Galligan JJ, Wepy JA, Streeter...

at six to ten minutes. The recommended dose for adults is 200 μg every 1–2 minutes until the effect is seen, up to a maximum of 3 mg per hour. It is...

as an intermediate in the production of other chemicals, such as N-methyl-2-pyrrolidone. In humans, GBL acts as a prodrug for gamma-hydroxybutyric acid...

fipronil for desert locust control in Mauritania, and very low doses (0.6-2.0 g a.i./ha) used against grasshoppers in Niger caused impacts on nontarget...

and dicyclohexylamine. 1,3-Butanediol 1,4-Butanediol diglycidyl ether 2-Methyl-2-propyl-1,3-propanediol 4-Amino-1-butanol Weast, Robert C., ed. (1981)...

54 (2): 66–9. PMID 1884802. Dorofeev BF, Kholodov LE (March 1991). "[Pikamilon pharmacokinetics in animals]". Farmakologiia I Toksikologiia. 54 (2): 66–69...

agents at serotonin (5-HT(2) and 5-HT(1A)), dopamine (D(2)) and benzodiazepine receptors". Drug and Alcohol Dependence. 60 (2): 121–132. doi:10...

achieved 3 hours after administration and exceed those in plasma by a factor of 2. Similarly, lung tissue concentrations range from two-fold to five-fold higher...

individuals with severe kidney failure Renal clearance (mL/min/kg) 2.0 Elimination half-life (hrs) 2 Prolonged in congestive heart failure (mean 3.4 hrs) Prolonged...

these individuals, the onset of action of phenibut has been reported to be 2 to 4 hours orally and 20 to 30 minutes rectally, the peak effects are described...

Tetramethylenedisulfotetramine". Journal of Pharmacology and Experimental Therapeutics. 341 (2): 435–446. doi:10.1124/jpet.111.190579. PMC 3336809. PMID 22328574. CDC (2003)...

hydrazine: OC(NH2)2 + N2H4 → OC(NH2)(N2H3) + NH3 A further reaction can occur to give carbohydrazide: OC(NH2)(N2H3) + N2H4 → OC(N2H3)2 + NH3 Semicarbazide...

grand wormwood (Artemisia absinthium), usually as a mix of isomers in a 1:2 ratio. It is also found in various species of Mentha (mint). The biosynthesis...